Impact of the Recognition Part of Dipeptidyl Nitroalkene Compounds on the Inhibition Mechanism of Cysteine Proteases Cruzain and Cathepsin L
Arafet, Kemel, Royo, Santiago, Schirmeister, Tanja, Barthels, Fabian, González, Florenci V., Moliner, Vicent
Published in ACS catalysis (05.05.2023)
Published in ACS catalysis (05.05.2023)
Get full text
Journal Article
Nitroepoxides as Versatile Precursors to 1,4-Diamino Heterocycles
Vidal-Albalat, Andreu, Rodriguez, Santiago, Gonzalez, Florenci V.
Published in Organic letters (21.03.2014)
Published in Organic letters (21.03.2014)
Get full text
Journal Article
Regioselective Opening of Nitroepoxides with Unsymmetrical Diamines
Nosood, Yazdanbakhsh L, Ziyaei Halimehjani, Azim, González, Florenci V
Published in Journal of organic chemistry (02.02.2018)
Published in Journal of organic chemistry (02.02.2018)
Get full text
Journal Article
Regioselective Ring Opening and Isomerization Reactions of 3,4-Epoxyesters Catalyzed by Boron Trifluoride
Izquierdo, Javier, Rodríguez, Santiago, González, Florenci V
Published in Organic letters (05.08.2011)
Published in Organic letters (05.08.2011)
Get full text
Journal Article
Dynamic Kinetic Asymmetric Ring-Opening/Reductive Amination Sequence of Racemic Nitroepoxides with Chiral Amines: Enantioselective Synthesis of Chiral Vicinal Diamines
Agut, Juan, Vidal, Andreu, Rodríguez, Santiago, González, Florenci V
Published in Journal of organic chemistry (07.06.2013)
Published in Journal of organic chemistry (07.06.2013)
Get full text
Journal Article
Dipeptidyl Enoates As Potent Rhodesain Inhibitors That Display a Dual Mode of Action
Royo, Santiago, Rodríguez, Santiago, Schirmeister, Tanja, Kesselring, Jochen, Kaiser, Marcel, González, Florenci V.
Published in ChemMedChem (01.09.2015)
Published in ChemMedChem (01.09.2015)
Get full text
Journal Article
Peptidyl nitroalkene inhibitors of main protease rationalized by computational and crystallographic investigations as antivirals against SARS-CoV-2
Medrano, Francisco J., de la Hoz-Rodríguez, Sergio, Martí, Sergio, Arafet, Kemel, Schirmeister, Tanja, Hammerschmidt, Stefan J., Müller, Christin, González-Martínez, Águeda, Santillana, Elena, Ziebuhr, John, Romero, Antonio, Zimmer, Collin, Weldert, Annabelle, Zimmermann, Robert, Lodola, Alessio, Świderek, Katarzyna, Moliner, Vicent, González, Florenci V.
Published in Communications chemistry (18.01.2024)
Published in Communications chemistry (18.01.2024)
Get full text
Journal Article
Formal [3+2] Cycloaddition Reactions of Electron-Rich Aryl Epoxides with Alkenes under Lewis Acid Catalysis Affording Tetrasubstituted Tetrahydrofurans
Macías-Villamizar, Víctor E, Cuca-Suárez, Luís, Rodríguez, Santiago, González, Florenci V
Published in Molecules (Basel, Switzerland) (06.02.2020)
Published in Molecules (Basel, Switzerland) (06.02.2020)
Get full text
Journal Article
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7
Gütschow, Michael, Eynde, Jean Jacques Vanden, Jampilek, Josef, Kang, CongBao, Mangoni, Arduino A, Fossa, Paola, Karaman, Rafik, Trabocchi, Andrea, Scott, Peter J H, Reynisson, Jóhannes, Rapposelli, Simona, Galdiero, Stefania, Winum, Jean-Yves, Brullo, Chiara, Prokai-Tatrai, Katalin, Sharma, Arun K, Schapira, Matthieu, Azuma, Yasu-Taka, Cerchia, Laura, Spetea, Mariana, Torri, Giangiacomo, Collina, Simona, Geronikaki, Athina, García-Sosa, Alfonso T, Vasconcelos, M Helena, Sousa, Maria Emília, Kosalec, Ivan, Tuccinardi, Tiziano, Duarte, Iola F, Salvador, Jorge A R, Bertinaria, Massimo, Pellecchia, Maurizio, Amato, Jussara, Rastelli, Giulio, Gomes, Paula A C, Guedes, Rita C, Sabatier, Jean-Marc, Estévez-Braun, Ana, Pagano, Bruno, Mangani, Stefano, Ragno, Rino, Kokotos, George, Brindisi, Margherita, González, Florenci V, Borges, Fernanda, Miloso, Mariarosaria, Rautio, Jarkko, Muñoz-Torrero, Diego
Published in Molecules (Basel, Switzerland) (28.06.2020)
Published in Molecules (Basel, Switzerland) (28.06.2020)
Get full text
Journal Article
Mechanism of inhibition of SARS-CoV-2 Mpro by N3 peptidyl Michael acceptor explained by QM/MM simulations and design of new derivatives with tunable chemical reactivity
Arafet, Kemel, Serrano-Aparicio, Natalia, Lodola, Alessio, Mulholland, Adrian J, González, Florenci V, Świderek, Katarzyna, Moliner, Vicent
Published in Chemical Science (27.11.2020)
Published in Chemical Science (27.11.2020)
Get full text
Journal Article
Web Resource
Lignoids Isolated from Nectandra turbacensis (Kunth) Nees (Lauraceae)
Macías-Villamizar, Víctor, Cuca-Suárez, Luís, González, Florenci V, Rodríguez, Santiago
Published in Records of natural products (01.01.2016)
Get full text
Published in Records of natural products (01.01.2016)
Journal Article
Profiling Cysteine Proteases Activities in Neuroinflammatory Cells
González Adelantado, Florenci Vicent, Agost-Beltrán, Laura, Canseco-Rodriguez, Ania, Schirmeister, Tanja, Rodríguez, Santiago, Sánchez-Pérez, Ana María, Canseco-Rodríguez, Ania, González, Florenci V
Published in ChemMedChem (30.10.2024)
Published in ChemMedChem (30.10.2024)
Get full text
Journal Article
Impact of the Warhead of Dipeptidyl Keto Michael Acceptors on the Inhibition Mechanism of Cysteine Protease Cathepsin L
Fernández-de-la-Pradilla, Adrián, Royo, Santiago, Schirmeister, Tanja, Barthels, Fabian, Świderek, Katarzyna, González, Florenci V., Moliner, Vicent
Published in ACS catalysis (20.10.2023)
Published in ACS catalysis (20.10.2023)
Get full text
Journal Article
Investigation of the Compatibility between Warheads and Peptidomimetic Sequences of Protease Inhibitors-A Comprehensive Reactivity and Selectivity Study
Müller, Patrick, Meta, Mergim, Meidner, Jan Laurenz, Schwickert, Marvin, Meyr, Jessica, Schwickert, Kevin, Kersten, Christian, Zimmer, Collin, Hammerschmidt, Stefan Josef, Frey, Ariane, Lahu, Albin, de la Hoz-Rodríguez, Sergio, Agost-Beltrán, Laura, Rodríguez, Santiago, Diemer, Kira, Neumann, Wilhelm, Gonzàlez, Florenci V, Engels, Bernd, Schirmeister, Tanja
Published in International journal of molecular sciences (01.04.2023)
Published in International journal of molecular sciences (01.04.2023)
Get full text
Journal Article