Toward a Consensus on the Binding Specificity and Promiscuity of PRC2 for RNA
Davidovich, Chen, Wang, Xueyin, Cifuentes-Rojas, Catherine, Goodrich, Karen J., Gooding, Anne R., Lee, Jeannie T., Cech, Thomas R.
Published in Molecular cell (05.02.2015)
Published in Molecular cell (05.02.2015)
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Journal Article
RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells
Long, Yicheng, Hwang, Taeyoung, Gooding, Anne R., Goodrich, Karen J., Rinn, John L., Cech, Thomas R.
Published in Nature genetics (01.09.2020)
Published in Nature genetics (01.09.2020)
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Journal Article
RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure
Lu, Zhipeng, Zhang, Qiangfeng Cliff, Lee, Byron, Flynn, Ryan A., Smith, Martin A., Robinson, James T., Davidovich, Chen, Gooding, Anne R., Goodrich, Karen J., Mattick, John S., Mesirov, Jill P., Cech, Thomas R., Chang, Howard Y.
Published in Cell (19.05.2016)
Published in Cell (19.05.2016)
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Journal Article
Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines
Wang, Xueyin, Goodrich, Karen J., Gooding, Anne R., Naeem, Haroon, Archer, Stuart, Paucek, Richard D., Youmans, Daniel T., Cech, Thomas R., Davidovich, Chen
Published in Molecular cell (16.03.2017)
Published in Molecular cell (16.03.2017)
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Journal Article
The structure of human CST reveals a decameric assembly bound to telomeric DNA
Lim, Ci Ji, Barbour, Alexandra T, Zaug, Arthur J, Goodrich, Karen J, McKay, Allison E, Wuttke, Deborah S, Cech, Thomas R
Published in Science (American Association for the Advancement of Science) (05.06.2020)
Published in Science (American Association for the Advancement of Science) (05.06.2020)
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Journal Article
CST does not evict elongating telomerase but prevents initiation by ssDNA binding
Zaug, Arthur J, Lim, Ci Ji, Olson, Conner L, Carilli, Maria T, Goodrich, Karen J, Wuttke, Deborah S, Cech, Thomas R
Published in Nucleic acids research (18.11.2021)
Published in Nucleic acids research (18.11.2021)
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Journal Article
C9orf72 and triplet repeat disorder RNAs: G-quadruplex formation, binding to PRC2 and implications for disease mechanisms
Wang, Xueyin, Goodrich, Karen J, Conlon, Erin G, Gao, Jianchao, Erbse, Annette H, Manley, James L, Cech, Thomas R
Published in RNA (Cambridge) (01.08.2019)
Published in RNA (Cambridge) (01.08.2019)
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Journal Article
Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2
Long, Yicheng, Bolanos, Ben, Gong, Lihu, Liu, Wei, Goodrich, Karen J, Yang, Xin, Chen, Siming, Gooding, Anne R, Maegley, Karen A, Gajiwala, Ketan S, Brooun, Alexei, Cech, Thomas R, Liu, Xin
Published in eLife (29.11.2017)
Published in eLife (29.11.2017)
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Journal Article
Promiscuous RNA binding by Polycomb repressive complex 2
Davidovich, Chen, Zheng, Leon, Goodrich, Karen J, Cech, Thomas R
Published in Nature structural & molecular biology (01.11.2013)
Published in Nature structural & molecular biology (01.11.2013)
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Journal Article
A dimeric state for PRC2
Davidovich, Chen, Goodrich, Karen J, Gooding, Anne R, Cech, Thomas R
Published in Nucleic acids research (01.08.2014)
Published in Nucleic acids research (01.08.2014)
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Journal Article
Reconstitution of a telomeric replicon organized by CST
Zaug, Arthur J., Goodrich, Karen J., Song, Jessica J., Sullivan, Ashley E., Cech, Thomas R.
Published in Nature (London) (25.08.2022)
Published in Nature (London) (25.08.2022)
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Journal Article
Engineering cis-telomerase RNAs that add telomeric repeats to themselves
Qiao, Feng, Goodrich, Karen J, Cech, Thomas R
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2010)
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Journal Article
RNA recognition by the DNA end-binding Ku heterodimer
Dalby, Andrew B, Goodrich, Karen J, Pfingsten, Jennifer S, Cech, Thomas R
Published in RNA (Cambridge) (01.06.2013)
Published in RNA (Cambridge) (01.06.2013)
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Journal Article
Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13p
Zappulla, David C, Roberts, Jennifer N, Goodrich, Karen J, Cech, Thomas R, Wuttke, Deborah S
Published in Nucleic acids research (01.02.2009)
Published in Nucleic acids research (01.02.2009)
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Journal Article
Tetrahymena telomerase is active as a monomer
Bryan, Tracy M, Goodrich, Karen J, Cech, Thomas R
Published in Molecular biology of the cell (01.12.2003)
Published in Molecular biology of the cell (01.12.2003)
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Journal Article
A Mutant of Tetrahymena Telomerase Reverse Transcriptase with Increased Processivity
Bryan, Tracy M., Goodrich, Karen J., Cech, Thomas R.
Published in The Journal of biological chemistry (04.08.2000)
Published in The Journal of biological chemistry (04.08.2000)
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