Orthogonal Techniques to Study the Effect of pH, Sucrose, and Arginine Salts on Monoclonal Antibody Physical Stability and Aggregation During Long-Term Storage
Svilenov, Hristo L., Kulakova, Alina, Zalar, Matja, Golovanov, Alexander P., Harris, Pernille, Winter, Gerhard
Published in Journal of pharmaceutical sciences (01.01.2020)
Published in Journal of pharmaceutical sciences (01.01.2020)
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Arginine to Lysine Mutations Increase the Aggregation Stability of a Single-Chain Variable Fragment through Unfolded-State Interactions
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Published in Biochemistry (Easton) (13.08.2019)
Published in Biochemistry (Easton) (13.08.2019)
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The effect of arginine glutamate on the stability of monoclonal antibodies in solution
Kheddo, Priscilla, Tracka, Malgorzata, Armer, Jonathan, Dearman, Rebecca J., Uddin, Shahid, van der Walle, Christopher F., Golovanov, Alexander P.
Published in International journal of pharmaceutics (01.10.2014)
Published in International journal of pharmaceutics (01.10.2014)
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The effect of charge mutations on the stability and aggregation of a human single chain Fv fragment
Austerberry, James I., Dajani, Rana, Panova, Stanislava, Roberts, Dorota, Golovanov, Alexander P., Pluen, Alain, van der Walle, Christopher F., Uddin, Shahid, Warwicker, Jim, Derrick, Jeremy P., Curtis, Robin
Published in European journal of pharmaceutics and biopharmaceutics (01.06.2017)
Published in European journal of pharmaceutics and biopharmaceutics (01.06.2017)
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Stability of a high-concentration monoclonal antibody solution produced by liquid-liquid phase separation
Bramham, Jack E, Davies, Stephanie A, Podmore, Adrian, Golovanov, Alexander P
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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A Simple Method for Improving Protein Solubility and Long-Term Stability
Golovanov, Alexander P, Hautbergue, Guillaume M, Wilson, Stuart A, Lian, Lu-Yun
Published in Journal of the American Chemical Society (28.07.2004)
Published in Journal of the American Chemical Society (28.07.2004)
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Investigating Liquid–Liquid Phase Separation of a Monoclonal Antibody Using Solution-State NMR Spectroscopy: Effect of Arg·Glu and Arg·HCl
Kheddo, Priscilla, Bramham, Jack E, Dearman, Rebecca J, Uddin, Shahid, van der Walle, Christopher F, Golovanov, Alexander P
Published in Molecular pharmaceutics (07.08.2017)
Published in Molecular pharmaceutics (07.08.2017)
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Competitive and cooperative interactions mediate RNA transfer from herpesvirus saimiri ORF57 to the mammalian export adaptor ALYREF
Tunnicliffe, Richard B, Hautbergue, Guillaume M, Wilson, Stuart A, Kalra, Priti, Golovanov, Alexander P
Published in PLoS pathogens (01.02.2014)
Published in PLoS pathogens (01.02.2014)
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Lipopolysaccharide Structure and the Phenomenon of Low Endotoxin Recovery
Gorman, Amy, Golovanov, Alexander P.
Published in European journal of pharmaceutics and biopharmaceutics (01.11.2022)
Published in European journal of pharmaceutics and biopharmaceutics (01.11.2022)
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The Interaction of the Cellular Export Adaptor Protein Aly/REF with ICP27 Contributes to the Efficiency of Herpes Simplex Virus 1 mRNA Export
Tian, Xiaochen, Devi-Rao, Gayathri, Golovanov, Alexander P, Sandri-Goldin, Rozanne M
Published in Journal of Virology (01.07.2013)
Published in Journal of Virology (01.07.2013)
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Structural basis for the recognition of cellular mRNA export factor REF by herpes viral proteins HSV-1 ICP27 and HVS ORF57
Tunnicliffe, Richard B, Hautbergue, Guillaume M, Kalra, Priti, Jackson, Brian R, Whitehouse, Adrian, Wilson, Stuart A, Golovanov, Alexander P
Published in PLoS pathogens (01.01.2011)
Published in PLoS pathogens (01.01.2011)
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Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8
Hargous, Yann, Hautbergue, Guillaume M, Tintaru, Aura M, Skrisovska, Lenka, Golovanov, Alexander P, Stevenin, James, Lian, Lu-Yun, Wilson, Stuart A, Allain, Frédéric H-T
Published in The EMBO journal (01.11.2006)
Published in The EMBO journal (01.11.2006)
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