Gene Set Enrichment Analysis: A Knowledge-Based Approach for Interpreting Genome-Wide Expression Profiles
Subramanian, Aravind, Tamayo, Pablo, Mootha, Vamsi K., Mukherjee, Sayan, Benjamin L. Ebert, Michael A. Gillette, Amanda Paulovich, Pomeroy, Scott L., Golub, Todd R., Lander, Eric S., Mesirov, Jill P.
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2005)
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Journal Article
MicroRNA expression profiles classify human cancers
Golub, Todd R, Lu, Jun, Getz, Gad, Miska, Eric A, Alvarez-Saavedra, Ezequiel, Lamb, Justin, Peck, David, Sweet-Cordero, Alejandro, Ebert, Benjamin L, Mak, Raymond H, Ferrando, Adolfo A, Downing, James R, Jacks, Tyler, Horvitz, H. Robert
Published in Nature (09.06.2005)
Published in Nature (09.06.2005)
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Journal Article
Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals
Lander, Eric S, Kellis, Manolis, Xie, Xiaohui, Lu, Jun, Kulbokas, E. J, Golub, Todd R, Mootha, Vamsi, Lindblad-Toh, Kerstin
Published in Nature (17.03.2005)
Published in Nature (17.03.2005)
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Journal Article
BRAF mutation predicts sensitivity to MEK inhibition
Rosen, Neal, Solit, David B, Garraway, Levi A, Pratilas, Christine A, Sawai, Ayana, Getz, Gad, Basso, Andrea, Ye, Qing, Lobo, Jose M, She, Yuhong, Osman, Iman, Golub, Todd R, Sebolt-Leopold, Judith, Sellers, William R
Published in Nature (19.01.2006)
Published in Nature (19.01.2006)
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Journal Article
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
STANBROUGH, Michael, BUBLEY, Glenn J, ROSS, Kenneth, GOLUB, Todd R, RUBIN, Mark A, PENNING, Trevor M, FEBBO, Phillip G, BALK, Steven P
Published in Cancer research (Chicago, Ill.) (01.03.2006)
Published in Cancer research (Chicago, Ill.) (01.03.2006)
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Journal Article
A molecular signature of metastasis in primary solid tumors
Ramaswamy, Sridhar, Golub, Todd R, Ross, Ken N, Lander, Eric S
Published in Nature genetics (01.01.2003)
Published in Nature genetics (01.01.2003)
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Journal Article
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
Getz, Gad, Li, Cheng, Meyerson, Matthew L, Rimm, David L, Beroukhim, Rameen, Golub, Todd R, Widlund, Hans R, Granter, Scott R, Wagner, Stephan N, Sellers, William R, Milner, Danny A, Garraway, Levi A, Berger, Aaron J, Ramaswamy, Sridhar, Rubin, Mark A, Fisher, David E, Du, Jinyan, Lee, Charles
Published in Nature (07.07.2005)
Published in Nature (07.07.2005)
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Journal Article
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
Levine, Ross L., Wadleigh, Martha, Cools, Jan, Ebert, Benjamin L., Wernig, Gerlinde, Huntly, Brian J.P., Boggon, Titus J., Wlodarska, Iwona, Clark, Jennifer J., Moore, Sandra, Adelsperger, Jennifer, Koo, Sumin, Lee, Jeffrey C., Gabriel, Stacey, Mercher, Thomas, D’Andrea, Alan, Fröhling, Stefan, Döhner, Konstanze, Marynen, Peter, Vandenberghe, Peter, Mesa, Ruben A., Tefferi, Ayalew, Griffin, James D., Eck, Michael J., Sellers, William R., Meyerson, Matthew, Golub, Todd R., Lee, Stephanie J., Gilliland, D. Gary
Published in Cancer cell (01.04.2005)
Published in Cancer cell (01.04.2005)
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Journal Article
PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
Altshuler, David, Groop, Leif C, Mootha, Vamsi K, Lindgren, Cecilia M, Eriksson, Karl-Fredrik, Subramanian, Aravind, Sihag, Smita, Lehar, Joseph, Puigserver, Pere, Carlsson, Emma, Ridderstråle, Martin, Laurila, Esa, Houstis, Nicholas, Daly, Mark J, Patterson, Nick, Mesirov, Jill P, Golub, Todd R, Tamayo, Pablo, Spiegelman, Bruce, Lander, Eric S, Hirschhorn, Joel N
Published in Nature genetics (01.07.2003)
Published in Nature genetics (01.07.2003)
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Journal Article
Abstract P3-03-01: A novel high-throughput secreted factor screen and bioinformatics pipeline identifies microenvironment-derived FGF2 as a mechanism of resistance to anti-estrogens, PI3K, and mTOR inhibitors in ER+ breast cancer
Shee, K, Hinds, JW, Hampsch, RA, Golub, TR, Straussman, R, Miller, TW
Published in Cancer research (Chicago, Ill.) (15.02.2017)
Published in Cancer research (Chicago, Ill.) (15.02.2017)
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Journal Article
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis
Jacks, Tyler, Sweet-Cordero, Alejandro, Mukherjee, Sayan, Subramanian, Aravind, You, Han, Roix, Jeffrey J, Ladd-Acosta, Christine, Mesirov, Jill, Golub, Todd R
Published in Nature genetics (01.01.2005)
Published in Nature genetics (01.01.2005)
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Journal Article
Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response
Monti, Stefano, Savage, Kerry J., Kutok, Jeffery L., Feuerhake, Friedrich, Kurtin, Paul, Mihm, Martin, Wu, Bingyan, Pasqualucci, Laura, Neuberg, Donna, Aguiar, Ricardo C.T., Cin, Paola Dal, Ladd, Christine, Pinkus, Geraldine S., Salles, Gilles, Harris, Nancy Lee, Dalla-Favera, Riccardo, Habermann, Thomas M., Aster, Jon C., Golub, Todd R., Shipp, Margaret A.
Published in Blood (01.03.2005)
Published in Blood (01.03.2005)
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Journal Article
Tumor necrosis factor-α suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: Nuclear factor-κB activation by TNF-α is obligatory
HONG RUAN, HACOHEN, Nir, GOLUB, Todd R, VAN PARIJS, Luk, LODISH, Harvey F
Published in Diabetes (New York, N.Y.) (01.05.2002)
Published in Diabetes (New York, N.Y.) (01.05.2002)
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Journal Article
Estrogen-Dependent Signaling in a Molecularly Distinct Subclass of Aggressive Prostate Cancer
Setlur, Sunita R., Mertz, Kirsten D., Hoshida, Yujin, Demichelis, Francesca, Lupien, Mathieu, Perner, Sven, Sboner, Andrea, Pawitan, Yudi, Andrén, Ove, Johnson, Laura A., Tang, Jeff, Adami, Hans-Olov, Calza, Stefano, Chinnaiyan, Arul M., Rhodes, Daniel, Tomlins, Scott, Fall, Katja, Mucci, Lorelei A., Kantoff, Philip W., Stampfer, Meir J., Andersson, Swen-Olof, Varenhorst, Eberhard, Johansson, Jan-Erik, Brown, Myles, Golub, Todd R., Rubin, Mark A.
Published in JNCI : Journal of the National Cancer Institute (04.06.2008)
Published in JNCI : Journal of the National Cancer Institute (04.06.2008)
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Journal Article
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
Golub, Todd R, Korsmeyer, Stanley J, Armstrong, Scott A, Staunton, Jane E, Silverman, Lewis B, Pieters, Rob, den Boer, Monique L, Minden, Mark D, Sallan, Stephen E, Lander, Eric S
Published in Nature genetics (01.01.2002)
Published in Nature genetics (01.01.2002)
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Journal Article
The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma
Savage, Kerry J., Monti, Stefano, Kutok, Jeffery L., Cattoretti, Giorgio, Neuberg, Donna, de Leval, Laurence, Kurtin, Paul, Cin, Paola Dal, Ladd, Christine, Feuerhake, Friedrich, Aguiar, Ricardo C.T., Li, Sigui, Salles, Gilles, Berger, Francoise, Jing, Wen, Pinkus, Geraldine S., Habermann, Thomas, Dalla-Favera, Riccardo, Harris, Nancy Lee, Aster, Jon C., Golub, Todd R., Shipp, Margaret A.
Published in Blood (01.12.2003)
Published in Blood (01.12.2003)
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Journal Article
Gene expression correlates of clinical prostate cancer behavior
Singh, Dinesh, Febbo, Phillip G., Ross, Kenneth, Jackson, Donald G., Manola, Judith, Ladd, Christine, Tamayo, Pablo, Renshaw, Andrew A., D'Amico, Anthony V., Richie, Jerome P., Lander, Eric S., Loda, Massimo, Kantoff, Philip W., Golub, Todd R., Sellers, William R.
Published in Cancer cell (01.03.2002)
Published in Cancer cell (01.03.2002)
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Journal Article