Bacterial killing by complement requires membrane attack complex formation via surface‐bound C5 convertases
Heesterbeek, Dani AC, Bardoel, Bart W, Parsons, Edward S, Bennett, Isabel, Ruyken, Maartje, Doorduijn, Dennis J, Gorham, Ronald D, Berends, Evelien TM, Pyne, Alice LB, Hoogenboom, Bart W, Rooijakkers, Suzan HM
Published in The EMBO journal (15.02.2019)
Published in The EMBO journal (15.02.2019)
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Journal Article
Quantitative Modeling of the Alternative Pathway of the Complement System
Zewde, Nehemiah, Gorham, Jr, Ronald D, Dorado, Angel, Morikis, Dimitrios
Published in PloS one (31.03.2016)
Published in PloS one (31.03.2016)
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Journal Article
Purified complement C3b triggers phagocytosis and activation of human neutrophils via complement receptor 1
Boero, Elena, Gorham, Jr, Ronald D, Francis, Emmet A, Brand, Jonathan, Teng, Lay Heng, Doorduijn, Dennis J, Ruyken, Maartje, Muts, Remy M, Lehmann, Christian, Verschoor, Admar, van Kessel, Kok P M, Heinrich, Volkmar, Rooijakkers, Suzan H M
Published in Scientific reports (06.01.2023)
Published in Scientific reports (06.01.2023)
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Journal Article
Molecular Analysis of the Interaction between Staphylococcal Virulence Factor Sbi-IV and Complement C3d
Gorham, Ronald D., Rodriguez, Wilson, Morikis, Dimitrios
Published in Biophysical journal (04.03.2014)
Published in Biophysical journal (04.03.2014)
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Journal Article
Functional Characterization of Alternative and Classical Pathway C3/C5 Convertase Activity and Inhibition Using Purified Models
Zwarthoff, Seline A, Berends, Evelien T M, Mol, Sanne, Ruyken, Maartje, Aerts, Piet C, Józsi, Mihály, de Haas, Carla J C, Rooijakkers, Suzan H M, Gorham, Jr, Ronald D
Published in Frontiers in immunology (23.07.2018)
Published in Frontiers in immunology (23.07.2018)
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Journal Article
Viral regulators of complement activation: structure, function and evolution
Ojha, Hina, Panwar, Hemendra Singh, Gorham, Jr, Ronald D, Morikis, Dimitrios, Sahu, Arvind
Published in Molecular immunology (01.10.2014)
Published in Molecular immunology (01.10.2014)
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Journal Article
AESOP: A Python Library for Investigating Electrostatics in Protein Interactions
Harrison, Reed E.S., Mohan, Rohith R., Gorham, Ronald D., Kieslich, Chris A., Morikis, Dimitrios
Published in Biophysical journal (09.05.2017)
Published in Biophysical journal (09.05.2017)
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Journal Article
An evaluation of Poisson-Boltzmann electrostatic free energy calculations through comparison with experimental mutagenesis data
Gorham Jr, Ronald D., Kieslich, Chris A., Nichols, Aaron, Sausman, Noriko U., Foronda, Marisse, Morikis, Dimitrios
Published in Biopolymers (01.11.2011)
Published in Biopolymers (01.11.2011)
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Journal Article
A theoretical view of the C3d:CR2 binding controversy
Mohan, Rohith R., Gorham, Ronald D., Morikis, Dimitrios
Published in Molecular immunology (01.03.2015)
Published in Molecular immunology (01.03.2015)
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Journal Article
Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes
Berends, Evelien T M, Gorham, Jr, Ronald D, Ruyken, Maartje, Soppe, Jasper A, Orhan, Hatice, Aerts, Piet C, de Haas, Carla J C, Gros, Piet, Rooijakkers, Suzan H M
Published in BMC biology (09.11.2015)
Published in BMC biology (09.11.2015)
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Journal Article
Energetic evaluation of binding modes in the C3d and Factor H (CCP 19-20) complex
E S Harrison, Reed, Gorham, Jr, Ronald D, Morikis, Dimitrios
Published in Protein science (01.05.2015)
Published in Protein science (01.05.2015)
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Journal Article
Molecular Dynamics in Drug Design: New Generations of Compstatin Analogs
Tamamis, Phanourios, López de Victoria, Aliana, Gorham Jr, Ronald D., Bellows-Peterson, Meghan L., Pierou, Panayiota, Floudas, Christodoulos A., Morikis, Dimitrios, Archontis, Georgios
Published in Chemical biology & drug design (01.05.2012)
Published in Chemical biology & drug design (01.05.2012)
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Journal Article
Staphylococcal Immune Evasion Proteins: Structure, Function, and Host Adaptation
Koymans, Kirsten J., Vrieling, Manouk, Gorham, Ronald D., van Strijp, Jos A. G.
Published in Current topics in microbiology and immunology (01.01.2017)
Published in Current topics in microbiology and immunology (01.01.2017)
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Book Chapter
Journal Article
Role of Electrostatic Hotspots in the Selectivity of Complement Control Proteins Toward Human and Bovine Complement Inhibition
Narkhede, Yogesh B, Gautam, Avneesh K, Hsu, Rohaine V, Rodriguez, Wilson, Zewde, Nehemiah T, Harrison, Reed E S, Arantes, Pablo R, Gaieb, Zied, Gorham, Jr, Ronald D, Kieslich, Chris, Morikis, Dimitrios, Sahu, Arvind, Palermo, Giulia
Published in Frontiers in molecular biosciences (16.03.2021)
Published in Frontiers in molecular biosciences (16.03.2021)
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Journal Article
Virtual Screening of Chemical Compounds for Discovery of Complement C3 Ligands
Mohan, Rohith R, Wilson, Mark, Gorham, Ronald D, Harrison, Reed E. S, Morikis, Vasilios A, Kieslich, Chris A, Orr, Asuka A, Coley, Alexis V, Tamamis, Phanourios, Morikis, Dimitrios
Published in ACS omega (30.06.2018)
Published in ACS omega (30.06.2018)
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Journal Article
Hybrid flagellin as a T cell independent vaccine scaffold
Bennett, Kaila M, Gorham, Jr, Ronald D, Gusti, Veronica, Trinh, Lien, Morikis, Dimitrios, Lo, David D
Published in BMC biotechnology (12.08.2015)
Published in BMC biotechnology (12.08.2015)
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Journal Article
New Compstatin Peptides Containing N‑Terminal Extensions and Non-Natural Amino Acids Exhibit Potent Complement Inhibition and Improved Solubility Characteristics
Gorham, Ronald D, Forest, David L, Khoury, George A, Smadbeck, James, Beecher, Consuelo N, Healy, Evangeline D, Tamamis, Phanourios, Archontis, Georgios, Larive, Cynthia K, Floudas, Christodoulos A, Radeke, Monte J, Johnson, Lincoln V, Morikis, Dimitrios
Published in Journal of medicinal chemistry (22.01.2015)
Published in Journal of medicinal chemistry (22.01.2015)
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Journal Article