Discovery of (R)‑1-(7-Chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea (A-1165442): A Temperature-Neutral Transient Receptor Potential Vanilloid‑1 (TRPV1) Antagonist with Analgesic Efficacy
Voight, Eric A, Gomtsyan, Arthur R, Daanen, Jerome F, Perner, Richard J, Schmidt, Robert G, Bayburt, Erol K, DiDomenico, Stanley, McDonald, Heath A, Puttfarcken, Pamela S, Chen, Jun, Neelands, Torben R, Bianchi, Bruce R, Han, Ping, Reilly, Regina M, Franklin, Pamela H, Segreti, Jason A, Nelson, Richard A, Su, Zhi, King, Andrew J, Polakowski, James S, Baker, Scott J, Gauvin, Donna M, Lewis, LaGeisha R, Mikusa, Joseph P, Joshi, Shailen K, Faltynek, Connie R, Kym, Philip R, Kort, Michael E
Published in Journal of medicinal chemistry (11.09.2014)
Published in Journal of medicinal chemistry (11.09.2014)
Get full text
Journal Article
CHROMANYLUREA COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1(VR1) RECEPTOR AND USES THEREOF
SCHMIDT ROBERT G. JR, BROWN S. BRIAN, GOMTSYAN ARTHUR R, KOENIG R. JOHN, BAYBURT EROL K, DAANEN F. JEROME, LATSHAW STEVE, LEE CHIH HUNG, JINKERSON K. TAMMIE
Year of Publication 20.12.2012
Get full text
Year of Publication 20.12.2012
Patent
Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
BAYBURT EROL K.,DIDOMENICO STANLEY JR.,DRIZIN IRENE,GOMTSYAN ARTHUR R.,KOENIG JOHN R.,PENNER RICHARD J.,SCHMIDT ROBERT G. JR.,TURNER SEAN C.,WHITE TAMMIE K.,ZHENG GUO ZHU
Year of Publication 15.11.2006
Get full text
Year of Publication 15.11.2006
Patent
TRPV3 MODULATORS
Frost, Jennifer, Shrestha, Anurupa, Cowart, Marlon D, Shi, Lei, Sippy, Kevin, Black, Lawrence, Faghih, Ramin, Schmidt, Robert G, Brown, Brian S, Clapham, Bruce, Liu, Huaqing, Gomtsyan, Arthur R, Kym, Philip R, Dart, Michael J
Year of Publication 30.08.2018
Get full text
Year of Publication 30.08.2018
Patent
N-(1,3-THIAZOL-2-YL)PYRIMIDINE-5-CARBOXAMIDES AS TRPV3 MODULATORS
SHI, Lei, SIPPY, Kevin, KYM, Philip R, CLAPHAM, Bruce, FAGHIH, Ramin, SCHMIDT, Robert G, FROST, Jennifer, COWART, Marlon D, SHRESTHA, Anurupa, LIU, Huaqing, BROWN, Brian S, DART, Michael J, BLACK, Lawrence, GOMTSYAN, Arthur R
Year of Publication 06.10.2016
Get full text
Year of Publication 06.10.2016
Patent
TRPV1 antagonists
KORT MICHAEL E, GOMTSYAN ARTHUR R, BAYBURT EROL K, SCHMIDT ROBERT G, DAANEN JEROME F
Year of Publication 25.12.2012
Get full text
Year of Publication 25.12.2012
Patent
TRPV1 antagonists
Gomtsyan, Arthur R, Schmidt, Robert G, Bayburt, Erol K, Daanen, Jerome F, Kort, Michael E
Year of Publication 25.12.2012
Get full text
Year of Publication 25.12.2012
Patent
TRPV1 ANTAGONISTS
KORT MICHAEL E, GOMTSYAN ARTHUR R, BAYBURT EROL K, SCHMIDT ROBERT G, DAANEN JEROME F
Year of Publication 03.05.2012
Get full text
Year of Publication 03.05.2012
Patent
TRPV1 antagonists
Gomtsyan, Arthur R, Schmidt, Robert G, Bayburt, Erol K, Daanen, Jerome F, Kort, Michael E
Year of Publication 27.12.2011
Get full text
Year of Publication 27.12.2011
Patent
TRPV1 antagonists
KORT MICHAEL E, GOMTSYAN ARTHUR R, BAYBURT EROL K, SCHMIDT ROBERT G, DAANEN JEROME F
Year of Publication 27.12.2011
Get full text
Year of Publication 27.12.2011
Patent
Indazole derivatives that inhibit TRPV1 receptor
MARSH, KENNAN C, GOMTSYAN, ARTHUR R, KOENIG, JOHN R, SCHMIDT, ROBERT G, LEE, BAYBURT, EROL K
Year of Publication 28.10.2011
Get full text
Year of Publication 28.10.2011
Patent
Antagonists of the TRPV1 receptor and uses thereof
Gomtsyan, Arthur R, Schmidt, Robert G, Daanen, Jerome F, Bayburt, Erol K, Lee, Chih-hung, Latshaw, Steven P
Year of Publication 08.01.2013
Get full text
Year of Publication 08.01.2013
Patent
Antagonists of the TRPV1 receptor and uses thereof
GOMTSYAN ARTHUR R, BAYBURT EROL K, LEE CHIH-HUNG, SCHMIDT ROBERT G, LATSHAW STEVEN P, DAANEN JEROME F
Year of Publication 08.01.2013
Get full text
Year of Publication 08.01.2013
Patent
ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1(VR1) AND USES THEREOF
GOMTSYAN ARTHUR R, PERNER RICHARD J, KOENIG JOHN R, LEE CHIH-HUNG, HSU MARGARET CHI-PING, FERNANDO DILNIE P
Year of Publication 27.12.2012
Get full text
Year of Publication 27.12.2012
Patent