Kinase activities in pancreatic ductal adenocarcinoma with prognostic and therapeutic avenues
Vallés‐Martí, Andrea, Goeij‐de Haas, Richard R., Henneman, Alex A., Piersma, Sander R., Pham, Thang V., Knol, Jaco C., Verheij, Joanne, Dijk, Frederike, Halfwerk, Hans, Giovannetti, Elisa, Jiménez, Connie R., Bijlsma, Maarten F.
Published in Molecular oncology (01.08.2024)
Published in Molecular oncology (01.08.2024)
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Phosphoproteomic Analysis of FLCN Inactivation Highlights Differential Kinase Pathways and Regulatory TFEB Phosphoserines
Glykofridis, Iris E., Henneman, Alex A., Balk, Jesper A., Goeij-de Haas, Richard, Westland, Denise, Piersma, Sander R., Knol, Jaco C., Pham, Thang V., Boekhout, Michiel, Zwartkruis, Fried J.T., Wolthuis, Rob M.F., Jimenez, Connie R.
Published in Molecular & cellular proteomics (01.09.2022)
Published in Molecular & cellular proteomics (01.09.2022)
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Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling
Verweij, Frederik Johannes, Bebelman, Maarten P, Jimenez, Connie R, Garcia-Vallejo, Juan J, Janssen, Hans, Neefjes, Jacques, Knol, Jaco C, de Goeij-de Haas, Richard, Piersma, Sander R, Baglio, S Rubina, Verhage, Matthijs, Middeldorp, Jaap M, Zomer, Anoek, van Rheenen, Jacco, Coppolino, Marc G, Hurbain, Ilse, Raposo, Graça, Smit, Martine J, Toonen, Ruud F G, van Niel, Guillaume, Pegtel, D Michiel
Published in The Journal of cell biology (05.03.2018)
Published in The Journal of cell biology (05.03.2018)
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Selective targeting of ligand-dependent and -independent signaling by GPCR conformation-specific anti-US28 intrabodies
De Groof, Timo W. M., Bergkamp, Nick D., Heukers, Raimond, Giap, Truc, Bebelman, Maarten P., Goeij-de Haas, Richard, Piersma, Sander R., Jimenez, Connie R., Garcia, K. Christopher, Ploegh, Hidde L., Siderius, Marco, Smit, Martine J.
Published in Nature communications (16.07.2021)
Published in Nature communications (16.07.2021)
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Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies
Cordo’, Valentina, Meijer, Mariska T., Hagelaar, Rico, de Goeij-de Haas, Richard R., Poort, Vera M., Henneman, Alex A., Piersma, Sander R., Pham, Thang V., Oshima, Koichi, Ferrando, Adolfo A., Zaman, Guido J. R., Jimenez, Connie R., Meijerink, Jules P. P.
Published in Nature communications (25.02.2022)
Published in Nature communications (25.02.2022)
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AAMP and MTSS1 Are Novel Negative Regulators of Endothelial Barrier Function Identified in a Proteomics Screen
Podieh, Fabienne, Overboom, Max C, Knol, Jaco C, Piersma, Sander R, Goeij-de Haas, Richard, Pham, Thang V, Jimenez, Connie R, Hordijk, Peter L
Published in Cells (Basel, Switzerland) (25.09.2024)
Published in Cells (Basel, Switzerland) (25.09.2024)
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Advancing wide implementation of precision oncology: A liquid nitrogen‐free snap freezer preserves molecular profiles of biological samples
Wijngaart, Hanneke, Jagga, Sahil, Dekker, Henk, Goeij, Richard, Piersma, Sander R., Pham, Thang V., Knol, Jaco C., Zonderhuis, Babs M., Holland, Harry J., Jiménez, Connie R., Verheul, Henk M. W., Vanapalli, Srinivas, Labots, Mariette
Published in Cancer medicine (Malden, MA) (01.05.2023)
Published in Cancer medicine (Malden, MA) (01.05.2023)
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Phosphoproteomics guides effective low-dose drug combinations against pancreatic ductal adenocarcinoma
Vallés-Martí, Andrea, Mantini, Giulia, Manoukian, Paul, Waasdorp, Cynthia, Sarasqueta, Arantza Fariña, de Goeij-de Haas, Richard R., Henneman, Alex A., Piersma, Sander R., Pham, Thang V., Knol, Jaco C., Giovannetti, Elisa, Bijlsma, Maarten F., Jiménez, Connie R.
Published in Cell reports (Cambridge) (27.06.2023)
Published in Cell reports (Cambridge) (27.06.2023)
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Phosphotyrosine-based-phosphoproteomics scaled-down to biopsy level for analysis of individual tumor biology and treatment selection
Labots, Mariette, van der Mijn, Johannes C., Beekhof, Robin, Piersma, Sander R., de Goeij-de Haas, Richard R., Pham, Thang V., Knol, Jaco C., Dekker, Henk, van Grieken, Nicole C.T., Verheul, Henk M.W., Jiménez, Connie R.
Published in Journal of proteomics (06.06.2017)
Published in Journal of proteomics (06.06.2017)
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Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell- Specific STAT Signaling After α2-3-Linked Sialic Acid Ligand Binding
Li, Rui-Jún Eveline, de Haas, Aram, Rodríguez, Ernesto, Kalay, Hakan, Zaal, Anouk, Jimenez, Connie R, Piersma, Sander R, Pham, Thang V, Henneman, Alex A, de Goeij-de Haas, Richard R, van Vliet, Sandra J, van Kooyk, Yvette
Published in Frontiers in immunology (22.04.2021)
Published in Frontiers in immunology (22.04.2021)
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Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients
Buffart, Tineke E, van den Oord, Rosanne A H M, van den Berg, Adriënne, Hilhorst, Riet, Bastiaensen, Niek, Pruijt, Hans F M, van den Brule, Adriaan, Nooijen, Peet, Labots, Mariette, de Goeij-de Haas, Richard R, Dekker, Henk, Piersma, Sander R, Pham, Thang V, van der Leij, Theo, de Wijn, Rik, Ruijtenbeek, Rob, Jiménez, Connie R, Verheul, Henk M W
Published in Clinical proteomics (18.02.2021)
Published in Clinical proteomics (18.02.2021)
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VRK1 Regulates Sensitivity to Oxidative Stress by Altering Histone Epigenetic Modifications and the Nuclear Phosphoproteome in Tumor Cells
Navarro-Carrasco, Elena, Monte-Serrano, Eva, Campos-Díaz, Aurora, Rolfs, Frank, de Goeij-de Haas, Richard, Pham, Thang V, Piersma, Sander R, González-Alonso, Paula, Jiménez, Connie R, Lazo, Pedro A
Published in International journal of molecular sciences (01.05.2024)
Published in International journal of molecular sciences (01.05.2024)
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IGF1R signaling induces epithelial-mesenchymal plasticity via ITGAV in cutaneous carcinoma
Lopez-Cerda, Marta, Lorenzo-Sanz, Laura, da Silva-Diz, Victoria, Llop, Sandra, Penin, Rosa M, Bermejo, Josep Oriol, de Goeij-de Haas, Richard, Piersma, Sander R, Pham, Thang V, Jimenez, Connie R, Martin-Liberal, Juan, Muñoz, Purificación
Published in Journal of experimental & clinical cancer research (29.07.2024)
Published in Journal of experimental & clinical cancer research (29.07.2024)
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Truncated FGFR2 is a clinically actionable oncogene in multiple cancers
Zingg, Daniel, Bhin, Jinhyuk, Yemelyanenko, Julia, Kas, Sjors M., Rolfs, Frank, Lutz, Catrin, Lee, Jessica K., Klarenbeek, Sjoerd, Silverman, Ian M., Annunziato, Stefano, Chan, Chang S., Piersma, Sander R., Eijkman, Timo, Badoux, Madelon, Gogola, Ewa, Siteur, Bjørn, Sprengers, Justin, de Klein, Bim, de Goeij-de Haas, Richard R., Riedlinger, Gregory M., Ke, Hua, Madison, Russell, Drenth, Anne Paulien, van der Burg, Eline, Schut, Eva, Henneman, Linda, van Miltenburg, Martine H., Proost, Natalie, Zhen, Huiling, Wientjens, Ellen, de Bruijn, Roebi, de Ruiter, Julian R., Boon, Ute, de Korte-Grimmerink, Renske, van Gerwen, Bastiaan, Féliz, Luis, Abou-Alfa, Ghassan K., Ross, Jeffrey S., van de Ven, Marieke, Rottenberg, Sven, Cuppen, Edwin, Chessex, Anne Vaslin, Ali, Siraj M., Burn, Timothy C., Jimenez, Connie R., Ganesan, Shridar, Wessels, Lodewyk F. A., Jonkers, Jos
Published in Nature (London) (18.08.2022)
Published in Nature (London) (18.08.2022)
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Human Testis Phosphoproteome Reveals Kinases as Potential Targets in Spermatogenesis and Testicular Cancer
Castillo, Judit, Knol, Jaco C., Korver, Cindy M., Piersma, Sander R., Pham, Thang V., de Goeij-de Haas, Richard R., van Pelt, Ans M.M., Jimenez, Connie R., Jansen, Bastiaan J.H.
Published in Molecular & cellular proteomics (15.03.2019)
Published in Molecular & cellular proteomics (15.03.2019)
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Western diet triggers cardiac dysfunction in heterozygous Mybpc3-targeted knock-in mice: A two-hit model of hypertrophic cardiomyopathy
Nollet, Edgar E., Algül, Sila, Goebel, Max, Schlossarek, Saskia, van der Wel, Nicole N., Jans, Judith J.M., van de Wiel, Mark A., Knol, Jaco C., Pham, Thang V., Piersma, Sander R., de Goeij-de Haas, Richard, Hermans, Jill, van Klinken, Jan Bert, van Weeghel, Michel, Houtkooper, Riekelt H., Carrier, Lucie, Jimenez, Connie R., Kuster, Diederik W.D., van der Velden, Jolanda
Published in Journal of Molecular and Cellular Cardiology Plus (Online) (01.12.2023)
Published in Journal of Molecular and Cellular Cardiology Plus (Online) (01.12.2023)
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Journal Article
Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers
Zingg, Daniel, Bhin, Jinhyuk, Yemelyanenko, Julia, Kas, Sjors M., Rolfs, Frank, Lutz, Catrin, Lee, Jessica K., Klarenbeek, Sjoerd, Silverman, Ian M., Annunziato, Stefano, Chan, Chang S., Piersma, Sander R., Eijkman, Timo, Badoux, Madelon, Gogola, Ewa, Siteur, Bjørn, Sprengers, Justin, de Klein, Bim, de Goeij-de Haas, Richard R., Riedlinger, Gregory M., Ke, Hua, Madison, Russell, Drenth, Anne Paulien, van der Burg, Eline, Schut, Eva, Henneman, Linda, van Miltenburg, Martine H., Proost, Natalie, Zhen, Huiling, Wientjens, Ellen, de Bruijn, Roebi, de Ruiter, Julian R., Boon, Ute, de Korte-Grimmerink, Renske, van Gerwen, Bastiaan, Féliz, Luis, Abou-Alfa, Ghassan K., Ross, Jeffrey S., van de Ven, Marieke, Rottenberg, Sven, Cuppen, Edwin, Chessex, Anne Vaslin, Ali, Siraj M., Burn, Timothy C., Jimenez, Connie R., Ganesan, Shridar, Wessels, Lodewyk F. A., Jonkers, Jos
Published in Nature (London) (29.09.2022)
Published in Nature (London) (29.09.2022)
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Abstract 4010: Identification of signaling pathways involved in colorectal adenoma-to-carcinoma progression using phosphoproteomics
Kemp, Sanne Martens-de, Henneman, Alex, Haas, Richard de Goeij-de, Piersma, Sander, Pham, Thang, Meijer, Gerrit, Carvalho, Beatriz, Jimenez, Connie
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy
Algül, Sila, Schuldt, Maike, Manders, Emmy, Jansen, Valentijn, Schlossarek, Saskia, de Goeij-de Haas, Richard, Henneman, Alex A, Piersma, Sander R, Jimenez, Connie R, Michels, Michelle, Carrier, Lucie, Helmes, Michiel, van der Velden, Jolanda, Kuster, Diederik W D
Published in Circulation research (18.08.2023)
Published in Circulation research (18.08.2023)
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Phospho-Proteomic Profiling of T-Cell Acute Lymphoblastic Leukemia Identifies Targetable Kinase Activities and Novel Treatment Combination Strategies
Cordo', Valentina, Hagelaar, Rico, Piersma, Sander, Goeij-de Haas, Richard, Pham, Thang V, Dylus, Jelle, Zaman, Guido, Jimenez, Connie, Meijerink, Jules P.P.
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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