Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD
Goodman, Lindsey D., Prudencio, Mercedes, Kramer, Nicholas J., Martinez-Ramirez, Luis F., Srinivasan, Ananth R., Lan, Matthews, Parisi, Michael J., Zhu, Yongqing, Chew, Jeannie, Cook, Casey N., Berson, Amit, Gitler, Aaron D., Petrucelli, Leonard, Bonini, Nancy M.
Published in Nature neuroscience (01.06.2019)
Published in Nature neuroscience (01.06.2019)
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Journal Article
eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS
Goodman, Lindsey D, Prudencio, Mercedes, Srinivasan, Ananth R, Rifai, Olivia M, Lee, Virginia M-Y, Petrucelli, Leonard, Bonini, Nancy M
Published in Acta neuropathologica communications (25.04.2019)
Published in Acta neuropathologica communications (25.04.2019)
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Journal Article
PDPN marks a subset of aggressive and radiation-resistant glioblastoma cells
Modrek, Aram S, Eskilsson, Eskil, Ezhilarasan, Ravesanker, Wang, Qianghu, Goodman, Lindsey D, Ding, Yingwen, Zhang, Ze-Yan, Bhat, Krishna P L, Le, Thanh-Thuy T, Barthel, Floris P, Tang, Ming, Yang, Jie, Long, Lihong, Gumin, Joy, Lang, Frederick F, Verhaak, Roel G W, Aldape, Kenneth D, Sulman, Erik P
Published in Frontiers in oncology (10.08.2022)
Published in Frontiers in oncology (10.08.2022)
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Journal Article
Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies
Berson, Amit, Goodman, Lindsey D, Sartoris, Ashley N, Otte, Charlton G, Aykit, James A, Lee, Virginia M-Y, Trojanowski, John Q, Bonini, Nancy M
Published in Acta neuropathologica communications (29.04.2019)
Published in Acta neuropathologica communications (29.04.2019)
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Journal Article
Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients
Mordes, Daniel A, Prudencio, Mercedes, Goodman, Lindsey D, Klim, Joseph R, Moccia, Rob, Limone, Francesco, Pietilainen, Olli, Chowdhary, Kaitavjeet, Dickson, Dennis W, Rademakers, Rosa, Bonini, Nancy M, Petrucelli, Leonard, Eggan, Kevin
Published in Acta neuropathologica communications (04.07.2018)
Published in Acta neuropathologica communications (04.07.2018)
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Journal Article
Does glial lipid dysregulation alter sleep in Alzheimer’s and Parkinson’s disease?
Goodman, Lindsey D., Moulton, Matthew J., Lin, Guang, Bellen, Hugo J.
Published in Trends in molecular medicine (01.10.2024)
Published in Trends in molecular medicine (01.10.2024)
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Journal Article
Glial lipid droplets resolve ROS during sleep
Goodman, Lindsey D., Moulton, Matthew J., Bellen, Hugo J.
Published in Nature neuroscience (01.04.2024)
Published in Nature neuroscience (01.04.2024)
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Journal Article
Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer’s disease–associated genes
Moulton, Matthew J., Barish, Scott, Ralhan, Isha, Chang, Jinlan, Goodman, Lindsey D., Harland, Jake G., Marcogliese, Paul C., Johansson, Jan O., Ioannou, Maria S., Bellen, Hugo J.
Published in Proceedings of the National Academy of Sciences - PNAS (28.12.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (28.12.2021)
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Journal Article
Autolysosomal exocytosis of lipids protect neurons from ferroptosis
Ralhan, Isha, Chang, Jinlan, Moulton, Matthew J, Goodman, Lindsey D, Lee, Nathanael Y J, Plummer, Greg, Pasolli, H Amalia, Matthies, Doreen, Bellen, Hugo J, Ioannou, Maria S
Published in The Journal of cell biology (05.06.2023)
Published in The Journal of cell biology (05.06.2023)
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Journal Article
Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress
Goodman, Lindsey D., Ralhan, Isha, Li, Xin, Lu, Shenzhao, Moulton, Matthew J., Park, Ye-Jin, Zhao, Pinghan, Kanca, Oguz, Ghaderpour Taleghani, Ziyaneh S., Jacquemyn, Julie, Shulman, Joshua M., Ando, Kanae, Sun, Kai, Ioannou, Maria S., Bellen, Hugo J.
Published in Nature neuroscience (01.10.2024)
Published in Nature neuroscience (01.10.2024)
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Journal Article
Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts
Kramer, Nicholas J., Carlomagno, Yari, Zhang, Yong-Jie, Almeida, Sandra, Cook, Casey N., Gendron, Tania F., Prudencio, Mercedes, Van Blitterswijk, Marka, Belzil, Veronique, Couthouis, Julien, Paul, Joseph West, Goodman, Lindsey D., Daughrity, Lillian, Chew, Jeannie, Garrett, Aliesha, Pregent, Luc, Jansen-West, Karen, Tabassian, Lilia J., Rademakers, Rosa, Boylan, Kevin, Graff-Radford, Neill R., Josephs, Keith A., Parisi, Joseph E., Knopman, David S., Petersen, Ronald C., Boeve, Bradley F., Deng, Ning, Feng, Yanan, Cheng, Tzu-Hao, Dickson, Dennis W., Cohen, Stanley N., Bonini, Nancy M., Link, Christopher D., Gao, Fen-Biao, Petrucelli, Leonard, Gitler, Aaron D.
Published in Science (American Association for the Advancement of Science) (12.08.2016)
Published in Science (American Association for the Advancement of Science) (12.08.2016)
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Journal Article
Author Correction: Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD
Goodman, Lindsey D., Prudencio, Mercedes, Kramer, Nicholas J., Martinez-Ramirez, Luis F., Srinivasan, Ananth R., Lan, Matthews, Parisi, Michael J., Zhu, Yongqing, Chew, Jeannie, Cook, Casey N., Berson, Amit, Gitler, Aaron D., Petrucelli, Leonard, Bonini, Nancy M.
Published in Nature neuroscience (01.03.2023)
Published in Nature neuroscience (01.03.2023)
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Journal Article
ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts
Yuan, Alice L, Ricks, Christian B, Bohm, Alexandra K, Lun, Xueqing, Maxwell, Lori, Safdar, Shahana, Bukhari, Shazreh, Gerber, Amanda, Sayeed, Wajid, Bering, Elizabeth A, Pedersen, Haley, Chan, Jennifer A, Shen, Yaoqing, Marra, Marco, Kaplan, David R, Mason, Warren, Goodman, Lindsey D, Ezhilarasan, Ravesanker, Kaufmann, Ascher B, Cabral, Matthew, Robbins, Steve M, Senger, Donna L, Cahill, Daniel P, Sulman, Erik P, Cairncross, J Gregory, Blough, Michael D
Published in PloS one (28.08.2018)
Published in PloS one (28.08.2018)
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Journal Article
A gene expression signature predicts recurrence-free survival in meningioma
Olar, Adriana, Goodman, Lindsey D, Wani, Khalida M, Boehling, Nicholas S, Sharma, Devi S, Mody, Reema R, Gumin, Joy, Claus, Elizabeth B, Lang, Frederick F, Cloughesy, Timothy F, Lai, Albert, Aldape, Kenneth D, DeMonte, Franco, Sulman, Erik P
Published in Oncotarget (23.03.2018)
Published in Oncotarget (23.03.2018)
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Journal Article
A fly model for the CCUG-repeat expansion of myotonic dystrophy type 2 reveals a novel interaction with MBNL1
Yu, Zhenming, Goodman, Lindsey D, Shieh, Shin-Yi, Min, Michelle, Teng, Xiuyin, Zhu, Yongqing, Bonini, Nancy M
Published in Human molecular genetics (15.02.2015)
Published in Human molecular genetics (15.02.2015)
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Journal Article
THE TREATMENT-RESISTANT MESENCHYMAL SIGNATURE IN GLIOBLASTOMA DERIVES FROM TUMOR CELLS INDEPENDENT OF STROMA
Sulman, E. P., Wang, Q., Ezhilarasan, R., Goodman, L. D., Gumen, J., Sun, P., Aldape, K., Alfred Yung, W., Heffernan, T., Draetta, G. F., Lang, F. F.
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2014)
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Journal Article
Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma
Bhat, Krishna P.L., Balasubramaniyan, Veerakumar, Vaillant, Brian, Ezhilarasan, Ravesanker, Hummelink, Karlijn, Hollingsworth, Faith, Wani, Khalida, Heathcock, Lindsey, James, Johanna D., Goodman, Lindsey D., Conroy, Siobhan, Long, Lihong, Lelic, Nina, Wang, Suzhen, Gumin, Joy, Raj, Divya, Kodama, Yoshinori, Raghunathan, Aditya, Olar, Adriana, Joshi, Kaushal, Pelloski, Christopher E., Heimberger, Amy, Kim, Se Hoon, Cahill, Daniel P., Rao, Ganesh, Den Dunnen, Wilfred F.A., Boddeke, Hendrikus W.G.M., Phillips, Heidi S., Nakano, Ichiro, Lang, Frederick F., Colman, Howard, Sulman, Erik P., Aldape, Kenneth
Published in Cancer cell (09.09.2013)
Published in Cancer cell (09.09.2013)
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