Mammalian Target of Rapamycin Complex 2 (mTORC2) Coordinates Pulmonary Artery Smooth Muscle Cell Metabolism, Proliferation, and Survival in Pulmonary Arterial Hypertension
Goncharov, Dmitry A, Kudryashova, Tatiana V, Ziai, Houman, Ihida-Stansbury, Kaori, DeLisser, Horace, Krymskaya, Vera P, Tuder, Rubin M, Kawut, Steven M, Goncharova, Elena A
Published in Circulation (New York, N.Y.) (25.02.2014)
Published in Circulation (New York, N.Y.) (25.02.2014)
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Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival
Kudryashova, Tatiana V, Dabral, Swati, Nayakanti, Sreenath, Ray, Arnab, Goncharov, Dmitry A, Avolio, Theodore, Shen, Yuanjun, Rode, Analise, Pena, Andressa, Jiang, Lifeng, Lin, Derek, Baust, Jeffrey, Bachman, Timothy N, Graumann, Johannes, Ruppert, Clemens, Guenther, Andreas, Schmoranzer, Mario, Grobs, Yann, Eve Lemay, Sarah, Tremblay, Eve, Breuils-Bonnet, Sandra, Boucherat, Olivier, Mora, Ana L, DeLisser, Horace, Zhao, Jing, Zhao, Yutong, Bonnet, Sébastien, Seeger, Werner, Pullamsetti, Soni S, Goncharova, Elena A
Published in Circulation research (04.03.2022)
Published in Circulation research (04.03.2022)
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Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation
Ghouleh, Imad Al, Sahoo, Sanghamitra, Meijles, Daniel N, Amaral, Jefferson H, de Jesus, Daniel S, Sembrat, John, Rojas, Mauricio, Goncharov, Dmitry A, Goncharova, Elena A, Pagano, Patrick J
Published in Clinical science (1979) (01.08.2017)
Published in Clinical science (1979) (01.08.2017)
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mTORC2 Is Required for Proliferation and Survival of TSC2-Null Cells
Goncharova, Elena A., Goncharov, Dmitry A., Li, Hua, Pimtong, Wittaya, Lu, Stephen, Khavin, Irene, Krymskaya, Vera P.
Published in Molecular and Cellular Biology (01.06.2011)
Published in Molecular and Cellular Biology (01.06.2011)
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Folliculin Controls Lung Alveolar Enlargement and Epithelial Cell Survival through E-Cadherin, LKB1, and AMPK
Goncharova, Elena A., Goncharov, Dmitry A., James, Melane L., Atochina-Vasserman, Elena N., Stepanova, Victoria, Hong, Seung-Beom, Li, Hua, Gonzales, Linda, Baba, Masaya, Linehan, W. Marston, Gow, Andrew J., Margulies, Susan, Guttentag, Susan, Schmidt, Laura S., Krymskaya, Vera P.
Published in Cell reports (Cambridge) (24.04.2014)
Published in Cell reports (Cambridge) (24.04.2014)
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mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia
Krymskaya, Vera P, Snow, Jennifer, Cesarone, Gregory, Khavin, Irene, Goncharov, Dmitry A, Lim, Poay N, Veasey, Sigrid C, Ihida-Stansbury, Kaori, Jones, Peter L, Goncharova, Elena A
Published in The FASEB journal (01.06.2011)
Published in The FASEB journal (01.06.2011)
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Functional NMDA receptors are expressed by human pulmonary artery smooth muscle cells
Dong, Yi Na, Hsu, Fu-Chun, Koziol-White, Cynthia J., Stepanova, Victoria, Jude, Joseph, Gritsiuta, Andrei, Rue, Ryan, Mott, Rosalind, Coulter, Douglas A., Panettieri, Reynold A., Krymskaya, Vera P., Takano, Hajime, Goncharova, Elena A., Goncharov, Dmitry A., Cines, Douglas B., Lynch, David R.
Published in Scientific reports (15.04.2021)
Published in Scientific reports (15.04.2021)
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Inhibitory Antibodies against Activin A and TGF-β Reduce Self-Supported, but Not Soluble Factors-Induced Growth of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension
Kudryashova, Tatiana V, Shen, Yuanjun, Pena, Andressa, Cronin, Emily, Okorie, Evelyn, Goncharov, Dmitry A, Goncharova, Elena A
Published in International journal of molecular sciences (28.09.2018)
Published in International journal of molecular sciences (28.09.2018)
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Akt-Dependent Glycolysis-Driven Lipogenesis Supports Proliferation and Survival of Human Pulmonary Arterial Smooth Muscle Cells in Pulmonary Hypertension
Jiang, Lifeng, Goncharov, Dmitry A., Shen, Yuanjun, Lin, Derek, Chang, Baojun, Pena, Andressa, DeLisser, Horace, Goncharova, Elena A., Kudryashova, Tatiana V.
Published in Frontiers in medicine (28.06.2022)
Published in Frontiers in medicine (28.06.2022)
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Signal Transducer and Activator of Transcription 3 Is Required for Abnormal Proliferation and Survival of TSC2-Deficient Cells: Relevance to Pulmonary Lymphangioleiomyomatosis
Goncharova, Elena A, Goncharov, Dmitry A, Damera, Gautam, Tliba, Omar, Amrani, Yassine, Panettieri, Jr, Reynold A, Krymskaya, Vera P
Published in Molecular pharmacology (01.10.2009)
Published in Molecular pharmacology (01.10.2009)
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Differential effects of integrin-linked kinase inhibitor Cpd22 on severe pulmonary hypertension in male and female rats
Shen, Yuanjun, Goncharov, Dmitry A., Avolio, Theodore, Ray, Arnab, Okorie, Evelyn, DeLisser, Horace, Mora, Ana L., Vanderpool, Rebecca, Kudryashova, Tatiana V., Goncharova, Elena A.
Published in Pulmonary circulation (01.01.2020)
Published in Pulmonary circulation (01.01.2020)
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Distinct plasma gradients of microRNA-204 in the pulmonary circulation of patients suffering from WHO Groups I and II pulmonary hypertension
Estephan, Leonard E., Genuardi, Michael V., Kosanovich, Chad M., Risbano, Michael G., Zhang, Yingze, Petro, Nancy, Watson, Annie, Al Aaraj, Yassmin, Sembrat, John C., Rojas, Mauricio, Goncharov, Dmitry A., Simon, Marc A., Goncharova, Elena A., Vaidya, Anjali, Smith, Akaya, Mazurek, Jeremy, Han, Yuchi, Chan, Stephen Y.
Published in Pulmonary circulation (01.04.2019)
Published in Pulmonary circulation (01.04.2019)
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SIRT3-AMP-Activated Protein Kinase Activation by Nitrite and Metformin Improves Hyperglycemia and Normalizes Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction
Lai, Yen-Chun, Tabima, Diana M, Dube, John J, Hughan, Kara S, Vanderpool, Rebecca R, Goncharov, Dmitry A, St Croix, Claudette M, Garcia-Ocaña, Adolfo, Goncharova, Elena A, Tofovic, Stevan P, Mora, Ana L, Gladwin, Mark T
Published in Circulation (New York, N.Y.) (23.02.2016)
Published in Circulation (New York, N.Y.) (23.02.2016)
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Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration
Krymskaya, Vera P, Goncharova, Elena A, Ammit, Alaina J, Lim, Poay N, Goncharov, Dmitry A, Eszterhas, Andrew, Panettieri, Reynold A
Published in The FASEB journal (01.03.2005)
Published in The FASEB journal (01.03.2005)
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Metabolic Syndrome Mediates ROS-miR-193b-NFYA-Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction
Satoh, Taijyu, Wang, Longfei, Espinosa-Diez, Cristina, Wang, Bing, Hahn, Scott A, Noda, Kentaro, Rochon, Elizabeth R, Dent, Matthew R, Levine, Andrea R, Baust, Jeffrey J, Wyman, Samuel, Wu, Yijen L, Triantafyllou, Georgios A, Tang, Ying, Reynolds, Mike, Shiva, Sruti, Hilaire, Cynthia St, Gomez, Delphine, Goncharov, Dmitry A, Goncharova, Elena A, Chan, Stephen Y, Straub, Adam C, Lai, Yen-Chun, McTiernan, Charles F, Gladwin, Mark T
Published in Circulation (New York, N.Y.) (24.08.2021)
Published in Circulation (New York, N.Y.) (24.08.2021)
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HIPPO-Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension
Kudryashova, Tatiana V, Goncharov, Dmitry A, Pena, Andressa, Kelly, Neil, Vanderpool, Rebecca, Baust, Jeff, Kobir, Ahasanul, Shufesky, William, Mora, Ana L, Morelli, Adrian E, Zhao, Jing, Ihida-Stansbury, Kaori, Chang, Baojun, DeLisser, Horace, Tuder, Rubin M, Kawut, Steven M, Silljé, Herman H W, Shapiro, Steven, Zhao, Yutong, Goncharova, Elena A
Published in American journal of respiratory and critical care medicine (01.10.2016)
Published in American journal of respiratory and critical care medicine (01.10.2016)
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Mitochondria as a primary determinant of angiogenic modality in pulmonary arterial hypertension
Niihori, Maki, James, Joel, Varghese, Mathews V, McClain, Nolan, Lawal, Odunayo Susan, Philip, Rohit C, Baggett, Brenda K, Goncharov, Dmitry A, de Jesus Perez, Vinicio, Goncharova, Elena A, Rafikov, Ruslan, Rafikova, Olga
Published in The Journal of experimental medicine (04.11.2024)
Published in The Journal of experimental medicine (04.11.2024)
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Skeletal Muscle SIRT3 Deficiency Contributes to Pulmonary Vascular Remodeling in Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction
Jheng, Jia-Rong, Bai, Yang, Noda, Kentaro, Huot, Joshua R, Cook, Todd, Fisher, Amanda, Chen, Yi-Yun, Goncharov, Dmitry A, Goncharova, Elena A, Simon, Marc A, Zhang, Yingze, Forman, Daniel E, Rojas, Mauricio, Machado, Roberto F, Auwerx, Johan, Gladwin, Mark T, Lai, Yen-Chun
Published in Circulation (New York, N.Y.) (10.09.2024)
Published in Circulation (New York, N.Y.) (10.09.2024)
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