Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes
Mirhadi, Shideh, Tam, Shirley, Li, Quan, Moghal, Nadeem, Pham, Nhu-An, Tong, Jiefei, Golbourn, Brian J, Krieger, Jonathan R, Taylor, Paul, Li, Ming, Weiss, Jessica, Martins-Filho, Sebastiao N, Raghavan, Vibha, Mamatjan, Yasin, Khan, Aafaque A, Cabanero, Michael, Sakashita, Shingo, Huo, Kugeng, Agnihotri, Sameer, Ishizawa, Kota, Waddell, Thomas K, Zadeh, Gelareh, Yasufuku, Kazuhiro, Liu, Geoffrey, Shepherd, Frances A, Moran, Michael F, Tsao, Ming-Sound
Published in Nature communications (05.04.2022)
Published in Nature communications (05.04.2022)
Get full text
Journal Article
Targeting mitochondrial energetics reverses panobinostat- and marizomib-induced resistance in pediatric and adult high-grade gliomas
Jane, Esther P, Reslink, Matthew C, Gatesman, Taylor A, Halbert, Matthew E, Miller, Tracy A, Golbourn, Brian J, Casillo, Stephanie M, Mullett, Steven J, Wendell, Stacy G, Obodo, Udochukwu, Mohanakrishnan, Dinesh, Dange, Riya, Michealraj, Antony, Brenner, Charles, Agnihotri, Sameer, Premkumar, Daniel R, Pollack, Ian F
Published in Molecular oncology (01.09.2023)
Published in Molecular oncology (01.09.2023)
Get full text
Journal Article
Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma
Faria, Claudia C, Golbourn, Brian J, Dubuc, Adrian M, Remke, Marc, Diaz, Roberto J, Agnihotri, Sameer, Luck, Amanda, Sabha, Nesrin, Olsen, Samantha, Wu, Xiaochong, Garzia, Livia, Ramaswamy, Vijay, Mack, Stephen C, Wang, Xin, Leadley, Michael, Reynaud, Denis, Ermini, Leonardo, Post, Martin, Northcott, Paul A, Pfister, Stefan M, Croul, Sidney E, Kool, Marcel, Korshunov, Andrey, Smith, Christian A, Taylor, Michael D, Rutka, James T
Published in Cancer research (Chicago, Ill.) (01.01.2015)
Published in Cancer research (Chicago, Ill.) (01.01.2015)
Get full text
Journal Article
A role for activated Cdc42 in glioblastoma multiforme invasion
Okura, Hidehiro, Golbourn, Brian J, Shahzad, Uswa, Agnihotri, Sameer, Sabha, Nesrin, Krieger, Jonathan R, Figueiredo, Carlyn A, Chalil, Alan, Landon-Brace, Natalie, Riemenschneider, Alexandra, Arai, Hajime, Smith, Christian A, Xu, Songli, Kaluz, Stefan, Marcus, Adam I, Van Meir, Erwin G, Rutka, James T
Published in Oncotarget (30.08.2016)
Published in Oncotarget (30.08.2016)
Get full text
Journal Article
Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma
Faria, Claudia C, Agnihotri, Sameer, Mack, Stephen C, Golbourn, Brian J, Diaz, Roberto J, Olsen, Samantha, Bryant, Melissa, Bebenek, Matthew, Wang, Xin, Bertrand, Kelsey C, Kushida, Michelle, Head, Renee, Clark, Ian, Dirks, Peter, Smith, Christian A, Taylor, Michael D, Rutka, James T
Published in Oncotarget (28.08.2015)
Published in Oncotarget (28.08.2015)
Get full text
Journal Article
ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
Arabzade, Amir, Zhao, Yanhua, Varadharajan, Srinidhi, Chen, Hsiao-Chi, Jessa, Selin, Rivas, Bryan, Stuckert, Austin J, Solis, Minerva, Kardian, Alisha, Tlais, Dana, Golbourn, Brian J, Stanton, Ann-Catherine J, Chan, Yuen San, Olson, Calla, Karlin, Kristen L, Kong, Kathleen, Kupp, Robert, Hu, Baoli, Injac, Sarah G, Ngo, Madeline, Wang, Peter R, De León, Luz A, Sahm, Felix, Kawauchi, Daisuke, Pfister, Stefan M, Lin, Charles Y, Hodges, H Courtney, Singh, Irtisha, Westbrook, Thomas F, Chintagumpala, Murali M, Blaney, Susan M, Parsons, Donald W, Pajtler, Kristian W, Agnihotri, Sameer, Gilbertson, Richard J, Yi, Joanna, Jabado, Nada, Kleinman, Claudia L, Bertrand, Kelsey C, Deneen, Benjamin, Mack, Stephen C
Published in Cancer discovery (01.09.2021)
Published in Cancer discovery (01.09.2021)
Get full text
Journal Article
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome
Golbourn, Brian J, Halbert, Matthew E, Halligan, Katharine, Varadharajan, Srinidhi, Krug, Brian, Mbah, Nneka E, Kabir, Nisha, Stanton, Ann-Catherine J, Locke, Abigail L, Casillo, Stephanie M, Zhao, Yanhua, Sanders, Lauren M, Cheney, Allison, Mullett, Steven J, Chen, Apeng, Wassell, Michelle, Andren, Anthony, Perez, Jennifer, Jane, Esther P, Premkumar, Daniel R David, Koncar, Robert F, Mirhadi, Shideh, McCarl, Lauren H, Chang, Yue-Fang, Wu, Yijen L, Gatesman, Taylor A, Cruz, Andrea F, Zapotocky, Michal, Hu, Baoli, Kohanbash, Gary, Wang, Xiuxing, Vartanian, Alenoush, Moran, Michael F, Lieberman, Frank, Amankulor, Nduka M, Wendell, Stacy G, Vaske, Olena M, Panigrahy, Ashok, Felker, James, Bertrand, Kelsey C, Kleinman, Claudia L, Rich, Jeremy N, Friedlander, Robert M, Broniscer, Alberto, Lyssiotis, Costas, Jabado, Nada, Pollack, Ian F, Mack, Stephen C, Agnihotri, Sameer
Published in Nature cancer (01.05.2022)
Published in Nature cancer (01.05.2022)
Get more information
Journal Article
FORETINIB IS EFFECTIVE THERAPY FOR METASTATIC SONIC HEDGEHOG MEDULLOBLASTOMA
Smith, C., Faria, C. C., Dubuc, A. M., Remke, M., Golbourn, B. J., Diaz, R. J., Agnihotri, S., Luck, A., Sabha, N., Olsen, S., Wu, X., Garzia, L., Ramaswamy, V., Mack, S. C., Wang, X., Leadley, M., Reynaud, D., Ermini, L., Post, M., Northcott, P. A., Pfister, S. M., Croul, S. E., Kool, M., Korshunov, A., Taylor, M. D., Rutka, J. T.
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2014)
Get full text
Journal Article
Abstract 4038: Role of the Rho-GTPase CDC42 in glioma migration
Okura, Hidehiro, Golbourn, Brian J., Luck, Amanda J., Smith, Christian A., Rutka, James T.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Get full text
Journal Article
An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma
Casillo, Stephanie M., Gatesman, Taylor A., Chilukuri, Akanksha, Varadharajan, Srinidhi, Johnson, Brenden J., David Premkumar, Daniel R., Jane, Esther P., Plute, Tritan J., Koncar, Robert F., Stanton, Ann-Catherine J., Biagi-Junior, Carlos A.O., Barber, Callie S., Halbert, Matthew E., Golbourn, Brian J., Halligan, Katharine, Cruz, Andrea F., Mansi, Neveen M., Cheney, Allison, Mullett, Steven J., Land, Clinton Van’t, Perez, Jennifer L., Myers, Max I., Agrawal, Nishant, Michel, Joshua J., Chang, Yue-Fang, Vaske, Olena M., MichaelRaj, Antony, Lieberman, Frank S., Felker, James, Shiva, Sruti, Bertrand, Kelsey C., Amankulor, Nduka, Hadjipanayis, Costas G., Abdullah, Kalil G., Zinn, Pascal O., Friedlander, Robert M., Abel, Taylor J., Nazarian, Javad, Venneti, Sriram, Filbin, Mariella G., Gelhaus, Stacy L., Mack, Stephen C., Pollack, Ian F., Agnihotri, Sameer
Published in Cell reports (Cambridge) (23.01.2024)
Published in Cell reports (Cambridge) (23.01.2024)
Get full text
Journal Article