Pharmacological characterization of GLPG1972/S201086, a potent and selective small-molecule inhibitor of ADAMTS5
Clement-Lacroix, P., Little, C.B., Smith, M.M., Cottereaux, C., Merciris, D., Meurisse, S., Mollat, P., Touitou, R., Brebion, F., Gosmini, R., De Ceuninck, F., Botez, I., Lepescheux, L., van der Aar, E., Christophe, T., Vandervoort, N., Blanqué, R., Comas, D., Deprez, P., Amantini, D.
Published in Osteoarthritis and cartilage (01.02.2022)
Published in Osteoarthritis and cartilage (01.02.2022)
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Journal Article
OP0258 Efficacy of the highly selective adamts-5 inhibitor glpg1972 in the rat meniscectomy model
Lepescheux, L., Clement-Lacroix, P., Merciris, D., Meurisse, S., Borgonovi, M., Cottereaux, C., Mollat, P., Brebion, F., Gosmini, R., De Ceuninck, F., Botez, I., van der Aar, E., Christophe, T., Vandervoort, N., Blanqué, R., Comas, D., Deprez, P., Amantini, D.
Published in Annals of the rheumatic diseases (01.06.2018)
Published in Annals of the rheumatic diseases (01.06.2018)
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Journal Article
GLPG1972: a potent, selective, orally available adamts-5 inhibitor for the treatment of OA
Clement-Lacroix, P, Little, C, Meurisse, S, Blanqué, R, Mollat, P, Brebion, F, Gosmini, R, De Ceuninck, F, Botez, I, Lepescheux, L, van der Aar, E, Christophe, T, Vandervoort, N, Cottereaux, C, Comas, D, Deprez, P, Amantini, D
Published in Osteoarthritis and cartilage (01.04.2017)
Published in Osteoarthritis and cartilage (01.04.2017)
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Journal Article
ADAMTS-5 inhibition with the potent and highly selective inhibitor GLPG1972 results in strong disease-modifying OA drug effects in the rat meniscectomy model
Clement-Lacroix, P., Meurisse, S., Lepescheux, L., Merciris, D., Borgonovi, M., Cottereaux, C., Mollat, P., Brebion, F., Gosmini, R., De Ceuninck, F., Botez, I., Christophe, T., van der Aar, E.E., Vandervoort, N., Blanqué, R., Comas, D., Deprez, P., Amantini, D.
Published in Osteoarthritis and cartilage (01.04.2018)
Published in Osteoarthritis and cartilage (01.04.2018)
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Journal Article
OP0180 Pharmacological characterization of the ADAMTS-5 inhibitor GLPG1972: an oral anti-catabolic agent for the treatment of osteoarthritis
Clement-Lacroix, P, Little, C, Blanqué, R, Meurisse, S, Mollat, P, Brebion, F, Gosmini, R, Ceuninck, F De, Botez, I, Lepescheux, L, Aar, E van der, Christophe, T, Vandervoort, N, Cottereaux, C, Comas, D, Deprez, P, Amantini, D
Published in Annals of the rheumatic diseases (01.06.2017)
Published in Annals of the rheumatic diseases (01.06.2017)
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Journal Article
α-t-butyl- and α-i-propyl-ortho-hydroxybenzylamines: Racemic synthesis/resolution and asymmetric synthesis
Bernardinelli, Gérald, Fernandez, Daniel, Gosmini, Romain, Meier, Peter, Ripa, Alberto, Schüpfer, Patrick, Treptow, Björn, Kündig, E. Peter
Published in Chirality (New York, N.Y.) (2000)
Published in Chirality (New York, N.Y.) (2000)
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Journal Article
Regio and enantioselective synthesis of 4-carbomethoxymethyl-1,4 dihydropyridines
Raussou, Sabine, Gosmini, Romain, Mangeney, Pierre, Alexakis, Alexandre, Commerçon, Monique
Published in Tetrahedron letters (25.07.1994)
Published in Tetrahedron letters (25.07.1994)
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Journal Article
Diastereoselective addition of organocuprates on 1,4-dihydropyridine-3-carboxaldehydes. Synthesis of chiral 1,4-dihydropyridyl-3-alcohols and pyridyl-3-alcohols
Mangeney, Pierre, Gosmini, Romain, Raussou, Sabine, Commerçon, Monique
Published in Tetrahedron letters (01.10.1993)
Published in Tetrahedron letters (01.10.1993)
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