MYC regulates the antitumor immune response through CD47 and PD-L1
Casey, Stephanie C., Tong, Ling, Li, Yulin, Do, Rachel, Walz, Susanne, Fitzgerald, Kelly N., Gouw, Arvin M., Baylot, Virginie, Gütgemann, Ines, Eilers, Martin, Felsher, Dean W.
Published in Science (American Association for the Advancement of Science) (08.04.2016)
Published in Science (American Association for the Advancement of Science) (08.04.2016)
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Journal Article
The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma
Miess, Heike, Dankworth, Beatrice, Gouw, Arvin M, Rosenfeldt, Mathias, Schmitz, Werner, Jiang, Ming, Saunders, Becky, Howell, Michael, Downward, Julian, Felsher, Dean W, Peck, Barrie, Schulze, Almut
Published in Oncogene (01.10.2018)
Published in Oncogene (01.10.2018)
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Journal Article
MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells
Altman, Brian J., Hsieh, Annie L., Sengupta, Arjun, Krishnanaiah, Saikumari Y., Stine, Zachary E., Walton, Zandra E., Gouw, Arvin M., Venkataraman, Anand, Li, Bo, Goraksha-Hicks, Pankuri, Diskin, Sharon J., Bellovin, David I., Simon, M. Celeste, Rathmell, Jeffrey C., Lazar, Mitchell A., Maris, John M., Felsher, Dean W., Hogenesch, John B., Weljie, Aalim M., Dang, Chi V.
Published in Cell metabolism (01.12.2015)
Published in Cell metabolism (01.12.2015)
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Journal Article
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
Le, Anne, Cooper, Charles R, Gouw, Arvin M, Dinavahi, Ramani, Maitra, Anirban, Deck, Lorraine M, Royer, Robert E, Vander Jagt, David L, Semenza, Gregg L, Dang, Chi V
Published in Proceedings of the National Academy of Sciences - PNAS (02.02.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (02.02.2010)
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Journal Article
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
Xiang, Yan, Stine, Zachary E, Xia, Jinsong, Lu, Yunqi, O'Connor, Roddy S, Altman, Brian J, Hsieh, Annie L, Gouw, Arvin M, Thomas, Ajit G, Gao, Ping, Sun, Linchong, Song, Libing, Yan, Benedict, Slusher, Barbara S, Zhuo, Jingli, Ooi, London L, Lee, Caroline G L, Mancuso, Anthony, McCallion, Andrew S, Le, Anne, Milone, Michael C, Rayport, Stephen, Felsher, Dean W, Dang, Chi V
Published in The Journal of clinical investigation (01.06.2015)
Published in The Journal of clinical investigation (01.06.2015)
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Journal Article
MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism
Shroff, Emelyn H., Eberlin, Livia S., Dang, Vanessa M., Gouw, Arvin M., Gabay, Meital, Adam, Stacey J., Bellovin, David I., Tran, Phuoc T., Philbrick, William M., Garcia-Ocana, Adolfo, Casey, Stephanie C., Li, Yulin, Dang, Chi V., Zare, Richard N., Felsher, Dean W.
Published in Proceedings of the National Academy of Sciences - PNAS (26.05.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (26.05.2015)
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Journal Article
Alteration of the lipid profile in lymphomas induced by MYC overexpression
Eberlin, Livia S., Gabay, Meital, Fan, Alice C., Gouw, Arvin M., Tibshirani, Robert J., Felsher, Dean W., Zare, Richard N.
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.2014)
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Journal Article
Correspondence: Oncogenic MYC persistently upregulates the molecular clock component REV-ERBα
Altman, Brian J, Hsieh, Annie L, Gouw, Arvin M, Dang, Chi V
Published in Nature communications (23.03.2017)
Published in Nature communications (23.03.2017)
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Journal Article
Future space missions and human enhancement: Medical and ethical challenges
Szocik, Konrad, Shelhamer, Mark, Braddock, Martin, Cucinotta, Francis A., Impey, Chris, Worden, Pete, Peters, Ted, Ćirković, Milan M., Smith, Kelly C., Tachibana, Koji, Reiss, Michael J., Norman, Ziba, Gouw, Arvin M., Munévar, Gonzalo
Published in Futures : the journal of policy, planning and futures studies (01.10.2021)
Published in Futures : the journal of policy, planning and futures studies (01.10.2021)
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Journal Article
Age-related decline of sleep-dependent consolidation
SPENCER, Rebecca M. C, GOUW, Arvin M, IVRY, Richard B
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01.07.2007)
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01.07.2007)
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Journal Article
Tumorigenicity of hypoxic respiring cancer cells revealed by a hypoxia—cell cycle dual reporter
Le, Anne, Stine, Zachary E., Nguyen, Christopher, Afzal, Junaid, Sun, Peng, Hamaker, Max, Siegel, Nicholas M., Gouw, Arvin M., Kang, Byung-hak, Yu, Shu-Han, Cochran, Rory L., Sailor, Kurt A., Song, Hongjun, Dang, Chi V.
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2014)
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Journal Article
Mitochondrial copper depletion suppresses triple-negative breast cancer in mice
Cui, Liyang, Gouw, Arvin M, LaGory, Edward L, Guo, Shenghao, Attarwala, Nabeel, Tang, Yao, Qi, Ji, Chen, Yun-Sheng, Gao, Zhou, Casey, Kerriann M, Bazhin, Arkadiy A, Chen, Min, Hu, Leeann, Xie, Jinghang, Fang, Mingxi, Zhang, Cissy, Zhu, Qihua, Wang, Zhiyuan, Giaccia, Amato J, Gambhir, Sanjiv Sam, Zhu, Weiping, Felsher, Dean W, Pegram, Mark D, Goun, Elena A, Le, Anne, Rao, Jianghong
Published in Nature biotechnology (01.03.2021)
Published in Nature biotechnology (01.03.2021)
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Journal Article
Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma
Gouw, Arvin M., Eberlin, Livia S., Margulis, Katherine, Sullivan, Delaney K., Toal, Georgia G., Tong, Ling, Zare, Richard N., Felsher, Dean W.
Published in Proceedings of the National Academy of Sciences - PNAS (25.04.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (25.04.2017)
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Journal Article
The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth
Gouw, Arvin M., Margulis, Katherine, Liu, Natalie S., Raman, Sudha J., Mancuso, Anthony, Toal, Georgia G., Tong, Ling, Mosley, Adriane, Hsieh, Annie L., Sullivan, Delaney K., Stine, Zachary E., Altman, Brian J., Schulze, Almut, Dang, Chi V., Zare, Richard N., Felsher, Dean W.
Published in Cell metabolism (03.09.2019)
Published in Cell metabolism (03.09.2019)
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Journal Article
Cancer Stem Cell Metabolism
Alvina, Fidelia B, Gouw, Arvin M, Le, Anne
Published in Advances in experimental medicine and biology (2021)
Published in Advances in experimental medicine and biology (2021)
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Journal Article
MYC Regulates the HIF2α Stemness Pathway via Nanog and Sox2 to Maintain Self-Renewal in Cancer Stem Cells versus Non-Stem Cancer Cells
Das, Bikul, Pal, Bidisha, Bhuyan, Rashmi, Li, Hong, Sarma, Anupam, Gayan, Sukanya, Talukdar, Joyeeta, Sandhya, Sorra, Bhuyan, Seema, Gogoi, Gayatri, Gouw, Arvin M, Baishya, Debabrat, Gotlib, Jason R, Kataki, Amal C, Felsher, Dean W
Published in Cancer research (Chicago, Ill.) (15.08.2019)
Published in Cancer research (Chicago, Ill.) (15.08.2019)
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Journal Article
THE CRISPR APPLE ON THE TREE OF KNOWLEDGE CONFERENCE HIGHLIGHTS: CRISPR IN SCIENCE, ETHICS, AND RELIGION: with Arvin M. Gouw, “The CRISPR Apple on the Tree of Knowledge Conference Highlights: CRISPR in Science, Ethics, and Religion”; Arvin M. Gouw, “Introducing the Brave New CRISPR World”; Roger R. Adams, “Moral Decisions about Human Germ‐line Modification”; Constance M. Bertka, “Navigating the Future in a Sea of CRISPR Uncertainty”; and Linda Groff, “CRISPR, CRISPR on My Mind.”
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Journal Article