Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma
Tawbi, Hussein A, Schadendorf, Dirk, Lipson, Evan J, Ascierto, Paolo A, Matamala, Luis, Castillo Gutiérrez, Erika, Rutkowski, Piotr, Gogas, Helen J, Lao, Christopher D, De Menezes, Juliana Janoski, Dalle, Stéphane, Arance, Ana, Grob, Jean-Jacques, Srivastava, Shivani, Abaskharoun, Mena, Hamilton, Melissa, Keidel, Sarah, Simonsen, Katy L, Sobiesk, Anne Marie, Li, Bin, Hodi, F. Stephen, Long, Georgina V
Published in The New England journal of medicine (06.01.2022)
Published in The New England journal of medicine (06.01.2022)
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Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutant melanoma (COLUMBUS): a multicentre, open-label, randomised phase 3 trial
Dummer, Reinhard, Ascierto, Paolo A, Gogas, Helen J, Arance, Ana, Mandala, Mario, Liszkay, Gabriella, Garbe, Claus, Schadendorf, Dirk, Krajsova, Ivana, Gutzmer, Ralf, Chiarion-Sileni, Vanna, Dutriaux, Caroline, de Groot, Jan Willem B, Yamazaki, Naoya, Loquai, Carmen, Moutouh-de Parseval, Laure A, Pickard, Michael D, Sandor, Victor, Robert, Caroline, Flaherty, Keith T
Published in The lancet oncology (01.05.2018)
Published in The lancet oncology (01.05.2018)
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Overall survival in patients with BRAF-mutant melanoma receiving encorafenib plus binimetinib versus vemurafenib or encorafenib (COLUMBUS): a multicentre, open-label, randomised, phase 3 trial
Dummer, Reinhard, Ascierto, Paolo A, Gogas, Helen J, Arance, Ana, Mandala, Mario, Liszkay, Gabriella, Garbe, Claus, Schadendorf, Dirk, Krajsova, Ivana, Gutzmer, Ralf, Chiarion Sileni, Vanna, Dutriaux, Caroline, de Groot, Jan Willem B, Yamazaki, Naoya, Loquai, Carmen, Moutouh-de Parseval, Laure A, Pickard, Michael D, Sandor, Victor, Robert, Caroline, Flaherty, Keith T
Published in The lancet oncology (01.10.2018)
Published in The lancet oncology (01.10.2018)
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COLUMBUS 5-Year Update: A Randomized, Open-Label, Phase III Trial of Encorafenib Plus Binimetinib Versus Vemurafenib or Encorafenib in Patients With BRAF V600-Mutant Melanoma
Dummer, Reinhard, Flaherty, Keith T, Robert, Caroline, Arance, Ana, de Groot, Jan Willem B, Garbe, Claus, Gogas, Helen J, Gutzmer, Ralf, Krajsová, Ivana, Liszkay, Gabriella, Loquai, Carmen, Mandalà, Mario, Schadendorf, Dirk, Yamazaki, Naoya, di Pietro, Alessandra, Cantey-Kiser, Jean, Edwards, Michelle, Ascierto, Paolo A
Published in Journal of clinical oncology (20.12.2022)
Published in Journal of clinical oncology (20.12.2022)
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Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma
Robert, Caroline, Grob, Jean J, Stroyakovskiy, Daniil, Karaszewska, Boguslawa, Hauschild, Axel, Levchenko, Evgeny, Chiarion Sileni, Vanna, Schachter, Jacob, Garbe, Claus, Bondarenko, Igor, Gogas, Helen, Mandalá, Mario, Haanen, John B.A.G, Lebbé, Celeste, Mackiewicz, Andrzej, Rutkowski, Piotr, Nathan, Paul D, Ribas, Antoni, Davies, Michael A, Flaherty, Keith T, Burgess, Paul, Tan, Monique, Gasal, Eduard, Voi, Maurizio, Schadendorf, Dirk, Long, Georgina V
Published in The New England journal of medicine (15.08.2019)
Published in The New England journal of medicine (15.08.2019)
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Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma
Liu, David, Schilling, Bastian, Liu, Derek, Sucker, Antje, Livingstone, Elisabeth, Jerby-Arnon, Livnat, Zimmer, Lisa, Gutzmer, Ralf, Satzger, Imke, Loquai, Carmen, Grabbe, Stephan, Vokes, Natalie, Margolis, Claire A., Conway, Jake, He, Meng Xiao, Elmarakeby, Haitham, Dietlein, Felix, Miao, Diana, Tracy, Adam, Gogas, Helen, Goldinger, Simone M., Utikal, Jochen, Blank, Christian U., Rauschenberg, Ricarda, von Bubnoff, Dagmar, Krackhardt, Angela, Weide, Benjamin, Haferkamp, Sebastian, Kiecker, Felix, Izar, Ben, Garraway, Levi, Regev, Aviv, Flaherty, Keith, Paschen, Annette, Van Allen, Eliezer M., Schadendorf, Dirk
Published in Nature medicine (01.12.2019)
Published in Nature medicine (01.12.2019)
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Update on tolerability and overall survival in COLUMBUS: landmark analysis of a randomised phase 3 trial of encorafenib plus binimetinib vs vemurafenib or encorafenib in patients with BRAF V600–mutant melanoma
Ascierto, Paolo A., Dummer, Reinhard, Gogas, Helen J., Flaherty, Keith T., Arance, Ana, Mandala, Mario, Liszkay, Gabriella, Garbe, Claus, Schadendorf, Dirk, Krajsova, Ivana, Gutzmer, Ralf, de Groot, Jan Willem B., Loquai, Carmen, Gollerkeri, Ashwin, Pickard, Michael D., Robert, Caroline
Published in European journal of cancer (1990) (01.02.2020)
Published in European journal of cancer (1990) (01.02.2020)
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Nivolumab in Previously Untreated Melanoma without BRAF Mutation
Robert, Caroline, Long, Georgina V, Brady, Benjamin, Dutriaux, Caroline, Maio, Michele, Mortier, Laurent, Hassel, Jessica C, Rutkowski, Piotr, McNeil, Catriona, Kalinka-Warzocha, Ewa, Savage, Kerry J, Hernberg, Micaela M, Lebbé, Celeste, Charles, Julie, Mihalcioiu, Catalin, Chiarion-Sileni, Vanna, Mauch, Cornelia, Cognetti, Francesco, Arance, Ana, Schmidt, Henrik, Schadendorf, Dirk, Gogas, Helen, Lundgren-Eriksson, Lotta, Horak, Christine, Sharkey, Brian, Waxman, Ian M, Atkinson, Victoria, Ascierto, Paolo A
Published in The New England journal of medicine (22.01.2015)
Published in The New England journal of medicine (22.01.2015)
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The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma
Van Allen, Eliezer M, Wagle, Nikhil, Sucker, Antje, Treacy, Daniel J, Johannessen, Cory M, Goetz, Eva M, Place, Chelsea S, Taylor-Weiner, Amaro, Whittaker, Steven, Kryukov, Gregory V, Hodis, Eran, Rosenberg, Mara, McKenna, Aaron, Cibulskis, Kristian, Farlow, Deborah, Zimmer, Lisa, Hillen, Uwe, Gutzmer, Ralf, Goldinger, Simone M, Ugurel, Selma, Gogas, Helen J, Egberts, Friederike, Berking, Carola, Trefzer, Uwe, Loquai, Carmen, Weide, Benjamin, Hassel, Jessica C, Gabriel, Stacey B, Carter, Scott L, Getz, Gad, Garraway, Levi A, Schadendorf, Dirk
Published in Cancer discovery (01.01.2014)
Published in Cancer discovery (01.01.2014)
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Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma
Weber, Jeffrey, Mandala, Mario, Del Vecchio, Michele, Gogas, Helen J, Arance, Ana M, Cowey, C. Lance, Dalle, Stéphane, Schenker, Michael, Chiarion-Sileni, Vanna, Marquez-Rodas, Ivan, Grob, Jean-Jacques, Butler, Marcus O, Middleton, Mark R, Maio, Michele, Atkinson, Victoria, Queirolo, Paola, Gonzalez, Rene, Kudchadkar, Ragini R, Smylie, Michael, Meyer, Nicolas, Mortier, Laurent, Atkins, Michael B, Long, Georgina V, Bhatia, Shailender, Lebbé, Celeste, Rutkowski, Piotr, Yokota, Kenji, Yamazaki, Naoya, Kim, Tae M, de Pril, Veerle, Sabater, Javier, Qureshi, Anila, Larkin, James, Ascierto, Paolo A
Published in The New England journal of medicine (09.11.2017)
Published in The New England journal of medicine (09.11.2017)
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Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions
Sucker, Antje, Zhao, Fang, Pieper, Natalia, Heeke, Christina, Maltaner, Raffaela, Stadtler, Nadine, Real, Birgit, Bielefeld, Nicola, Howe, Sebastian, Weide, Benjamin, Gutzmer, Ralf, Utikal, Jochen, Loquai, Carmen, Gogas, Helen, Klein-Hitpass, Ludger, Zeschnigk, Michael, Westendorf, Astrid M., Trilling, Mirko, Horn, Susanne, Schilling, Bastian, Schadendorf, Dirk, Griewank, Klaus G., Paschen, Annette
Published in Nature communications (31.05.2017)
Published in Nature communications (31.05.2017)
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Adverse events associated with encorafenib plus binimetinib in the COLUMBUS study: incidence, course and management
Gogas, Helen J., Flaherty, Keith T., Dummer, Reinhard, Ascierto, Paolo A., Arance, Ana, Mandala, Mario, Liszkay, Gabriella, Garbe, Claus, Schadendorf, Dirk, Krajsova, Ivana, Gutzmer, Ralf, Sileni, Vanna Chiarion, Dutriaux, Caroline, de Groot, Jan Willem B., Yamazaki, Naoya, Loquai, Carmen, Gollerkeri, Ashwin, Pickard, Michael D., Robert, Caroline
Published in European journal of cancer (1990) (01.09.2019)
Published in European journal of cancer (1990) (01.09.2019)
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Phase III Randomized Clinical Trial Comparing Tremelimumab With Standard-of-Care Chemotherapy in Patients With Advanced Melanoma
RIBAS, Antoni, KEFFORD, Richard, LORIGAN, Paul, KENDRA, Kari L, MAIO, Michele, TREFZER, Uwe, SMYLIE, Michael, MCARTHUR, Grant A, DRENO, Brigitte, NATHAN, Paul D, MACKIEWICZ, Jacek, KIRKWOOD, John M, MARSHALL, Margaret A, GOMEZ-NAVARRO, Jesus, BO HUANG, PAVLOV, Dmitri, HAUSCHILD, Axel, PUNT, Cornelis J. A, HAANEN, John B, MARMOL, Maribel, GARBE, Claus, GOGAS, Helen, SCHACHTER, Jacob, LINETTE, Gerald
Published in Journal of clinical oncology (10.02.2013)
Published in Journal of clinical oncology (10.02.2013)
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Contribution of MEK Inhibition to BRAF/MEK Inhibitor Combination Treatment of BRAF -Mutant Melanoma: Part 2 of the Randomized, Open-Label, Phase III COLUMBUS Trial
Ascierto, Paolo A, Dummer, Reinhard, Gogas, Helen J, Arance, Ana, Mandala, Mario, Liszkay, Gabriella, Garbe, Claus, Schadendorf, Dirk, Krajsova, Ivana, Gutzmer, Ralf, Chiarion-Sileni, Vanna, Dutriaux, Caroline, de Groot, Jan Willem B, Yamazaki, Naoya, Loquai, Carmen, Robert, Caroline, Flaherty, Keith T
Published in Journal of clinical oncology (10.10.2023)
Published in Journal of clinical oncology (10.10.2023)
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Reactivation of tuberculosis in cancer patients following administration of immune checkpoint inhibitors: current evidence and clinical practice recommendations
Anastasopoulou, Amalia, Ziogas, Dimitrios C, Samarkos, Michael, Kirkwood, John M, Gogas, Helen
Published in Journal for immunotherapy of cancer (04.09.2019)
Published in Journal for immunotherapy of cancer (04.09.2019)
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Neoadjuvant treatment in ovarian cancer: New perspectives, new challenges
Nikolaidi, Adamantia, Fountzilas, Elena, Fostira, Florentia, Psyrri, Amanda, Gogas, Helen, Papadimitriou, Christos
Published in Frontiers in oncology (26.07.2022)
Published in Frontiers in oncology (26.07.2022)
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COLUMBUS 7-year update: A randomized, open-label, phase III trial of encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF V600E/K-mutant melanoma
Schadendorf, Dirk, Dummer, Reinhard, Flaherty, Keith T., Robert, Caroline, Arance, Ana, de Groot, Jan Willem B., Garbe, Claus, Gogas, Helen J., Gutzmer, Ralf, Krajsová, Ivana, Liszkay, Gabriella, Loquai, Carmen, Mandalà, Mario, Yamazaki, Naoya, Queirolo, Paola, Guenzel, Carolin, Polli, Anna, Thakur, Mahgull, di Pietro, Alessandra, Ascierto, Paolo A.
Published in European journal of cancer (1990) (01.06.2024)
Published in European journal of cancer (1990) (01.06.2024)
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Obesity and risk of malignant melanoma: A meta-analysis of cohort and case–control studies
Sergentanis, Theodoros N, Antoniadis, Antonios G, Gogas, Helen J, Antonopoulos, Constantine N, Adami, Hans-Olov, Ekbom, Anders, Petridou, Eleni Th
Published in European journal of cancer (1990) (01.02.2013)
Published in European journal of cancer (1990) (01.02.2013)
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Next Generation of Immunotherapy for Melanoma
KIRKWOOD, John M, TARHINI, Ahmad A, PANELLI, Monica C, MOSCHOS, Stergios J, ZAROUR, Hassane M, BUTTERFIELD, Lisa H, GOGAS, Helen J
Published in Journal of clinical oncology (10.07.2008)
Published in Journal of clinical oncology (10.07.2008)
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