Effect of the mGlu2 positive allosteric modulator biphenyl-indanone A as a monotherapy and as adjunct to a low dose of L-DOPA in the MPTP-lesioned marmoset
Kang, Woojin, Frouni, Imane, Kwan, Cynthia, Bédard, Dominique, Nuara, Stephen G, Hamadjida, Adjia, Gourdon, Jim C, Huot, Philippe
Published in The European journal of neuroscience (27.06.2024)
Published in The European journal of neuroscience (27.06.2024)
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The 5‐HT2A/2C inverse agonist nelotanserin alleviates L‐DOPA‐induced dyskinesia in the MPTP‐lesioned marmoset
Kwan, Cynthia, Frouni, Imane, Bédard, Dominique, Hamadjida, Adjia, Nuara, Stephen G., Gourdon, Jim C., Huot, Philippe
Published in The European journal of neuroscience (01.03.2024)
Published in The European journal of neuroscience (01.03.2024)
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Journal Article
The 5-HT 2A/2C inverse agonist nelotanserin alleviates L-DOPA-induced dyskinesia in the MPTP-lesioned marmoset
Kwan, Cynthia, Frouni, Imane, Bédard, Dominique, Hamadjida, Adjia, Nuara, Stephen G, Gourdon, Jim C, Huot, Philippe
Published in The European journal of neuroscience (01.03.2024)
Published in The European journal of neuroscience (01.03.2024)
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Effect of the mGlu4 positive allosteric modulator ADX-88178 on parkinsonism, psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset
Frouni, Imane, Kwan, Cynthia, Bédard, Dominique, Kang, Woojin, Hamadjida, Adjia, Nuara, Stephen G., Gourdon, Jim C., Huot, Philippe
Published in Psychopharmacology (01.10.2023)
Published in Psychopharmacology (01.10.2023)
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Anti-parkinsonian effect of the mGlu2 positive allosteric modulator LY-487,379 as monotherapy and adjunct to a low L-DOPA dose in the MPTP-lesioned marmoset
Frouni, Imane, Kwan, Cynthia, Belliveau, Sébastien, Hamadjida, Adjia, Bédard, Dominique, Nuara, Stephen G., Gourdon, Jim C., Huot, Philippe
Published in European journal of pharmacology (15.01.2023)
Published in European journal of pharmacology (15.01.2023)
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Journal Article
Effect of the glycine transporter 1 inhibitor ALX-5407 on dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset
Frouni, Imane, Belliveau, Sébastien, Maddaford, Shawn, Nuara, Stephen G., Gourdon, Jim C., Huot, Philippe
Published in European journal of pharmacology (05.11.2021)
Published in European journal of pharmacology (05.11.2021)
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The highly selective 5-HT2A antagonist EMD-281,014 reduces dyskinesia and psychosis in the l-DOPA-treated parkinsonian marmoset
Hamadjida, Adjia, Nuara, Stephen G., Bédard, Dominique, Gaudette, Fleur, Beaudry, Francis, Gourdon, Jim C., Huot, Philippe
Published in Neuropharmacology (01.09.2018)
Published in Neuropharmacology (01.09.2018)
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Journal Article
Positive allosteric mGluR2 modulation with BINA alleviates dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset
Kang, Woojin, Frouni, Imane, Bédard, Dominique, Kwan, Cynthia, Hamadjida, Adjia, Nuara, Stephen G, Gourdon, Jim C, Huot, Philippe
Published in Naunyn-Schmiedeberg's archives of pharmacology (11.06.2024)
Published in Naunyn-Schmiedeberg's archives of pharmacology (11.06.2024)
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5-HT2A blockade for dyskinesia and psychosis in Parkinson’s disease: is there a limit to the efficacy of this approach? A study in the MPTP-lesioned marmoset and a literature mini-review
Kwan, Cynthia, Frouni, Imane, Bédard, Dominique, Nuara, Stephen G., Gourdon, Jim C., Hamadjida, Adjia, Huot, Philippe
Published in Experimental brain research (01.02.2019)
Published in Experimental brain research (01.02.2019)
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Journal Article
Selective blockade of the 5-HT3 receptor acutely alleviates dyskinesia and psychosis in the parkinsonian marmoset
Kwan, Cynthia, Nuara, Stephen G., Bédard, Dominique, Gaudette, Fleur, Gourdon, Jim C., Beaudry, Francis, Huot, Philippe
Published in Neuropharmacology (01.01.2021)
Published in Neuropharmacology (01.01.2021)
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Journal Article
The mGlu2/3 antagonist LY-341,495 reverses the anti-dyskinetic and anti-psychotic effects of the mGlu2 activators LY-487,379 and LY-354,740 in the MPTP-lesioned marmoset
Nuara, Stephen G., Hamadjida, Adjia, Gourdon, Jim C., Huot, Philippe
Published in Journal of Neural Transmission (01.07.2020)
Published in Journal of Neural Transmission (01.07.2020)
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Selective metabotropic glutamate receptor 2 positive allosteric modulation alleviates L-DOPA-induced psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset
Sid-Otmane, Lamia, Hamadjida, Adjia, Nuara, Stephen G., Bédard, Dominique, Gaudette, Fleur, Gourdon, Jim C., Michaud, Véronique, Beaudry, Francis, Panisset, Michel, Huot, Philippe
Published in European journal of pharmacology (15.04.2020)
Published in European journal of pharmacology (15.04.2020)
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Additive effects of mGluR2 positive allosteric modulation, mGluR2 orthosteric stimulation and 5-HT2AR antagonism on dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset
Nuara, Stephen G, Gourdon, Jim C, Maddaford, Shawn, Huot, Philippe
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.12.2021)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.12.2021)
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Journal Article
The highly selective 5-HT 2A antagonist EMD-281,014 reduces dyskinesia and psychosis in the l-DOPA-treated parkinsonian marmoset
Hamadjida, Adjia, Nuara, Stephen G, Bédard, Dominique, Gaudette, Fleur, Beaudry, Francis, Gourdon, Jim C, Huot, Philippe
Published in Neuropharmacology (01.09.2018)
Published in Neuropharmacology (01.09.2018)
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Journal Article
The mGluR2/3 orthosteric agonist LY-404,039 reduces dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset
Kang, Woojin, Nuara, Stephen G., Bédard, Dominique, Frouni, Imane, Kwan, Cynthia, Hamadjida, Adjia, Gourdon, Jim C., Gaudette, Fleur, Beaudry, Francis, Huot, Philippe
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.10.2023)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.10.2023)
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