Crystal structure and molecular dynamics simulations of a promiscuous ancestor reveal residues and an epistatic interaction involved in substrate binding and catalysis in the ATP‐dependent vitamin kinase family members
Gonzalez‐Ordenes, Felipe, Bravo‐Moraga, Felipe, Gonzalez, Evelin, Hernandez‐Cabello, Leslie, Alzate‐Morales, Jans, Guixé, Victoria, Castro‐Fernandez, Victor
Published in Protein science (01.04.2021)
Published in Protein science (01.04.2021)
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Kinetic characterization and phylogenetic analysis of human ADP-dependent glucokinase reveal new insights into its regulatory properties
Herrera-Morandé, Alejandra, Vallejos-Baccelliere, Gabriel, Cea, Pablo A., Zamora, Ricardo A., Cid, Dixon, Maturana, Pablo, González-Ordenes, Felipe, Castro-Fernández, Víctor, Guixé, Victoria
Published in Archives of biochemistry and biophysics (01.06.2023)
Published in Archives of biochemistry and biophysics (01.06.2023)
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ADP-Dependent Kinases From the Archaeal Order Methanosarcinales Adapt to Salt by a Non-canonical Evolutionarily Conserved Strategy
Gonzalez-Ordenes, Felipe, Cea, Pablo A, Fuentes-Ugarte, Nicolás, Muñoz, Sebastián M, Zamora, Ricardo A, Leonardo, Diego, Garratt, Richard C, Castro-Fernandez, Victor, Guixé, Victoria
Published in Frontiers in microbiology (26.06.2018)
Published in Frontiers in microbiology (26.06.2018)
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Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases
Castro-Fernandez, Víctor, Herrera-Morande, Alejandra, Zamora, Ricardo, Merino, Felipe, Gonzalez-Ordenes, Felipe, Padilla-Salinas, Felipe, Pereira, Humberto M., Brandão-Neto, Jose, Garratt, Richard C., Guixe, Victoria
Published in The Journal of biological chemistry (22.09.2017)
Published in The Journal of biological chemistry (22.09.2017)
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Journal Article
Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases
Castro-Fernandez, Víctor, Herrera-Morande, Alejandra, Zamora, Ricardo, Merino, Felipe, Gonzalez-Ordenes, Felipe, Padilla-Salinas, Felipe, Pereira, Humberto M., Brandão-Neto, Jose, Garratt, Richard C., Guixe, Victoria
Published in The Journal of biological chemistry (22.12.2017)
Published in The Journal of biological chemistry (22.12.2017)
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Journal Article