Identification of natural product modulators of Merkel cell carcinoma cell growth and survival
Smith, Emily A, Hill, Natasha T, Gelb, Tara, Garman, Khalid A, Goncharova, Ekaterina I, Bokesch, Heidi R, Kim, Chang-Kwon, Wendt, Karen L, Cichewicz, Robert H, Gustafson, Kirk R, Brownell, Isaac, Henrich, Curtis J
Published in Scientific reports (30.06.2021)
Published in Scientific reports (30.06.2021)
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Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana
Jiang, Wei, Wang, Dongdong, Wilson, Brice A P, Kang, Unwoo, Bokesch, Heidi R, Smith, Emily A, Wamiru, Antony, Goncharova, Ekaterina I, Voeller, Donna, Lipkowitz, Stanley, O'Keefe, Barry R, Gustafson, Kirk R
Published in Marine drugs (24.06.2021)
Published in Marine drugs (24.06.2021)
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A Molecular Networking Strategy: High-Throughput Screening and Chemical Analysis of Brazilian Cerrado Plant Extracts against Cancer Cells
Cortelo, Patrícia C, Demarque, Daniel P, Dusi, Renata G, Albernaz, Lorena C, Braz-Filho, Raimundo, Goncharova, Ekaterina I, Bokesch, Heidi R, Gustafson, Kirk R, Beutler, John A, Espindola, Laila S
Published in Cells (Basel, Switzerland) (20.03.2021)
Published in Cells (Basel, Switzerland) (20.03.2021)
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Journal Article
A high-throughput cell-based assay for inhibitors of ABCG2 activity
Henrich, Curtis J, Bokesch, Heidi R, Dean, Michael, Bates, Susan E, Robey, Robert W, Goncharova, Ekaterina I, Wilson, Jennifer A, McMahon, James B
Published in Journal of biomolecular screening (01.03.2006)
Published in Journal of biomolecular screening (01.03.2006)
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Journal Article
cell-based high-throughput screen to identify synergistic TRAIL sensitizers
Booth, Nancy Lynn, Sayers, Thomas J, Brooks, Alan D, Thomas, Cheryl L, Jacobsen, Kristen, Goncharova, Ekaterina I, McMahon, James B, Henrich, Curtis J
Published in Cancer Immunology, Immunotherapy (01.08.2009)
Published in Cancer Immunology, Immunotherapy (01.08.2009)
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Journal Article
Photochemical Dimerization of Plakinidine B Leads to Potent Inhibition of the E3 Ubiquitin-Protein Ligase CBL‑B
Khong, Quan T., Li, Donghao, Wilson, Brice A. P., Ranguelova, Kalina, Dalilian, Masoumeh, Smith, Emily A., Wamiru, Antony, Goncharova, Ekaterina I., Grkovic, Tanja, Voeller, Donna, Lipkowitz, Stanley, Schnermann, Martin J., O’Keefe, Barry R., Du, Lin
Published in Organic letters (30.12.2022)
Published in Organic letters (30.12.2022)
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The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation
Matarlo, Joe S, Krumpe, Lauren R H, Heinz, William F, Oh, Daniel, Shenoy, Shilpa R, Thomas, Cheryl L, Goncharova, Ekaterina I, Lockett, Stephen J, O'Keefe, Barry R
Published in Cell chemical biology (15.08.2019)
Published in Cell chemical biology (15.08.2019)
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Journal Article
Chemoreactive 2,5-Diketopiperazines from a Penicillium sp., Structure Revision of Reported Analogues and Proposed Facile Transformation Pathways
Khong, Quan T., Smith, Emily A., Wendt, Karen L., Dalilian, Masoumeh, Goncharova, Ekaterina I., Brownell, Isaac, Cichewicz, Robert H., Henrich, Curtis J., Beutler, John A., O’Keefe, Barry R., Du, Lin
Published in Journal of natural products (Washington, D.C.) (26.07.2024)
Published in Journal of natural products (Washington, D.C.) (26.07.2024)
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Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases
Du, Lin, Wilson, Brice A. P., Li, Ning, Shah, Rohan, Dalilian, Masoumeh, Wang, Dongdong, Smith, Emily A., Wamiru, Antony, Goncharova, Ekaterina I., Zhang, Ping, O’Keefe, Barry R.
Published in Journal of natural products (Washington, D.C.) (27.10.2023)
Published in Journal of natural products (Washington, D.C.) (27.10.2023)
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Journal Article
Development of a High-throughput NanoBRET Screening Platform to Identify Modulators of the RAS/RAF Interaction
Durrant, David E, Smith, Emily A, Goncharova, Ekaterina I, Sharma, Nirmala, Alexander, Patrick A, Stephen, Andrew G, Henrich, Curtis J, Morrison, Deborah K
Published in Molecular cancer therapeutics (01.09.2021)
Published in Molecular cancer therapeutics (01.09.2021)
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Journal Article
Identification of potential modulators of osteosarcoma metastasis by high‐throughput cellular screening of natural products
Long, Sarah A., Huang, Shan, Kambala, Anusha, Ren, Ling, Wilson, Jennifer, Goetz, Michael, Hao, Xiaojiang, Yang, Xiaosheng, Goncharova, Ekaterina I., Jia, Libin, LeBlanc, Amy, Khanna, Chand, Henrich, Curtis J., Beutler, John A.
Published in Chemical biology & drug design (01.01.2021)
Published in Chemical biology & drug design (01.01.2021)
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Journal Article
Natural Products Active in Aberrant c-Kit Signaling
Henrich, Curtis J., Goncharova, Ekaterina I., Wilson, Jennifer A., Gardella, Roberta S., Johnson, Tanya R., McMahon, James B., Takada, Kentaro, Bokesch, Heidi R., Gustafson, Kirk R.
Published in Chemical biology & drug design (01.05.2007)
Published in Chemical biology & drug design (01.05.2007)
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Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3′,5′-Cyclic Monophosphate-Dependent Protein Kinase A (PKA) Inhibitors
Wilson, Brice A. P., Li, Ning, Martinez Fiesco, Juliana A., Dalilian, Masoumeh, Wang, Dongdong, Smith, Emily A., Wamiru, Antony, Shah, Rohan, Goncharova, Ekaterina I., Beutler, John A., Grkovic, Tanja, Zhang, Ping, O’Keefe, Barry R.
Published in ACS pharmacology & translational science (14.04.2023)
Published in ACS pharmacology & translational science (14.04.2023)
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Journal Article
In Vitro Ubiquitination Platform Identifies Methyl Ellipticiniums as Ubiquitin Ligase Inhibitors
Wilson, Brice A.P., Voeller, Donna, Smith, Emily A., Wamiru, Antony, Goncharova, Ekaterina I., Liu, Gang, Lipkowitz, Stanley, O’Keefe, Barry R.
Published in SLAS discovery (01.08.2021)
Published in SLAS discovery (01.08.2021)
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Journal Article
Discovery and Characterization of a Biologically Active Non-ATP-Competitive p38 MAP Kinase Inhibitor
Wilson, Brice A P, Alam, Muhammad S, Guszczynski, Tad, Jakob, Michal, Shenoy, Shilpa R, Mitchell, Carter A, Goncharova, Ekaterina I, Evans, Jason R, Wipf, Peter, Liu, Gang, Ashwell, Jonathan D, O'Keefe, Barry R
Published in Journal of biomolecular screening (01.03.2016)
Published in Journal of biomolecular screening (01.03.2016)
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Journal Article
Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1)
Bermingham, Alun, Price, Edmund, Marchand, Christophe, Chergui, Adel, Naumova, Alena, Whitson, Emily L., Krumpe, Lauren R. H., Goncharova, Ekaterina I., Evans, Jason R., McKee, Tawnya C., Henrich, Curtis J., Pommier, Yves, O’Keefe, Barry R.
Published in SLAS discovery (01.10.2017)
Published in SLAS discovery (01.10.2017)
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Journal Article
High-throughput Screening for Identification of Inhibitors of EpCAM-Dependent Growth of Hepatocellular Carcinoma Cells
Henrich, Curtis J., Budhu, Anuradha, Yu, Zhipeng, Evans, Jason R., Goncharova, Ekaterina I., Ransom, Tanya T., Wang, Xin W., McMahon, James B.
Published in Chemical biology & drug design (01.08.2013)
Published in Chemical biology & drug design (01.08.2013)
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Journal Article
Identification of compounds by high-content screening that induce cytoplasmic to nuclear localization of a fluorescent estrogen receptor α chimera and exhibit agonist or antagonist activity in vitro
Dull, Angie B, George, Anuja A, Goncharova, Ekaterina I, Evans, Jason R, Wamiru, Antony, Cartner, Laura K, Hager, Gordon L, McMahon, James B
Published in Journal of biomolecular screening (01.02.2014)
Published in Journal of biomolecular screening (01.02.2014)
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Journal Article
Development of a High-Throughput Cell-Based Reporter Assay to Identify Stabilizers of Tumor Suppressor Pdcd4
Blees, Johanna S., Schmid, Tobias, Thomas, Cheryl L., Baker, Alyson R., Benson, Lauren, Evans, Jason R., Goncharova, Ekaterina I., Colburn, Nancy H., McMahon, James B., Henrich, Curtis J.
Published in Journal of biomolecular screening (01.01.2010)
Published in Journal of biomolecular screening (01.01.2010)
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