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GCN2 INHIBITORS AND USES THEREOF

GCN2 INHIBITORS AND USES THEREOF

by XIAO, Yufang, ENO, Meredith Suzanne, FRAYSSE, Damien, NORTH, Kiri, BLEICH, Matthew, QIU, Hui, MOCHALKIN, Igor, DONG, Huijun, CHARRIER, Jean-Damien, STORCK, Pierre-Henri, DURRANT, Steven, EVERITT, Simon, KNEGTEL, Ronald, PULLIN, Robert, TWIN, Heather Clare, ETXEBARRIA I JARDI, Gorka, PORICHIS, Filippos
Year of Publication 01.09.2021

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2-amino-6-fluoro-N-[5-fluoro-pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as ATR kinase inhibitor, its preparation, different solid forms and radiolabelled derivatives thereof

2-amino-6-fluoro-N-[5-fluoro-pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as ATR kinase inhibitor, its preparation, different solid forms and radiolabelled derivatives thereof

by PIERARD, Francoise, ZWICKER, Carl, SHAW, David Matthew, ZHANG, Yuegang, MEDEK, Ales, FRAYSSE, Damien, DAVIS, Christopher John, PEGG, Simon, CHARRIER, Jean-Damien, ALEM, Naziha, SANGHVI, Tapan, WALDO, Michael, PINDER, Joanne, STUDLEY, John, PANESAR, Maninder, ETXEBARRIA I JARDI, Gorka
Year of Publication 26.08.2021

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Compounds useful as inhibitors of ATR kinase

Compounds useful as inhibitors of ATR kinase

by Davis, Chris, Twin, Heather, Charrier, Jean-Damien, Kay, David, Knegtel, Ronald, Fraysse, Damien, Jimenez, Juan-Miguel, Shaw, David, Panesar, Maninder, O'Donnell, Michael, Studley, John, Storck, Pierre-Henri, Davis, Rebecca, Etxebarria I Jardi, Gorka, Middleton, Donald, Boyall, Dean, Pierard, Francoise, Ahmad, Nadia, Pinder, Joanne, Durrant, Steven
Year of Publication 28.06.2022

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RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-(5-FLUORO-PYRIDIN-3-YL)- PYRAZOLO(1,5-A)PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-(5-FLUORO-PYRIDIN-3-YL)- PYRAZOLO(1,5-A)PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

by DAVIS Chris, KNEGTEL Ronald, FRAYSSE Damien, ETXEBARRIA I JARDI Gorka, PANESAR Maninder, PIERARD Francoise, AHMAD Nadia, CHARRIER Jean-Damien, PINDER Joanne, STUDLEY John, STORCK Pierre-Henri
Year of Publication 30.06.2020

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RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

by AHMAD, NADIA, KNEGTEL, RONALD, STORCK, PIERRE-HENRI, FRAYSSE, DAMIEN, STUDLEY, JOHN, CHARRIER, JEAN-DAMIEN, ETXEBARRIA I JARDI, GORKA, DAVIS, CHRIS, PINDER, JOANNE, PANESAR, MANINDER, PIERARD, FRANCOISE
Year of Publication 15.06.2020

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RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

by Panesar, Maninder, Davis, Chris, Studley, John, Charrier, Jean-Damien, Storck, Pierre-Henri, Etxebarria I Jardi, Gorka, Knegtel, Ronald, Fraysse, Damien, Pierard, Francoise, Ahmad, Nadia, Pinder, Joanne
Year of Publication 29.05.2020

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RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

by JOANNE PINDER, RONALD KNEGTEL, PIERRE-HENRI STORCK, DAMIEN FRAYSSE, MANINDER PANESAR, JOHN STUDLEY, FRANCOISE PIERARD, JEAN-DAMIEN CHARRIER, CHRIS DAVIS, NADIA AHMAD, GORKA ETXEBARRIA I JARDI
Year of Publication 27.05.2020

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RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

by AHMAD, Nadia, PIERARD, Francoise, PINDER, Joanne, STUDLEY, John, FRAYSSE, Damien, PANESAR, Maninder, KNEGTEL, Ronald, ETXEBARRIA I JARDI, Gorka, CHARRIER, Jean-Damien, DAVIS, Chris, STORCK, Pierre-Henri
Year of Publication 27.05.2020

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Patent

RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

by AHMAD, Nadia, PIERARD, Francoise, PINDER, Joanne, STUDLEY, John, FRAYSSE, Damien, PANESAR, Maninder, KNEGTEL, Ronald, ETXEBARRIA I JARDI, Gorka, CHARRIER, Jean-Damien, DAVIS, Chris, STORCK, Pierre-Henri
Year of Publication 11.05.2020

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RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

by AHMAD, NADIA, KNEGTEL, RONALD, STORCK, PIERRE-HENRI, FRAYSSE, DAMIEN, STUDLEY, JOHN, CHARRIER, JEAN-DAMIEN, ETXEBARRIA I JARDI, GORKA, DAVIS, CHRIS, PINDER, JOANNE, PANESAR, MANINDER, PIERARD, FRANCOISE
Year of Publication 30.04.2020

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Patent

GCN2 INHIBITORS AND USES THEREOF

GCN2 INHIBITORS AND USES THEREOF

by Bleich, Matthew, Charrier, Jean-Damien, Knegtel, Ronald, Eno, Meredith Suzanne, Fraysse, Damien, Everitt, Simon, Qiu, Hui, Xiao, Yufang, Mochalkin, Igor, Pullin, Robert, Storck, Pierre-Henri, Etxebarria I Jardi, Gorka, Twin, Heather Clare, North, Kiri, Durrant, Steven, Dong, Huijun, Porichis, Filippos
Year of Publication 11.02.2021

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COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

by PIERARD, Francoise, ZWICKER, Carl, SHAW, David Matthew, ZHANG, Yuegang, MEDEK, Ales, FRAYSSE, Damien, DAVIS, Christopher John, PEGG, Simon, CHARRIER, Jean-Damien, ALEM, Naziha, SANGHVI, Tapan, WALDO, Michael, PINDER, Joanne, STUDLEY, John, PANESAR, Maninder, ETXEBARRIA I JARDI, Gorka
Year of Publication 04.02.2021

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2-AMINO-N-(PIPERIDIN-1-YL-PYRIDIN-3-YL) PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMID AS INHIBITOR OF ATR KINASE

2-AMINO-N-(PIPERIDIN-1-YL-PYRIDIN-3-YL) PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMID AS INHIBITOR OF ATR KINASE

by PIERARD, Francoise, KAY, David, FRAYSSE, Damien, JIMENEZ, Juan-Miguel, ODONNELL, Michael, TWIN, Heather, CHARRIER, Jean-Damien, MIDDELTON, Donald, STORCK, Pierre-Henri, AHMAD, Nadia, DURRANT, Steven, PINDER, Joanne, STUDLEY, John, BOYALL, Dean, PANESAR, Maninder, SHAW, David, KNEGTEL, Ronald, ETXEBARRIA I JARDI, Gorka, DAVIS, Chris, DAVIS, Rebecca
Year of Publication 28.12.2021

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2-AMINO-N-(PIPERIDIN-1-YL-PYRIDIN-3-YL) PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMID AS INHIBITOR OF ATR KINASE

2-AMINO-N-(PIPERIDIN-1-YL-PYRIDIN-3-YL) PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMID AS INHIBITOR OF ATR KINASE

by Odonnell, Michael, Middelton, Donald, Davis, Chris, Twin, Heather, Charrier, Jean-Damien, Kay, David, Knegtel, Ronald, Fraysse, Damien, Jimenez, Juan-Miguel, Shaw, David, Panesar, Maninder, Studley, John, Storck, Pierre-Henri, Davis, Rebecca, Etxebarria I Jardi, Gorka, Boyall, Dean, Pierard, Francoise, Ahmad, Nadia, Pinder, Joanne, Durrant, Steven
Year of Publication 10.12.2021

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GCN2 INHIBITORS AND USES THEREOF

GCN2 INHIBITORS AND USES THEREOF

by XIAO, Yufang, ENO, Meredith Suzanne, FRAYSSE, Damien, NORTH, Kiri, BLEICH, Matthew, QIU, Hui, MOCHALKIN, Igor, DONG, Huijun, CHARRIER, Jean-Damien, STORCK, Pierre-Henri, DURRANT, Steven, EVERITT, Simon, KNEGTEL, Ronald, PULLIN, Robert, TWIN, Heather Clare, ETXEBARRIA I JARDI, Gorka, PORICHIS, Filippos
Year of Publication 09.12.2020

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Patent

RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

by AHMAD, Nadia, PIERARD, Francoise, PINDER, Joanne, STUDLEY, John, FRAYSSE, Damien, PANESAR, Maninder, KNEGTEL, Ronald, ETXEBARRIA I JARDI, Gorka, CHARRIER, Jean-Damien, DAVIS, Chris, STORCK, Pierre-Henri
Year of Publication 11.12.2019

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2-AMINO-N-(PIPERIDIN-1-YL-PYRIDIN-3-YL) PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMID AS INHIBITOR OF ATR KINASE

2-AMINO-N-(PIPERIDIN-1-YL-PYRIDIN-3-YL) PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMID AS INHIBITOR OF ATR KINASE

by AHMAD, NADIA, DAVIS, REBECCA, DURRANT, STEVEN, STUDLEY, JOHN, CHARRIER, JEAN-DAMIEN, ETXEBARRIA I JARDI, GORKA, KAY, DAVID, MIDDELTON, DONALD, DAVIS, CHRIS, PINDER, JOANNE, SHAW, DAVID, JIMENEZ, JUAN-MIGUEL, PANESAR, MANINDER, PIERARD, FRANCOISE, ODONNELL, MICHAEL, KNEGTEL, RONALD, TWIN, HEATHER, STORCK, PIERRE-HENRI, FRAYSSE, DAMIEN, BOYALL, DEAN
Year of Publication 08.11.2021

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COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

by AHMAD, NADIA, DAVIS, REBECCA, DURRANT, STEVEN, STUDLEY, JOHN, CHARRIER, JEAN-DAMIEN, ETXEBARRIA I JARDI, GORKA, KAY, DAVID, DAVIS, CHRIS, PINDER, JOANNE, SHAW, DAVID, JIMENEZ, JUAN-MIGUEL, PANESAR, MANINDER, PIERARD, FRANCOISE, MIDDLETON, DONALD, ODONNELL, MICHAEL, KNEGTEL, RONALD, TWIN, HEATHER, STORCK, PIERRE-HENRI, FRAYSSE, DAMIEN, BOYALL, DEAN
Year of Publication 19.10.2021

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2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as atr kinase inhibitor, its preparation, different solid forms and radiolabelled derivatives thereof

2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as atr kinase inhibitor, its preparation, different solid forms and radiolabelled derivatives thereof

by Sanghvi, Tapan, Zwicker, Carl, Alem, Naziha, Charrier, Jean-Damien, Fraysse, Damien, Shaw, David, Zhang, Yuegang, Waldo, Michael, Panesar, Maninder, Pegg, Simon, Studley, John, Etxebarria I Jardi, Gorka, Pierard, Francoise, Pinder, Joanne, Medek, Ales, Davis, Christopher
Year of Publication 30.10.2020

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Patent

Compounds useful as inhibitors of ATR kinase

Compounds useful as inhibitors of ATR kinase

by Sanghvi, Tapan, Zwicker, Carl, Alem, Naziha, Charrier, Jean-Damien, Fraysse, Damien, Zhang, Yuegang, Shaw, David Matthew, Pegg, Simon, Waldo, Michael, Panesar, Maninder, Studley, John, Davis, Christopher John, Etxebarria I Jardi, Gorka, Pierard, Francoise, Pinder, Joanne, Medek, Ales
Year of Publication 27.10.2020

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