Search Results - "Gontarewicz, Artur" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Inhibition of IL‐6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer

Inhibition of IL‐6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer

by Goumas, Freya A., Holmer, Reinhild, Egberts, Jan‐Hendrik, Gontarewicz, Artur, Heneweer, Carola, Geisen, Ulf, Hauser, Charlotte, Mende, Maria‐Margarete, Legler, Karen, Röcken, Christoph, Becker, Thomas, Waetzig, Georg H., Rose‐John, Stefan, Kalthoff, Holger
Published in International journal of cancer (01.09.2015)

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Whole-slide image analysis of the tumor microenvironment identifies low B-cell content as a predictor of adverse outcome in patients with advanced-stage classical Hodgkin lymphoma treated with BEACOPP

Whole-slide image analysis of the tumor microenvironment identifies low B-cell content as a predictor of adverse outcome in patients with advanced-stage classical Hodgkin lymphoma treated with BEACOPP

by Jachimowicz, Ron Daniel, Pieper, Luise, Reinke, Sarah, Gontarewicz, Artur, Plütschow, Annette, Haverkamp, Heinz, Frauenfeld, Leonie, Fend, Falko, Overkamp, Mathis, Jochims, Franziska, Thorns, Christoph, Leo Hansmann, Martin, Möller, Peter, Rosenwald, Andreas, Stein, Harald, Reinhardt, Hans Christian, Borchmann, Peter, von Tresckow, Bastian, Engert, Andreas, Klapper, Wolfram
Published in Haematologica (Roma) (01.06.2021)

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Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I

Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I

by Gontarewicz, Artur, Balabanov, Stefan, Keller, Gunhild, Colombo, Riccardo, Graziano, Alessio, Pesenti, Enrico, Benten, Daniel, Bokemeyer, Carsten, Fiedler, Walter, Moll, Jürgen, Brümmendorf, Tim H.
Published in Blood (15.04.2008)

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Danusertib (formerly PHA-739358)--a novel combined pan-Aurora kinases and third generation Bcr-Abl tyrosine kinase inhibitor

Danusertib (formerly PHA-739358)--a novel combined pan-Aurora kinases and third generation Bcr-Abl tyrosine kinase inhibitor

by Gontarewicz, Artur, Brümmendorf, Tim H
Published in Recent results in cancer research (01.01.2010)

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Aurora Kinase Inhibitor PHA-739358 Suppresses Growth of Hepatocellular Carcinoma In Vitro and in a Xenograft Mouse Model

Aurora Kinase Inhibitor PHA-739358 Suppresses Growth of Hepatocellular Carcinoma In Vitro and in a Xenograft Mouse Model

by Benten, Daniel, Keller, Gunhild, Quaas, Alexander, Schrader, Jorg, Gontarewicz, Artur, Balabanov, Stefan, Braig, Melanie, Wege, Henning, Moll, Jurgen, Lohse, Ansgar W., Brummendorf, Tim H.
Published in Neoplasia (New York, N.Y.) (01.09.2009)

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Abcg2 overexpression represents a novel mechanism for acquired resistance to the multi-kinase inhibitor Danusertib in BCR-ABL-positive cells in vitro

Abcg2 overexpression represents a novel mechanism for acquired resistance to the multi-kinase inhibitor Danusertib in BCR-ABL-positive cells in vitro

by Balabanov, Stefan, Gontarewicz, Artur, Keller, Gunhild, Raddrizzani, Laura, Braig, Melanie, Bosotti, Roberta, Moll, Jürgen, Jost, Edgar, Barett, Christine, Rohe, Imke, Bokemeyer, Carsten, Holyoake, Tessa L, Brümmendorf, Tim H
Published in PloS one (26.04.2011)

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Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL–positive leukemias identified by a proteomics approach

Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL–positive leukemias identified by a proteomics approach

by Balabanov, Stefan, Gontarewicz, Artur, Ziegler, Patrick, Hartmann, Ulrike, Kammer, Winfried, Copland, Mhairi, Brassat, Ute, Priemer, Martin, Hauber, Ilona, Wilhelm, Thomas, Schwarz, Gerold, Kanz, Lothar, Bokemeyer, Carsten, Hauber, Joachim, Holyoake, Tessa L., Nordheim, Alfred, Brümmendorf, Tim H.
Published in Blood (15.02.2007)

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Abundant expression of mTOR kinase in salivary gland tumors - potentials as therapy target?

Abundant expression of mTOR kinase in salivary gland tumors - potentials as therapy target?

by Clauditz, Till Sebastian, Gontarewicz, Artur, Bokemeyer, Carsten, Sauter, Guido, Knecht, Rainald, Münscher, Adrian, Wilczak, Waldemar
Published in Journal of oral pathology & medicine (01.11.2013)

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The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNγ-induced cell death in human ovarian carcinoma cells

The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNγ-induced cell death in human ovarian carcinoma cells

by SERS, Christine, HUSMANN, Knut, NAZARENKO, Irina, REICH, Steffen, KAI WIECHEN, ZHUMABAYEVA, Bakhyt, ADHIKARI, Punam, SCHRÖDER, Katharina, GONTAREWICZ, Artur, SCHÄFER, Reinhold
Published in Oncogene (25.04.2002)

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Suppression of the TIG3 tumor suppressor gene in human ovarian carcinomas is mediated via mitogen‐activated kinase‐dependent and ‐independent mechanisms

Suppression of the TIG3 tumor suppressor gene in human ovarian carcinomas is mediated via mitogen‐activated kinase‐dependent and ‐independent mechanisms

by Lotz, Kristina, Kellner, Tobias, Heitmann, Michaela, Nazarenko, Irina, Noske, Aurelia, Malek, Anastassia, Gontarewicz, Artur, Schäfer, Reinhold, Sers, Christine
Published in International journal of cancer (10.10.2005)

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Spindle-Cell Variants of Primary Cutaneous Follicle Center B-Cell Lymphomas Are Germinal Center B-Cell Lymphomas by Gene Expression Profiling Using a Formalin-Fixed Paraffin-Embedded Specimen

Spindle-Cell Variants of Primary Cutaneous Follicle Center B-Cell Lymphomas Are Germinal Center B-Cell Lymphomas by Gene Expression Profiling Using a Formalin-Fixed Paraffin-Embedded Specimen

by Oschlies, Ilske, Kohler, Christian W., Szczepanowski, Monika, Koch, Karoline, Gontarewicz, Artur, Metze, Dieter, Hillen, Uwe, Richter, Julia, Spang, Rainer, Klapper, Wolfram
Published in Journal of investigative dermatology (01.11.2017)

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Epidermal growth factor receptor (EGFR) in salivary gland carcinomas: Potentials as therapeutic target

Epidermal growth factor receptor (EGFR) in salivary gland carcinomas: Potentials as therapeutic target

by Clauditz, Till Sebastian, Gontarewicz, Artur, Lebok, Patrick, Tsourlakis, Maria-Christina, Grob, Tobias J, Münscher, Adrian, Sauter, Guido, Bokemeyer, Carsten, Knecht, Rainald, Wilczak, Waldemar
Published in Oral oncology (01.10.2012)

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Targeting Aurora Kinases with Danusertib (PHA-739358) Inhibits Growth of Liver Metastases from Gastroenteropancreatic Neuroendocrine Tumors in an Orthotopic Xenograft Model

Targeting Aurora Kinases with Danusertib (PHA-739358) Inhibits Growth of Liver Metastases from Gastroenteropancreatic Neuroendocrine Tumors in an Orthotopic Xenograft Model

by FRAEDRICH, Katharina, SCHRADER, Jörg, LOSE, Ansgar W, HÖRSCH, Dieter, BRÜMMENDORF, Tim H, BENTEN, Daniel, ITTRICH, Harald, KELLER, Gunhild, GONTAREWICZ, Artur, MATZAT, Verena, KROMMINGA, Arno, PACE, Andrea, MOLL, Jürgen, BLÄKER, Michael
Published in Clinical cancer research (01.09.2012)

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Abundant expression of m TOR kinase in salivary gland tumors – potentials as therapy target?

Abundant expression of m TOR kinase in salivary gland tumors – potentials as therapy target?

by Clauditz, Till Sebastian, Gontarewicz, Artur, Bokemeyer, Carsten, Sauter, Guido, Knecht, Rainald, Münscher, Adrian, Wilczak, Waldemar
Published in Journal of oral pathology & medicine (01.11.2013)

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Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL–positive CML cells

Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL–positive CML cells

by Brassat, Ute, Balabanov, Stefan, Bali, Daniel, Dierlamm, Judith, Braig, Melanie, Hartmann, Ulrike, Sirma, Hüseyin, Günes, Cagatay, Wege, Henning, Fehse, Boris, Gontarewicz, Artur, Dikomey, Ekkehard, Borgmann, Kerstin, Brümmendorf, Tim H
Published in Experimental hematology (2011)

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11q21 rearrangement is a frequent and highly specific genetic alteration in mucoepidermoid carcinoma

11q21 rearrangement is a frequent and highly specific genetic alteration in mucoepidermoid carcinoma

by Clauditz, Till Sebastian, Gontarewicz, Artur, Wang, Chia-Jung, Münscher, Adrian, Laban, Simon, Tsourlakis, Maria Christina, Knecht, Rainald, Sauter, Guido, Wilczak, Waldemar
Published in Diagnostic molecular pathology (01.09.2012)

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Analysis of the tumor microenvironment by whole-slide image analysis identifies low B cell content as a predictor of adverse outcome in advanced-stage classical Hodgkin lymphoma treated with BEACOPP

Analysis of the tumor microenvironment by whole-slide image analysis identifies low B cell content as a predictor of adverse outcome in advanced-stage classical Hodgkin lymphoma treated with BEACOPP

by Jachimowicz, Ron Daniel, Pieper, Luise, Reinke, Sarah, Gontarewicz, Artur, Plütschow, Annette, Haverkamp, Heinz, Frauenfeld, Leonie, Fend, Falko, Overkamp, Mathis, Jochims, Franziska, Thorns, Christoph, Hansmann, Martin Leo, Möller, Peter, Rosenwald, Andreas, Stein, Harald, Reinhardt, Hans Christian, Borchmann, Peter, von Tresckow, Bastian, Engert, Andreas, Klapper, Wolfram
Published in Haematologica (Roma) (07.05.2020)

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Resistance to Danusertib (formerly PHA-739358) in BCR-ABL-Positive Cells Is Mediated by Upregulation of the Drug Transporter Abcg2 and Can Be Suppressed in Vitro by Combination Treatment with Imatinib

Resistance to Danusertib (formerly PHA-739358) in BCR-ABL-Positive Cells Is Mediated by Upregulation of the Drug Transporter Abcg2 and Can Be Suppressed in Vitro by Combination Treatment with Imatinib

by Brummendorf, Tim H, Gontarewicz, Artur, Keller, Gunhild, Moll, Jürgen, Braig, Melanie, Rohe, Imke, Jost, Edgar, Galm, Oliver, Bokemeyer, Carsten, Holyoake, Tessa, Balabanov, Stefan
Published in Blood (20.11.2009)

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Combination Therapy of Small Molecule Inhibitor PHA-739358 and Tyrosine Kinase Inhibitor Imatinib Yields Synergistic Antiproliferative Effects and Suppresses Emergence of Resistance of Chronic Myeloid Leukemia in Vitro

Combination Therapy of Small Molecule Inhibitor PHA-739358 and Tyrosine Kinase Inhibitor Imatinib Yields Synergistic Antiproliferative Effects and Suppresses Emergence of Resistance of Chronic Myeloid Leukemia in Vitro

by Balabanov, Stefan, Gontarewicz, Artur, Keller, Gunhild, Moll, Jürgen, Bokemeyer, Carsten, Holyoake, Tessa L, Brummendorf, Tim H.
Published in Blood (16.11.2008)

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Identification of Novel Biomarkers for Prediction of Response to Tyrosine Kinase Inhibitors (TKIs) by Proteomic Profiling of Imatinib as Well as 2nd and 3rd Generation TKIs in Vitro

Identification of Novel Biomarkers for Prediction of Response to Tyrosine Kinase Inhibitors (TKIs) by Proteomic Profiling of Imatinib as Well as 2nd and 3rd Generation TKIs in Vitro

by Balabanov, Stefan, Wilhelm, Thoma, Venz, Simone, Barret, Christine, Keller, Gunhild, Bernhardt, Mirja, Gontarewicz, Artur, Braig, Melanie, Walther, Reinhard, Brummendorf, Tim H.
Published in Blood (16.11.2008)

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