Supplementation with Docosahexaenoic Acid and Extra Virgin Olive Oil Prevents Liver Steatosis Induced by a High‐Fat Diet in Mice through PPAR‐α and Nrf2 Upregulation with Concomitant SREBP‐1c and NF‐kB Downregulation
Hernández‐Rodas, María C., Valenzuela, Rodrigo, Echeverría, Francisca, Rincón‐Cervera, Miguel Ángel, Espinosa, Alejandra, Illesca, Paola, Muñoz, Patricio, Corbari, Alicia, Romero, Nalda, Gonzalez‐Mañan, Daniel, Videla, Luis A.
Published in Molecular nutrition & food research (01.12.2017)
Published in Molecular nutrition & food research (01.12.2017)
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High-fat diet induces mouse liver steatosis with a concomitant decline in energy metabolism: attenuation by eicosapentaenoic acid (EPA) or hydroxytyrosol (HT) supplementation and the additive effects upon EPA and HT co-administration
Echeverría, Francisca, Valenzuela, Rodrigo, Bustamante, Andrés, Álvarez, Daniela, Ortiz, Macarena, Espinosa, Alejandra, Illesca, Paola, Gonzalez-Mañan, Daniel, Videla, Luis A
Published in Food & function (01.09.2019)
Published in Food & function (01.09.2019)
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N‐3 long‐chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation in relation to PPAR‐α upregulation and NF‐κB DNA binding abrogation
Tapia, Gladys, Valenzuela, Rodrigo, Espinosa, Alejandra, Romanque, Pamela, Dossi, Camila, Gonzalez‐Mañán, Daniel, Videla, Luis A, D'Espessailles, Amanda
Published in Molecular nutrition & food research (01.06.2014)
Published in Molecular nutrition & food research (01.06.2014)
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Docosahexaenoic acid and hydroxytyrosol co‐administration fully prevents liver steatosis and related parameters in mice subjected to high‐fat diet: A molecular approach
Soto‐Alarcón, Sandra A., Ortiz, Macarena, Orellana, Paula, Echeverría, Francisca, Bustamante, Andrés, Espinosa, Alejandra, Illesca, Paola, Gonzalez‐Mañán, Daniel, Valenzuela, Rodrigo, Videla, Luis A.
Published in BioFactors (Oxford) (01.11.2019)
Published in BioFactors (Oxford) (01.11.2019)
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Molecular mechanisms related to the hepatoprotective effects of antioxidant-rich extra virgin olive oil supplementation in rats subjected to short-term iron administration
Barrera, Cynthia, Valenzuela, Rodrigo, Rincón, Miguel Ángel, Espinosa, Alejandra, Echeverria, Francisca, Romero, Nalda, Gonzalez-Mañan, Daniel, Videla, Luis A.
Published in Free radical biology & medicine (01.10.2018)
Published in Free radical biology & medicine (01.10.2018)
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Dietary alpha- and gamma-tocopherol (1:5 ratio) supplementation attenuates adipose tissue expansion, hepatic steatosis, and expression of inflammatory markers in a high-fat-diet–fed murine model
Juretić, Nevenka, Sepúlveda, Ruth, D'Espessailles, Amanda, Vera, Daniela B., Cadagan, Cynthia, de Miguel, Manuel, González-Mañán, Daniel, Tapia, Gladys
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01.05.2021)
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01.05.2021)
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Iron-induced derangement in hepatic Δ-5 and Δ-6 desaturation capacity and fatty acid profile leading to steatosis: Impact on extrahepatic tissues and prevention by antioxidant-rich extra virgin olive oil
Barrera, Cynthia, Valenzuela, Rodrigo, Rincón, Miguel A., Espinosa, Alejandra, López-Arana, Sandra, González-Mañan, Daniel, Romero, Nalda, Vargas, Romina, Videla, Luis A.
Published in Prostaglandins, leukotrienes and essential fatty acids (01.02.2020)
Published in Prostaglandins, leukotrienes and essential fatty acids (01.02.2020)
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Role of dietary α- and γ-tocopherol from Rosa mosqueta oil in the prevention of alterations induced by high-fat diet in a murine model
Tapia, Gladys, Silva, David, Romero, Nalda, Pettinelli, Paulina, Dossi, Camila G., de Miguel, Manuel, González-Mañán, Daniel
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01.09.2018)
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01.09.2018)
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Journal Article
N-3 long-chain polyunsaturated fatty acid supplementation significantly reduces liver oxidative stress in high fat induced steatosis
Valenzuela, Rodrigo, Espinosa, Alejandra, González-Mañán, Daniel, D'Espessailles, Amanda, Fernández, Virginia, Videla, Luis A, Tapia, Gladys
Published in PloS one (17.10.2012)
Published in PloS one (17.10.2012)
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Bioconversion of α-linolenic acid to n-3 LCPUFA and expression of PPAR-alpha, acyl coenzyme A oxidase 1 and carnitine acyl transferase I are incremented after feeding rats with α-linolenic acid-rich oils
González-Mañán, Daniel, Tapia, Gladys, Gormaz, Juan Guillermo, D'Espessailles, Amanda, Espinosa, Alejandra, Masson, Lilia, Varela, Patricia, Valenzuela, Alfonso, Valenzuela, Rodrigo
Published in Food & function (01.07.2012)
Published in Food & function (01.07.2012)
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Increase in endogenous estradiol in the progeny of obese rats is associated with precocious puberty and altered follicular development in adulthood
Ambrosetti, Valery, Guerra, Marcelo, Ramírez, Luisa A., Reyes, Aldo, Álvarez, Daniela, Olguín, Sofía, González-Mañan, Daniel, Fernandois, Daniela, Sotomayor-Zárate, Ramón, Cruz, Gonzalo
Published in Endocrine (01.07.2016)
Published in Endocrine (01.07.2016)
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Rosa Mosqueta Oil Prevents Oxidative Stress and Inflammation through the Upregulation of PPAR-α and NRF2 in C57BL/6J Mice Fed a High-Fat Diet
González-Mañán, Daniel, D'Espessailles, Amanda, Dossi, Camila G, San Martín, Marcela, Mancilla, Rodrigo A, Tapia, Gladys S
Published in The Journal of nutrition (01.04.2017)
Published in The Journal of nutrition (01.04.2017)
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Journal Article
Effects of rosa mosqueta oil supplementation in lipogenic markers associated with prevention of liver steatosis
Dossi, Camila G, Cadagan, Cynthia, San Martín, Marcela, Espinosa, Alejandra, González-Mañán, Daniel, Silva, David, Mancilla, Rodrigo A, Tapia, Gladys S
Published in Food & function (01.02.2017)
Published in Food & function (01.02.2017)
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Journal Article
Prevention of liver steatosis through fish oil supplementation: correlation of oxidative stress with insulin resistance and liver fatty acid content
Espinosa, Alejandra, Valenzuela, Rodrigo, González-Mañán, Daniel, D'Espessailles, Amanda, Guillermo Gormaz, Juan, Barrera, Cynthia, Tapia, Gladys
Published in Archivos latinoamericanos de nutrición (01.03.2013)
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Published in Archivos latinoamericanos de nutrición (01.03.2013)
Journal Article
N-3 long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation in relation to PPAR-[alpha] upregulation and NF-[kappa]B DNA binding abrogation
Tapia, Gladys, Valenzuela, Rodrigo, Espinosa, Alejandra, Romanque, Pamela, Dossi, Camila, Gonzalez-Manan, Daniel, Videla, Luis A, D'Espessailles, Amanda
Published in Molecular nutrition & food research (01.06.2014)
Published in Molecular nutrition & food research (01.06.2014)
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Journal Article
N-3 long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation in relation to PPAR-α upregulation and NF-KB DNA binding abrogation
TAPIA, Gladys, VALENZUELA, Rodrigo, ESPINOSA, Alejandra, ROMANQUE, Pamela, DOSSI, Camila, GONZALEZ-MANAN, Daniel, VIDELA, Luis A, D'ESPESSAILLES, Amanda
Published in Molecular nutrition & food research (2014)
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Published in Molecular nutrition & food research (2014)
Journal Article
P 017 - Changes in expression of NLRP3 inflammasome components and oxidative parameters of mice subjected to high-fat diet and rosa mosqueta oil supplementation
González-Mañán, Daniel, Dossi, Camila, Tapia, Gladys
Published in Free radical biology & medicine (01.07.2017)
Published in Free radical biology & medicine (01.07.2017)
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