Strain-induced mechanotransduction through primary cilia, extracellular ATP, purinergic calcium signaling, and ERK1/2 transactivates CITED2 and downregulates MMP-1 and MMP-13 gene expression in chondrocytes
He, Z, Leong, D.J, Zhuo, Z, Majeska, R.J, Cardoso, L, Spray, D.C, Goldring, M.B, Cobelli, N.J, Sun, H.B
Published in Osteoarthritis and cartilage (01.05.2016)
Published in Osteoarthritis and cartilage (01.05.2016)
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Journal Article
Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis
Bradley, E.W, Carpio, L.R, McGee-Lawrence, M.E, Castillejo Becerra, C, Amanatullah, D.F, Ta, L.E, Otero, M, Goldring, M.B, Kakar, S, Westendorf, J.J
Published in Osteoarthritis and cartilage (01.06.2016)
Published in Osteoarthritis and cartilage (01.06.2016)
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Journal Article
Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin
Luan, Y., Ph.D., M.D, Kong, L., Ph.D., M.D, Howell, D.R., M.D, Ilalov, K., M.D, Fajardo, M., M.D, Bai, X.-H., M.D, Di Cesare, P.E., M.D, Goldring, M.B., Ph.D, Abramson, S.B., M.D, Liu, C.-J., Ph.D
Published in Osteoarthritis and cartilage (01.11.2008)
Published in Osteoarthritis and cartilage (01.11.2008)
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Journal Article
High density micromass cultures of a human chondrocyte cell line: A reliable assay system to reveal the modulatory functions of pharmacological agents
Greco, K.V., Iqbal, A.J., Rattazzi, L., Nalesso, G., Moradi-Bidhendi, N., Moore, A.R., Goldring, M.B., Dell’Accio, F., Perretti, M.
Published in Biochemical pharmacology (15.12.2011)
Published in Biochemical pharmacology (15.12.2011)
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Journal Article
Oxidative stress and status of antioxidant enzymes in children with Kashin–Beck disease
Wang, W, Wei, S, Luo, M, Yu, B, Cao, J, Yang, Z, Wang, Z, Goldring, M.B, Chen, J
Published in Osteoarthritis and cartilage (01.11.2013)
Published in Osteoarthritis and cartilage (01.11.2013)
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Journal Article
Endoglin differentially regulates TGF-β-induced Smad2/3 and Smad1/5 signalling and its expression correlates with extracellular matrix production and cellular differentiation state in human chondrocytes
Finnson, K.W, Parker, W.L, Chi, Y, Hoemann, C.D, Goldring, M.B, Antoniou, J, Philip, A
Published in Osteoarthritis and cartilage (01.11.2010)
Published in Osteoarthritis and cartilage (01.11.2010)
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Journal Article
The E74-like factor 3 (ELF3) suppresses type II collagen gene (COL2A1) transcription in chondrocytes by disrupting the SOX9 CBP/P300-mediated histone acetyl transferase activity
Otero, M, Peng, H, Tsuchimochi, K, Wondimu, E.B, Culley, K.L, Ijiri, K, Goldring, M.B
Published in Osteoarthritis and cartilage (01.04.2016)
Published in Osteoarthritis and cartilage (01.04.2016)
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Journal Article
ELF3 contributes to cartilage degradation by controlling the expression of MMP13 in vivo, in a surgical model of osteoarthritis in mice
Wondimu, E.B, Culley, K.L, Quinn, J, Chang, J, Dragomir, C.L, Plumb, D.A, Goldring, M.B, Otero, M
Published in Osteoarthritis and cartilage (01.04.2016)
Published in Osteoarthritis and cartilage (01.04.2016)
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Journal Article
Mice with a specific knockout of IKKalpha in adult chondrocytes display reduced cartilage degradation following surgical induction of osteoarthritis
Otero, M, Culley, K.L, Wondimu, E.B, Quinn, J, Chang, J, Dragomir, C.L, Marcu, K.B, Goldring, M.B
Published in Osteoarthritis and cartilage (01.04.2016)
Published in Osteoarthritis and cartilage (01.04.2016)
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Journal Article
Accelerated cartilage degradation and increased chondrocyte apoptosis in GADD45β knockout mice subjected to a surgical model of OA
Plumb, D.A, Dragomir, C.L, Quinn, J, Culley, K.L, Chang, J, Wondimu, E.B, Goldring, M.B, Otero, M
Published in Osteoarthritis and cartilage (01.04.2016)
Published in Osteoarthritis and cartilage (01.04.2016)
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Journal Article
Cited2-mediated chondroprotective effects via suppression of adipogenesis and proinflammatory medators in the infrapatellar fat pad
Leong, D.J, Xu, L, He, Z, Zhang, Z, Hardin, J.A, Majeska, R.J, Goldring, M.B, Cobelli, N.J, Sun, H.B
Published in Osteoarthritis and cartilage (01.04.2016)
Published in Osteoarthritis and cartilage (01.04.2016)
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Journal Article
Biochemical evidence for gap junctions and Cx43 expression in immortalized human chondrocyte cell line: a potential model in the study of cell communication in human chondrocytes
Gago-Fuentes, R, Carpintero-Fernandez, P, Goldring, M.B, Brink, P.R, Mayan, M.D, Blanco, F.J
Published in Osteoarthritis and cartilage (01.04.2014)
Published in Osteoarthritis and cartilage (01.04.2014)
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Journal Article
Neuropeptide regulation of chondrocyte gene expression
Bevan, D, Goldring, M.B, Clark, I, Donell, S, Gavrilovic, J
Published in Osteoarthritis and cartilage (01.04.2013)
Published in Osteoarthritis and cartilage (01.04.2013)
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Journal Article
Contribution of ELF3 to cartilage damage in a non-invasive mechanical loading mouse model with osteoarthritis-like pathology
Craveiro, V, Otero, M, Culley, K.L, Wondimu, E.B, van der Meulen, M, Bostrom, M, Goldring, M.B
Published in Osteoarthritis and cartilage (01.04.2015)
Published in Osteoarthritis and cartilage (01.04.2015)
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Journal Article
Hypoxia-inducible factor 3-alpha expression (HIF-3α) is associated with the stable chondrocyte phenotype and inhibits HIF-2α/ARNTL-mediated transactivation of matrix metalloproteinase-13
Markway, B.D, Cho, H, Anderson, D.E, Zilberman-Rudenko, J, Holden, P, McAlinden, A, Otero, M, Goldring, M.B, Johnstone, B
Published in Osteoarthritis and cartilage (01.04.2015)
Published in Osteoarthritis and cartilage (01.04.2015)
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Journal Article
Macroscopic synovial inflammation correlates with symptoms and cartilage degradation in middle-aged patients undergoing arthroscopic surgery for meniscal tear
Trisolino, G, Favero, M, Lazzaro, A, Martucci, E, Strazzari, A, Iacobellis, C, Cigolotti, A, Goldring, S.R, Goldring, M.B, Belluzzi, E, Grigolo, B, Olivotto, E
Published in Osteoarthritis and cartilage (01.04.2016)
Published in Osteoarthritis and cartilage (01.04.2016)
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Journal Article
Comparison between chondroprotective effects of glucosamine, curcumin, and diacerein in IL-1β-stimulated C-28/I2 chondrocytes
Toegel, S., M.Pharm.S., Ph.D, Wu, S.Q., M.Pharm.S, Piana, C., M.Pharm.S, Unger, F.M., Ph.D, Wirth, M., M.Pharm.S., Ph.D, Goldring, M.B., Ph.D, Gabor, F., M.Pharm.S., Ph.D, Viernstein, H., M.Pharm.S., Ph.D
Published in Osteoarthritis and cartilage (01.10.2008)
Published in Osteoarthritis and cartilage (01.10.2008)
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