Breast cancers utilize hypoxic glycogen stores via PYGB, the brain isoform of glycogen phosphorylase, to promote metastatic phenotypes
Altemus, Megan A, Goo, Laura E, Little, Andrew C, Yates, Joel A, Cheriyan, Hannah G, Wu, Zhi Fen, Merajver, Sofia D
Published in PloS one (19.09.2019)
Published in PloS one (19.09.2019)
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Journal Article
IL-4/IL-13 Stimulated Macrophages Enhance Breast Cancer Invasion Via Rho-GTPase Regulation of Synergistic VEGF/CCL-18 Signaling
Little, Andrew C, Pathanjeli, Pragathi, Wu, Zhifen, Bao, Liwei, Goo, Laura E, Yates, Joel A, Oliver, C Ryan, Soellner, Matthew B, Merajver, Sofia D
Published in Frontiers in oncology (31.05.2019)
Published in Frontiers in oncology (31.05.2019)
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Journal Article
RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers
Abraham, Hannah G., Ulintz, Peter J., Goo, Laura, Yates, Joel A., Little, Andrew C., Bao, Liwei, Wu, Zhifen, Merajver, Sofia D.
Published in Frontiers in oncology (26.08.2021)
Published in Frontiers in oncology (26.08.2021)
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Journal Article
Abstract 2616: RhoC decreases tight junction stabilization in breast cancer cells, revealing a potential therapeutic target
Abraham, Hannah, Goo, Laura, Little, Andrew, Yates, Joel, Wu, Zhifen, Merajver, Sofia D.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Precision medicine-based platform to guide the treatment of EML4-ALK driven lung cancers and other NSCLC in real time
Merajver, Sofia Diana, Udager, Aaron M, Qin, Angel, Lagisetty, Kiran, Bao, Liwei, Cheng, Xu, Madhi, Hamadi, Goo, Laura, Kathawate, Varun, Ulintz, Peter, Liu, Albert, Serhan, Habib, Navani, Vishal, Jefferies, John L., Ali, Muhammad Sajawal, Monument, Michael, Kratz, Johannes Ruediger, Smith, Amber, Soellner, Matthew, Merrill, Nathan
Published in Journal of clinical oncology (10.08.2024)
Published in Journal of clinical oncology (10.08.2024)
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Journal Article
Abstract 1444: RhoC regulation of inflammatory breast cancer metabolism
Goo, Laura E., Yates, Joel A., Bao, Liwei, Wu, Zhifen, Merajver, Sofia D.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 4518: IL-4/IL-13 stimulated tumor-associated macrophages enhance breast cancer cell invasion through Rho-GTPase signaling
Little, Andrew C., Pathanjeli, Pragathi, Wu, Zhifen, Bao, Liwei, Goo, Laura, Yates, Joel A., Merajver, Sofia D.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Norstictic Acid Is a Selective Allosteric Transcriptional Regulator
Garlick, Julie M, Sturlis, Steven M, Bruno, Paul A, Yates, Joel A, Peiffer, Amanda L, Liu, Yejun, Goo, Laura, Bao, LiWei, De Salle, Samantha N, Tamayo-Castillo, Giselle, Brooks, Charles L, Merajver, Sofia D, Mapp, Anna K
Published in Journal of the American Chemical Society (30.06.2021)
Published in Journal of the American Chemical Society (30.06.2021)
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Journal Article
Integrative Drug Screening and Multiomic Characterization of Patient-derived Bladder Cancer Organoids Reveal Novel Molecular Correlates of Gemcitabine Response
Merrill, Nathan M, Kaffenberger, Samuel D, Bao, Liwei, Vandecan, Nathalie, Goo, Laura, Apfel, Athena, Cheng, Xu, Qin, Zhaoping, Liu, Chia-Jen, Bankhead, Armand, Wang, Yin, Kathawate, Varun, Tudrick, Lila, Serhan, Habib A, Farah, Zackariah, Ellimoottil, Chad, Hafez, Khaled S, Herrel, Lindsey A, Montgomery, Jeffrey S, Morgan, Todd M, Salami, Simpa S, Weizer, Alon Z, Ulintz, Peter J, Day, Mark L, Soellner, Matthew B, Palmbos, Phillip L, Merajver, Sofia D, Udager, Aaron M
Published in European urology (17.08.2024)
Published in European urology (17.08.2024)
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Journal Article
High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions
Little, Andrew Charles, Kovalenko, Ilya, Goo, Laura Elaine, Hong, Hanna Sungok, Kerk, Samuel Andrew, Yates, Joel Anthony, Purohit, Vinee, Lombard, David Benner, Merajver, Sofia Diana, Lyssiotis, Costas Andreas
Published in Communications biology (29.05.2020)
Published in Communications biology (29.05.2020)
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Journal Article
Abstract 4363: Effects of the small GTPase RhoC on inflammatory breast cancer metabolism
Goo, Laura E., Yates, Joel A., Little, Andrew C., Kremer, Daniel, Kovalenko, Ilya, Oliver, Christopher R., Westerhof, Trisha, Wu, Zhifen, Vandecan, Nathalie, Bao, Liwei, Ulintz, Peter J., Lyssiotis, Costas A., Merajver, Sofia D.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Precision medicine-based platform to guide the treatment of EML4-ALK fusion lung cancers and other non-small cell lung cancers
Merrill, Nathan, Udager, Aaron M., Qin, Angel, Lagisetty, Kiran, Aikins, Marisa, Bao, Liwei, Cheng, Xu, Goo, Laura, Kathawate, Varun, Vandenburg, Bryce, Ulintz, Peter, Qin, Zhaoping, Liu, Albert, Serhan, Habib, Nagrath, Sunitha, Hsu, Peggy, Soellner, Matthew, Merajver, Sofia
Published in JCO global oncology (01.08.2023)
Published in JCO global oncology (01.08.2023)
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Journal Article
Abstract 5592: Expansion and characterization on ALK positive NSCLC circulating tumor cells isolated using a size based inertial microfluidic Labyrinth device
Chen, Yuru, Fouladdel, Shamileh, Ball, Harrison, Cheng, Xu, Bao, Liwei, Serhan, Habib, Liu, Albert, Vandenburg, Bryce, Goo, Laura, Merrill, Nathan, Udager, Aaron, Qin, Angel, Merajver, Sofia D., Nagrath, Sunitha
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 223: Precision medicine-based platform to guide the treatment of EML4-ALK fusion lung cancers and other NSCLC
Merrill, Nathan M., Udager, Aaron, Qin, Angel, Lagisetty, Kiran, Bao, Liwei, Cheng, Xu, Madhi, Hamadi, Banerjee, Ananya, Jahromi, Marziyeh Salehi, Goo, Laura, Kathawate, Varun, Vandenburg, Bryce, Aikins, Marisa, Slayton, Mark, Ulintz, Peter, Qin, Zhaoping, Liu, Chia-jen, Serhan, Habib, Jefferies, John, Ali, Muhammad Sajawal, Navani, Vishal, Monument, Michael, Kratz, Johannes, Smith, Amber, Chang, Andrew, Kalemkerian, Gregory, Nagrath, Sunitha, Hsu, Peggy, Soellner, Matthew B., Merajver, Sofia D.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract A009: Integrative drug screening and multi-omic characterization of patient-derived bladder cancer organoids reveals novel molecular correlates of chemotherapy response
Merrill, Nathan M., Kaffenberger, Samuel D., Bao, Liwei, Vandecan, Nathalie, Goo, Laura E., Apfel, Athena, Cheng, Xu, Qin, Zhaoping, Liu, Chia-Jen, Bankhead, Armand, Wang, Yin, Kathawate, Varun, Tudrick, Lila, Serhan, Habib, Farah, Zackariah, Ellimoottil, Chad, Hafez, Khaled S., Herrel, Lindsey A., Montgomery, Jeffrey S., Morgan, Todd M., Salami, Simpa S., Weizer, Alon Z., Ulintz, Peter J., Day, Mark L., Soellner, Matthew B., Palmbos, Phillip L., Merajver, Sofia D., Udager, Aaron M.
Published in Clinical cancer research (17.05.2024)
Published in Clinical cancer research (17.05.2024)
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Journal Article
Abstract 3072: Functional assays of drug sensitivity in real-time from patient material for precision oncology in bladder cancer
Merrill, Nathan M., Bao, Liwei, Cheng, Xu, Vandecan, Nathalie, Qin, Zhaoping, Liu, Albert, Apfel, Athena, Goo, Laura, Tudrick, Lila, Bankhead, Armand, Palmbos, Phil, Kaffenberger, Samuel, Hafez, Khaled, Montgomery, Jeffrey, Morgan, Todd, Alva, Ajjai, Udager, Aaron, Soellner, Matthew, Merajver, Sofia
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Norstictic acid is a selective allosteric transcriptional regulator
Garlick, Julie M, Sturlis, Steven M, Bruno, Paul A, Yates, Joel A, Peiffer, Amanda L, Liu, Yejun, Goo, Laura, Bao, Liwei, De Salle, Samantha N, Tamayo-Castillo, Giselle, Brooks, Charles L, Merajver, Sofia D, Mapp, Anna K
Published in bioRxiv (26.03.2021)
Published in bioRxiv (26.03.2021)
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Paper
Integration of high-content fluorescence imaging into the metabolic flux assay reveals insights into mitochondrial properties and functions
Little, Andrew C, Kovalenko, Ilya, Goo, Laura E, Hong, Hanna S, Kerk, Samuel A, Yates, Joel A, Purohit, Vinee, Lombard, David B, Merajver, Sofia D, Lyssiotis, Costas A
Published in bioRxiv (04.09.2019)
Published in bioRxiv (04.09.2019)
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Paper