Tricyclic Covalent Inhibitors Selectively Target Jak3 through an Active Site Thiol
Goedken, Eric R., Argiriadi, Maria A., Banach, David L., Fiamengo, Bryan A., Foley, Sage E., Frank, Kristine E., George, Jonathan S., Harris, Christopher M., Hobson, Adrian D., Ihle, David C., Marcotte, Douglas, Merta, Philip J., Michalak, Mark E., Murdock, Sara E., Tomlinson, Medha J., Voss, Jeffrey W.
Published in The Journal of biological chemistry (20.02.2015)
Published in The Journal of biological chemistry (20.02.2015)
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Examination of AVPR1a as an autism susceptibility gene
WASSINK, T. H, PIVEN, J, VIELAND, V. J, PIETILA, J, GOEDKEN, R. J, FOLSTEIN, S. E, SHEFFIELD, V. C
Published in Molecular psychiatry (01.10.2004)
Published in Molecular psychiatry (01.10.2004)
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Identification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal site
Goedken, Eric R., Argiriadi, Maria A., Dietrich, Justin D., Petros, Andrew M., Krishnan, Navasona, Panchal, Sanjay C., Qiu, Wei, Wu, Haihong, Zhu, Haizhong, Adams, Ashley M., Bodelle, Pierre M., Goguen, Lucas, Richardson, Paul L., Slivka, Peter F., Srikumaran, Myron, Upadhyay, Anup K., Wu, Bainan, Judge, Russell A., Vasudevan, Anil, Gopalakrishnan, Sujatha M., Cox, Philip B., Stoll, Vincent S., Sun, Chaohong
Published in Scientific reports (26.08.2022)
Published in Scientific reports (26.08.2022)
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ABBV-105, a selective and irreversible inhibitor of Bruton's tyrosine kinase, is efficacious in multiple preclinical models of inflammation
Goess, Christian, Harris, Christopher M., Murdock, Sara, McCarthy, Richard W., Sampson, Erik, Twomey, Rachel, Mathieu, Suzanne, Mario, Regina, Perham, Matthew, Goedken, Eric R., Long, Andrew J.
Published in Modern rheumatology (04.05.2019)
Published in Modern rheumatology (04.05.2019)
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Analysis of the role of PCNA-DNA contacts during clamp loading
McNally, Randall, Bowman, Gregory D, Goedken, Eric R, O'Donnell, Mike, Kuriyan, John
Published in BMC structural biology (30.01.2010)
Published in BMC structural biology (30.01.2010)
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Journal Article
DNA polymerase clamp loaders and DNA recognition
Bowman, Gregory D., Goedken, Eric R., Kazmirski, Steven L., O’Donnell, Mike, Kuriyan, John
Published in FEBS letters (07.02.2005)
Published in FEBS letters (07.02.2005)
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P2-259 Cancer risk in children with birth defects: a longitudinal, population-based assessment among 2.7 million births
Romitti, P A, Flood, T, Feldkamp, M L, Krikov, S, Puzhankara, S, Goedken, R, Fluchel, M, Little, J, Botto, L D
Published in Journal of epidemiology and community health (1979) (01.08.2011)
Published in Journal of epidemiology and community health (1979) (01.08.2011)
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ACT1 Is Required for Murine IL-23–Induced Psoriasiform Inflammation Potentially Independent of E3 Ligase Activity
Lipovsky, Alex, Slivka, Peter F., Su, Zhi, Wang, Yibing, Paulsboe, Stephanie, Wetter, Joseph, Namovic, Marian T., Gauvin, Donna, Perron, Denise, Gauld, Stephen B., McGaraughty, Steven, Goedken, Eric R.
Published in Journal of investigative dermatology (01.07.2021)
Published in Journal of investigative dermatology (01.07.2021)
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Journal Article
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds
Ramos, Ashley L., Goedken, Eric R., Frank, Kristine E., Argiriadi, Maria A., Bazzaz, Sana, Bian, Zhiguo, Brown, Jesse T. C., Centrella, Paolo A., Chen, Hui-Ju, Disch, Jeremy S., Donner, Pamela L., Duignan, David B., Gikunju, Diana, Greszler, Stephen N., Guié, Marie-Aude, Habeshian, Sevan, Hartl, Hajnalka E., Hein, Christopher D., Hutchins, Charles W., Jetson, Rachael, Keefe, Anthony D., Khan, Hasan, Li, Huan-Qiu, Olszewski, Allison, Ortiz Cardona, Benjamin J., Osuma, Augustine, Panchal, Sanjay C., Phelan, Ryan, Qiu, Wei, Shotwell, J. Brad, Shrestha, Anurupa, Srikumaran, Myron, Su, Zhi, Sun, Chaohong, Upadhyay, Anup K., Wood, Michael D., Wu, Haihong, Zhang, Ruijie, Zhang, Ying, Zhao, Gang, Zhu, Haizhong, Webster, Matthew P.
Published in Journal of medicinal chemistry (25.04.2024)
Published in Journal of medicinal chemistry (25.04.2024)
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Importance of PLD2 in an IL-23 driven psoriasiform dermatitis model and potential link to human psoriasis
Su, Zhi, Slivka, Peter, Paulsboe, Stephanie, Chu, Katherine, Wetter, Joseph B, Namovic, Marian, Perron, Denise, Kannan, Arun, Wan, Qi, Manning, Charlene, Todorovic, Viktor, Smith, Kathleen M, Lipovsky, Alex, Wang, Yibing, Frank, Kristine, McGaraughty, Steve, Loud, Jacqueline, Scott, Victoria E, Honore, Prisca, Goedken, Eric R
Published in Journal of dermatology (01.10.2023)
Published in Journal of dermatology (01.10.2023)
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Journal Article
The Mechanism of ATP-Dependent Primer-Template Recognition by a Clamp Loader Complex
Simonetta, Kyle R., Kazmirski, Steven L., Goedken, Eric R., Cantor, Aaron J., Kelch, Brian A., McNally, Randall, Seyedin, Steven N., Makino, Debora L., O'Donnell, Mike, Kuriyan, John
Published in Cell (15.05.2009)
Published in Cell (15.05.2009)
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Small Molecule and Pooled CRISPR Screens Investigating IL17 Signaling Identify BRD2 as a Novel Contributor to Keratinocyte Inflammatory Responses
Slivka, Peter F, Hsieh, Chen-Lin, Lipovsky, Alex, Pratt, Steven D, Locklear, John, Namovic, Marian T, McDonald, Heath A, Wetter, Joseph, Edelmayer, Rebecca, Hu, Min, Murphy, Erin, Domanus, Marc, Lu, Charles, Duggan, Ryan, King, Jacob, Scott, Victoria E, Donnelly-Roberts, Diana, Slavin, Anthony, Gopalakrishnan, Sujatha, Chung, Namjin, Goedken, Eric R
Published in ACS chemical biology (17.05.2019)
Published in ACS chemical biology (17.05.2019)
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Divalent metal cofactor binding in the kinetic folding trajectory of Escherichia coli ribonuclease HI
GOEDKEN, ERIC R., KECK, JAMES L., BERGER, JAMES M., MARQUSEE, SUSAN
Published in Protein science (01.10.2000)
Published in Protein science (01.10.2000)
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Journal Article
Merits and Pitfalls in the Characterization of Covalent Inhibitors of Bruton’s Tyrosine Kinase
Harris, Christopher M., Foley, Sage E., Goedken, Eric R., Michalak, Mark, Murdock, Sara, Wilson, Noel S.
Published in SLAS discovery (01.12.2018)
Published in SLAS discovery (01.12.2018)
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