There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments
Rapedius, Markus, Obergrussberger, Alison, Humphries, Edward S A, Scholz, Stephanie, Rinke-Weiss, Ilka, Goetze, Tom A, Brinkwirth, Nina, Rotordam, Maria Giustina, Strassmaier, Tim, Randolph, Aaron, Friis, Søren, Liutkute, Aiste, Seibertz, Fitzwilliam, Voigt, Niels, Fertig, Niels
Published in Frontiers in molecular neuroscience (22.08.2022)
Published in Frontiers in molecular neuroscience (22.08.2022)
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An update on the advancing high-throughput screening techniques for patch clamp-based ion channel screens: implications for drug discovery
Obergrussberger, Alison, Goetze, Tom A, Brinkwirth, Nina, Becker, Nadine, Friis, Søren, Rapedius, Markus, Haarmann, Claudia, Rinke-Weiß, Ilka, Stölzle-Feix, Sonja, Brüggemann, Andrea, George, Michael, Fertig, Niels
Published in Expert opinion on drug discovery (04.03.2018)
Published in Expert opinion on drug discovery (04.03.2018)
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Journal Article
Characterization of Tic110, a Channel-forming Protein at the Inner Envelope Membrane of Chloroplasts, Unveils a Response to Ca2+ and a Stromal Regulatory Disulfide Bridge
Balsera, Mónica, Goetze, Tom A., Kovács-Bogdán, Erika, Schürmann, Peter, Wagner, Richard, Buchanan, Bob B., Soll, Jürgen, Bölter, Bettina
Published in The Journal of biological chemistry (30.01.2009)
Published in The Journal of biological chemistry (30.01.2009)
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Journal Article
Structural model of FeoB, the iron transporter from Pseudomonas aeruginosa, predicts a cysteine lined, GTP-gated pore
Seyedmohammad, Saeed, Fuentealba, Natalia Alveal, Marriott, Robert A J, Goetze, Tom A, Edwardson, J Michael, Barrera, Nelson P, Venter, Henrietta
Published in Bioscience reports (01.04.2016)
Published in Bioscience reports (01.04.2016)
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Journal Article
Automated Patch Clamp Meets High-Throughput Screening: 384 Cells Recorded in Parallel on a Planar Patch Clamp Module
Obergrussberger, Alison, Brüggemann, Andrea, Goetze, Tom A., Rapedius, Markus, Haarmann, Claudia, Rinke, Ilka, Becker, Nadine, Oka, Takayuki, Ohtsuki, Atsushi, Stengel, Timo, Vogel, Marius, Steindl, Juergen, Mueller, Max, Stiehler, Johannes, George, Michael, Fertig, Niels
Published in Journal of Laboratory Automation (01.12.2016)
Published in Journal of Laboratory Automation (01.12.2016)
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Visualization of Structural Changes Accompanying Activation of N-Methyl-d-aspartate (NMDA) Receptors Using Fast-scan Atomic Force Microscopy Imaging
Suzuki, Yuki, Goetze, Tom A., Stroebel, David, Balasuriya, Dilshan, Yoshimura, Shige H., Henderson, Robert M., Paoletti, Pierre, Takeyasu, Kunio, Edwardson, J. Michael
Published in The Journal of biological chemistry (11.01.2013)
Published in The Journal of biological chemistry (11.01.2013)
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Journal Article
Direct evidence for functional TRPV1/TRPA1 heteromers
Fischer, Michael J. M., Balasuriya, Dilshan, Jeggle, Pia, Goetze, Tom A., McNaughton, Peter A., Reeh, Peter W., Edwardson, J. Michael
Published in Pflügers Archiv (01.12.2014)
Published in Pflügers Archiv (01.12.2014)
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Journal Article
The suitability of high throughput automated patch clamp for physiological applications
Obergrussberger, Alison, Rinke‐Weiß, Ilka, Goetze, Tom A., Rapedius, Markus, Brinkwirth, Nina, Becker, Nadine, Rotordam, Maria Giustina, Hutchison, Laura, Madau, Paola, Pau, Davide, Dalrymple, David, Braun, Nina, Friis, Søren, Pless, Stephan A., Fertig, Niels
Published in The Journal of physiology (01.01.2022)
Published in The Journal of physiology (01.01.2022)
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Journal Article
Direct evidence for functional TRPV1/TRPA1 heteromers
Fischer, Michael J. M., Balasuriya, Dilshan, Jeggle, Pia, Goetze, Tom A., McNaughton, Peter A., Reeh, Peter W., Edwardson, J. Michael
Published in Pflügers Archiv (01.12.2014)
Published in Pflügers Archiv (01.12.2014)
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Journal Article
Reliable identification of cardiac conduction abnormalities in drug discovery using automated patch clamp II: Best practices for Nav1.5 peak current in a high throughput screening environment
Rotordam, Maria Giustina, Obergrussberger, Alison, Brinkwirth, Nina, Takasuna, Kiyoshi, Becker, Nadine, Horváth, András, Goetze, Tom A., Rapedius, Markus, Furukawa, Hatsue, Hasegawa, Yuka, Oka, Takayuki, Fertig, Niels, Stoelzle-Feix, Sonja
Published in Journal of pharmacological and toxicological methods (01.11.2021)
Published in Journal of pharmacological and toxicological methods (01.11.2021)
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A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm
Ridder, Bradley J., Leishman, Derek J., Bridgland-Taylor, Matthew, Samieegohar, Mohammadreza, Han, Xiaomei, Wu, Wendy W., Randolph, Aaron, Tran, Phu, Sheng, Jiansong, Danker, Timm, Lindqvist, Anders, Konrad, Daniel, Hebeisen, Simon, Polonchuk, Liudmila, Gissinger, Evgenia, Renganathan, Muthukrishnan, Koci, Bryan, Wei, Haiyang, Fan, Jingsong, Levesque, Paul, Kwagh, Jae, Imredy, John, Zhai, Jin, Rogers, Marc, Humphries, Edward, Kirby, Robert, Stoelzle-Feix, Sonja, Brinkwirth, Nina, Rotordam, Maria Giustina, Becker, Nadine, Friis, Søren, Rapedius, Markus, Goetze, Tom A., Strassmaier, Tim, Okeyo, George, Kramer, James, Kuryshev, Yuri, Wu, Caiyun, Himmel, Herbert, Mirams, Gary R., Strauss, David G., Bardenet, Rémi, Li, Zhihua
Published in Toxicology and applied pharmacology (01.05.2020)
Published in Toxicology and applied pharmacology (01.05.2020)
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Journal Article
Characterization of Tic110, a channel-forming protein at the inner envelope membrane of chloroplasts, unveils a response to Ca(2+) and a stromal regulatory disulfide bridge
Balsera, Mónica, Goetze, Tom A, Kovács-Bogdán, Erika, Schürmann, Peter, Wagner, Richard, Buchanan, Bob B, Soll, Jürgen, Bölter, Bettina
Published in The Journal of biological chemistry (30.01.2009)
Published in The Journal of biological chemistry (30.01.2009)
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Journal Article
Identification of Drug-Drug Interactions In Vitro: A Case Study Evaluating the Effects of Sofosbuvir and Amiodarone on hiPSC-Derived Cardiomyocytes
Millard, Daniel C, Strock, Christopher J, Carlson, Coby B, Aoyama, Natsuyo, Juhasz, Krisztina, Goetze, Tom A, Stoelzle-Feix, Sonja, Becker, Nadine, Fertig, Niels, January, Craig T, Anson, Blake D, Ross, James D
Published in Toxicological sciences (01.11.2016)
Published in Toxicological sciences (01.11.2016)
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Journal Article
A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model
Han, Xiaomei, Samieegohar, Mohammadreza, Ridder, Bradley J., Wu, Wendy W., Randolph, Aaron, Tran, Phu, Sheng, Jiansong, Stoelzle-Feix, Sonja, Brinkwirth, Nina, Rotordam, Maria Giustina, Becker, Nadine, Friis, Søren, Rapedius, Markus, Goetze, Tom A., Strassmaier, Tim, Okeyo, George, Kramer, James, Kuryshev, Yuri, Wu, Caiyun, Strauss, David G., Li, Zhihua
Published in Journal of pharmacological and toxicological methods (01.09.2020)
Published in Journal of pharmacological and toxicological methods (01.09.2020)
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Journal Article
Corrigendum to “A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm” [Toxicology and Applied Pharmacology volume 394C (2020) 114961]
Ridder, Bradley J., Leishman, Derek J., Bridgland-Taylor, Matthew, Samieegohar, Mohammadreza, Han, Xiaomei, Wu, Wendy W., Randolph, Aaron, Tran, Phu, Sheng, Jiansong, Danker, Timm, Lindqvist, Anders, Konrad, Daniel, Hebeisen, Simon, Polonchuk, Liudmila, Gissinger, Evgenia, Renganathan, Muthukrishnan, Koci, Bryan, Wei, Haiyang, Fan, Jingsong, Levesque, Paul, Kwagh, Jae, Imredy, John, Zhai, Jin, Rogers, Marc, Humphries, Edward, Kirby, Robert, Stoelzle-Feix, Sonja, Brinkwirth, Nina, Rotordam, Maria Giustina, Becker, Nadine, Friis, Søren, Rapedius, Markus, Goetze, Tom A., Strassmaier, Tim, Okeyo, George, Kramer, James, Kuryshev, Yuri, Wu, Caiyun, Himmel, Herbert, Mirams, Gary R., Strauss, David G., Bardenet, Remi, Li, Zhihua
Published in Toxicology and applied pharmacology (15.05.2020)
Published in Toxicology and applied pharmacology (15.05.2020)
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α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid (AMPA) and N-Methyl-d-aspartate (NMDA) Receptors Adopt Different Subunit Arrangements
Balasuriya, Dilshan, Goetze, Tom A., Barrera, Nelson P., Stewart, Andrew P., Suzuki, Yuki, Edwardson, J. Michael
Published in The Journal of biological chemistry (26.07.2013)
Published in The Journal of biological chemistry (26.07.2013)
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Journal Article
Synthetic Self-Assembling Clostridial Chimera for Modulation of Sensory Functions
Ferrari, Enrico, Gu, Chunjing, Niranjan, Dhevahi, Restani, Laura, Rasetti-Escargueil, Christine, Obara, Ilona, Geranton, Sandrine M, Arsenault, Jason, Goetze, Tom A, Harper, Callista B, Nguyen, Tam H, Maywood, Elizabeth, O’Brien, John, Schiavo, Giampietro, Wheeler, Daniel W, Meunier, Frederic A, Hastings, Michael, Edwardson, J. Michael, Sesardic, Dorothea, Caleo, Matteo, Hunt, Stephen P, Davletov, Bazbek
Published in Bioconjugate chemistry (16.10.2013)
Published in Bioconjugate chemistry (16.10.2013)
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Journal Article
Pharmacology of P2X3 and P2X2/3 receptors: An automated patch clamp study
Sirtori, Elena, Rolland, Jean-Francois, Budusan, Elena L., Rotordam, Giustina M., Goetze, Tom A., Becker, Nadine, Obergrussberger, Alison, Strassmaier, Timothy, Bruggemann, Andrea, George, Michael, Fertig, Niels
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
Activation and Inhibition of Assay-Ready TRPA1 and TRPV Cells: An Automated Patch Clamp Study
Bruggemann, Andrea, Goetze, Tom A., Horváth, András, Rinke, Ilka, Becker, Nadine, Obergrussberger, Alison, Focke, Lukas, Wehmeier, Oliver, Schwandner, Ralf, Fertig, Niels
Published in Biophysical journal (12.02.2021)
Published in Biophysical journal (12.02.2021)
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Journal Article
Pharmacology of P2X 3 and P2X 2/3 receptors: An automated patch clamp study
Sirtori, Elena, Rolland, Jean-Francois, Budusan, Elena L, Rotordam, Giustina M, Goetze, Tom A, Becker, Nadine, Obergrussberger, Alison, Strassmaier, Timothy, Bruggemann, Andrea, George, Michael, Fertig, Niels
Published in Biophysical journal (10.02.2023)
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Published in Biophysical journal (10.02.2023)
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