A Naphthyridine Carboxamide Provides Evidence for Discordant Resistance between Mechanistically Identical Inhibitors of HIV-1 Integrase
Hazuda, Daria J., Anthony, Neville J., Gomez, Robert P., Jolly, Samson M., Wai, John S., Zhuang, Linghang, Fisher, Thorsten E., Embrey, Mark, Guare, James P., Egbertson, Melissa S., Vacca, Joseph P., Huff, Joel R., Felock, Peter J., Witmer, Marc V., Stillmock, Kara A., Danovich, Robert, Grobler, Jay, Miller, Michael D., Espeseth, Amy S., Jin, Lixia, I-Wu Chen, Lin, Jiunn H., Kassahun, Kelem, Ellis, Joan D., Wong, Bradley K., Xu, Wei, Pearson, Paul G., Schleif, William A., Cortese, Riccardo, Emini, Emilio, Summa, Vincenzo, Holloway, M. Katharine, Young, Steven D., Coffin, John M.
Published in Proceedings of the National Academy of Sciences - PNAS (03.08.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (03.08.2004)
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Integrase Inhibitors and Cellular Immunity Suppress Retroviral Replication in Rhesus Macaques
Hazuda, Daria J., Young, Steven D., Guare, James P., Anthony, Neville J., Gomez, Robert P., Wai, John S., Vacca, Joseph P., Handt, Larry, Motzel, Sherri L., Klein, Hilton J., Dornadula, Geethanjali, Danovich, Robert M., Witmer, Marc V., Keith A. A. Wilson, Tussey, Lynda, Schleif, William A., Gabryelski, Lori S., Jin, Lixia, Miller, Michael D., Casimiro, Danilo R., Emini, Emilio A., Shiver, John W.
Published in Science (American Association for the Advancement of Science) (23.07.2004)
Published in Science (American Association for the Advancement of Science) (23.07.2004)
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Design and in Vivo Analysis of Potent Non-Thiol Inhibitors of Farnesyl Protein Transferase
Anthony, Neville J, Gomez, Robert P, Schaber, Micheal D, Mosser, Scott D, Hamilton, Kelly A, O'Neil, Timothy J, Koblan, Kenneth S, Graham, Samuel L, Hartman, George D, Shah, Daksha, Rands, Elaine, Kohl, Nancy E, Gibbs, Jackson B, Oliff, Allen I
Published in Journal of medicinal chemistry (26.08.1999)
Published in Journal of medicinal chemistry (26.08.1999)
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Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice
Kohl, N E, Omer, C A, Conner, M W, Anthony, N J, Davide, J P, deSolms, S J, Giuliani, E A, Gomez, R P, Graham, S L, Hamilton, K
Published in Nature medicine (01.08.1995)
Published in Nature medicine (01.08.1995)
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Journal Article
A series of 5-aminosubstituted 4-fluorobenzyl-8-hydroxy-[1,6]naphthyridine-7-carboxamide HIV-1 integrase inhibitors
Guare, James P., Wai, John S., Gomez, Robert P., Anthony, Neville J., Jolly, Samson M., Cortes, Amanda R., Vacca, Joseph P., Felock, Peter J., Stillmock, Kara A., Schleif, William A., Moyer, Gregory, Gabryelski, Lori J., Jin, Lixia, Chen, I-Wu, Hazuda, Daria J., Young, Steven D.
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
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Journal Article
Rational design of 4-[(methylsulfonyl)amino]benzamides as class III antiarrhythmic agents
Lumma, William C, Wohl, Ronald A, Davey, David D, Argentieri, Thomas M, DeVita, Robert J, Gomez, Robert P, Jain, Vijay K, Marisca, Anthony J, Morgan, Thomas K
Published in Journal of medicinal chemistry (01.05.1987)
Published in Journal of medicinal chemistry (01.05.1987)
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Journal Article
Synthesis and cardiac electrophysiological activity of N-substituted-4-(1H-imidazol-1-yl)benzamides - new selective class III agents
Morgan, Thomas K, Lis, Randall, Lumma, William C, Nickisch, Klaus, Wohl, Ronald A, Phillips, Gary B, Gomez, Robert P, Lampe, John W, Di Meo, Susan V
Published in Journal of medicinal chemistry (01.04.1990)
Published in Journal of medicinal chemistry (01.04.1990)
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Journal Article
Synthesis, cardiac electrophysiology, and .beta.-blocking activity of novel arylpiperazines with potential as class II/III antiarrhythmic agents
Phillips, Gary B, Morgan, Thomas K, Lumma, William C, Gomez, Robert P, Lind, Joan M, Lis, Randall, Argentieri, Thomas, Sullivan, Mark E
Published in Journal of medicinal chemistry (01.02.1992)
Published in Journal of medicinal chemistry (01.02.1992)
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Cardiotonic agents. 5. Fragments from the heterocycle-phenyl-imidazole pharmacophore
Erhardt, Paul W, Hagedorn, Alfred A, Davey, David, Pease, Cynthia A, Venepalli, Bhaskar R, Griffin, Carl W, Gomez, Robert P, Wiggins, Jay R, Ingebretsen, William R
Published in Journal of medicinal chemistry (01.06.1989)
Published in Journal of medicinal chemistry (01.06.1989)
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Journal Article
Synthesis of novel (aryloxy)propanolamines and related compounds possessing both class II and class III antiarrhythmic activity
Lis, Randall, Morgan, Thomas K, Marisca, Anthony J, Gomez, Robert P, Lind, Joan M, Davey, David D, Phillips, Gary B, Sullivan, Mark E
Published in Journal of medicinal chemistry (01.10.1990)
Published in Journal of medicinal chemistry (01.10.1990)
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Synthesis and cardiac electrophysiological activity of aryl-substituted derivatives of the class III antiarrhythmic agent sematilide. Potential class I/III agents
Phillips, Gary B, Morgan, Thomas K, Nickisch, Klaus, Lind, Joan M, Gomez, Robert P, Wohl, Ronald A, Argentieri, Thomas M, Sullivan, Mark E
Published in Journal of medicinal chemistry (01.02.1990)
Published in Journal of medicinal chemistry (01.02.1990)
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Protein Farnesyltransferase Inhibitors Block the Growth of ras-Dependent Tumors in Nude Mice
Kohl, Nancy E., Wilson, Francine R., Mosser, Scott D., Giuliani, Elizabeth, deSolms, S. Jane, Conner, Michael W., Anthony, Neville J., Holtz, Wilbur J., Gomez, Robert P., Lee, Ta-Jyh, Smith, Robert L., Graham, Samuel L., Hartman, George D., Gibbs, Jackson B., Oliff, Allen
Published in Proceedings of the National Academy of Sciences - PNAS (13.09.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (13.09.1994)
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Synthesis and Class III antiarrhythmic activity of (phenyl-2-butenyl)ammonium salts. Effect of conformation on activity
Morgan, Thomas K, Wohl, Ronald A, Lumma, William C, Wan, Chung Nan, Davey, David D, Gomez, Robert P, Marisca, Anthony J, Briggs, Martha, Sullivan, Mark E, Wong, Samuel S
Published in Journal of medicinal chemistry (01.08.1986)
Published in Journal of medicinal chemistry (01.08.1986)
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TRICYCLIC MGLUR5 RECEPTOR MODULATORS
MERCER, SWATI, P, ANTHONY, NEVILLE, J, GOMEZ, ROBERT, P, STUMP, CRAIG, A, WILLIAMS, THERESA, M, ROECKER, ANTHONY, J, LI, JING
Year of Publication 10.04.2014
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Year of Publication 10.04.2014
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TRICYCLIC MGLUR5 RECEPTOR MODULATORS
MERCER, SWATI, P, ANTHONY, NEVILLE, J, ROECKER, ANTONY, J, GOMEZ, ROBERT, P, STUMP, CRAIG, A, WILLIAMS, THERESA, M, LI, JING
Year of Publication 04.09.2013
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Year of Publication 04.09.2013
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TRICYCLIC MGLUR5 RECEPTOR MODULATORS
ROECKER ANTHONY J, MERCER SWATI P, WILLIAMS THERESA M, ANTHONY NEVILLE J, LI JING, GOMEZ ROBERT P, STUMP CRAIG A
Year of Publication 15.08.2013
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Year of Publication 15.08.2013
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TRICYCLIC MGLUR5 RECEPTOR MODULATORS
MERCER, SWATI, P, ANTHONY, NEVILLE, J, GOMEZ, ROBERT, P, STUMP, CRAIG, A, WILLIAMS, THERESA, M, ROECKER, ANTHONY, J, LI, JING
Year of Publication 10.05.2012
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Year of Publication 10.05.2012
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