Dynamic Beat-to-Beat Modeling of the QT-RR Interval Relationship: Analysis of QT Prolongation during Alterations of Autonomic State versus Human Ether a-go-go-Related Gene Inhibition
Fossa, Anthony A, Wisialowski, Todd, Magnano, Anthony, Wolfgang, Eric, Winslow, Roxanne, Gorczyca, William, Crimin, Kimberly, Raunig, David L
Published in The Journal of pharmacology and experimental therapeutics (01.01.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2005)
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Pharmacokinetic-pharmacodynamic modelling of the effect of Moxifloxacin on QTc prolongation in telemetered cynomolgus monkeys
Watson, Kenny J, Gorczyca, William P, Umland, John, Zhang, Ying, Chen, Xian, Sun, Sunny Z, Fermini, Bernard, Holbrook, Mark, Van Der Graaf, Piet H
Published in Journal of pharmacological and toxicological methods (01.05.2011)
Published in Journal of pharmacological and toxicological methods (01.05.2011)
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Changes in QRS duration and cardiac conduction time in the anesthetized guinea pig to evaluate functional Nav1.5 channel inhibition
Wolfgang, Eric A., Gorczyca, William P., Wisialowski, Todd A.
Published in Journal of pharmacological and toxicological methods (01.07.2011)
Published in Journal of pharmacological and toxicological methods (01.07.2011)
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Effects of milrinone on myocardial contractility across different species
Ringer, Laura W., Austin-LaFrance, Robert, Gorczyca, William P., Wolfgang, Eric A., Wisialowski, Todd A., Steidl, Jill
Published in Journal of pharmacological and toxicological methods (01.07.2011)
Published in Journal of pharmacological and toxicological methods (01.07.2011)
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Novel Nonnucleoside Inhibitor of Hepatitis C Virus RNA-Dependent RNA Polymerase
HOWE, Anita Y. M, BLOOM, Johnathan, GORCZYCA, William P, HERRRNANN, Steve, JOHANN, Stephen, XIAOQUN JIANG, KIMBERLAND, Michelle L, KRISNAMURTHY, Girija, OLSON, Matthew, ORLOWSKI, Mark, SWANBERG, Steve, THOMPSON, Ian, BALDICK, Carl J, THORN, Megan, DEL VECCHIO, Alfred, YOUNG, Dorothy C, VAN ZEIJL, Marja, ELLINGBOE, John W, UPESLACIS, Janis, COLLETT, Marc, MANSOUR, Tarek S, O'CONNELL, John F, BENETATOS, Christopher A, HUIMING CHENG, CHRISTENSEN, Joel S, CHUNDURU, Srinivas K, COBURN, Glen A, FELD, Boris, GOPALSAMY, Ariamala
Published in Antimicrobial Agents and Chemotherapy (01.12.2004)
Published in Antimicrobial Agents and Chemotherapy (01.12.2004)
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Citrate infusion produces ionic hypocalcemia, hypomagnesemia and associated cardiovascular changes in the sling-restrained beagle dog—A PK/PD analysis
Ringer, Laura, Gorczyca, William, Steidl-Nichols, Jill, Flynn, Declan
Published in Journal of pharmacological and toxicological methods (01.07.2013)
Published in Journal of pharmacological and toxicological methods (01.07.2013)
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Evidence of reverse rate-dependent prolongation of QT/QTc with moxifloxacin in conscious telemetered nonhuman primates
Wisialowski, Todd, Barnes, Robert, Cordes, Jason, Gorczyca, William, Harris, Peter, Steidl-Nichols, Jill
Published in Journal of pharmacological and toxicological methods (01.07.2013)
Published in Journal of pharmacological and toxicological methods (01.07.2013)
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Translation of L-type calcium channel block: From in vitro assays to in vivo models
Sun, Sunny Z., Ramirez, David, Gorczyca, William P., Foote, Stephen C., Hemkens, Michelle D., Bassyouni, Asser, Jenkinson, Stephen, Wisialowski, Todd A.
Published in Journal of pharmacological and toxicological methods (01.07.2013)
Published in Journal of pharmacological and toxicological methods (01.07.2013)
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Cross species PKPD modeling of moxifloxacin effects on cardiac repolarization
Gorczyca, William, Wolfgang, Eric, Watson, Kenny, Wolford, David, Zhang, Ying, Steidl, Jill, Koup, Jeff, Wisialowski, Todd
Published in Journal of pharmacological and toxicological methods (01.07.2011)
Published in Journal of pharmacological and toxicological methods (01.07.2011)
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Electrical alternans and hemodynamics in the anesthetized guinea pig can discriminate the cardiac safety of antidepressants
Fossa, Anthony A., Gorczyca, William, Wisialowski, Todd, Yasgar, Adam, Wang, Ellen, Crimin, Kimberly, Volberg, Walter, Zhou, Jun
Published in Journal of pharmacological and toxicological methods (01.01.2007)
Published in Journal of pharmacological and toxicological methods (01.01.2007)
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Pharmacokinetic-pharmacodynamic modelling of the effect of Moxifloxacin on QT sub(c prolongation in telemetered cynomolgus monkeys)
Watson, Kenny J, Gorczyca, William P, Umland, John, Zhang, Ying, Chen, Xian, Sun, Sunny Z, Fermini, Bernard, Holbrook, Mark, Van der Graaf, Piet H
Published in Journal of pharmacological and toxicological methods (01.06.2011)
Published in Journal of pharmacological and toxicological methods (01.06.2011)
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Pharmacokinetic–pharmacodynamic modelling of the effect of Moxifloxacin on QT c prolongation in telemetered cynomolgus monkeys
Watson, Kenny J., Gorczyca, William P., Umland, John, Zhang, Ying, Chen, Xian, Sun, Sunny Z., Fermini, Bernard, Holbrook, Mark, Van Der Graaf, Piet H.
Published in Journal of pharmacological and toxicological methods (2011)
Published in Journal of pharmacological and toxicological methods (2011)
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Hemodynamic effects of milrinone, CI-930 & three vasodilators in conscious dogs
Lee, King, Clas, Dawn, Gorczyca, William, Silver, Paul, Ezrin, Alan
Published in Journal of molecular and cellular cardiology (01.04.1991)
Published in Journal of molecular and cellular cardiology (01.04.1991)
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4,5-Dihydro-3-(methanesulfonamidophenyl)-1-phenyl-1H-2,4-benzodiazepines: A Novel Class III Antiarrhythmic Agents
Johnson, Robert E, Silver, Paul J, Becker, Russell, Birsner, Nancy C, Bohnet, Eric A, Briggs, G. Maurice, Busacca, Carl A, Canniff, Paul, Carabateas, Philip M, D'Ambra, Thomas, Dundore, Ronald L, Dung, Jen-Sen, Chadwick, Christopher C, Ezrin, Alan M, Gorczyca, William, Habeeb, Peter G, Horan, Patrick, Krafte, Douglas S, Pelling, Gary, O'Connor, Bernard, Saindane, Manohar T, Schlegel, Donald C, Stankus, Gerald P, Swestock, John, Volberg, Walter A
Published in Journal of medicinal chemistry (01.07.1995)
Published in Journal of medicinal chemistry (01.07.1995)
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Compounds, compositions and methods for treating influenza
BAILEY THOMAS R, GORCZYCA WILLIAM P, DIANA GUY D, YOUNG DOROTHY C, NITZ THEODORE J
Year of Publication 07.08.2001
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Year of Publication 07.08.2001
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Compounds, compositions and methods for treating influenza
BAILEY THOMAS R, GORCZYCA WILLIAM P, DIANA GUY D, YOUNG DOROTHY C, NITZ THEODORE J
Year of Publication 30.01.2001
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Year of Publication 30.01.2001
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COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING INFLUENZA
DIANA, GUY, C, BAILEY, THOMAS, R, NITZ, THEODORE, J, GORCZYCA, WILLIAM, P, YOUNG, DOROTHY, C
Year of Publication 06.10.1999
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Year of Publication 06.10.1999
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Compounds, compositions and methods for treating influenza
BAILEY; THOMAS R, YOUNG; DOROTHY C, NITZ; THEODORE J, GORCZYCA; WILLIAM P, DIANA; GUY D
Year of Publication 10.08.1999
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Year of Publication 10.08.1999
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