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Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities
Rambow, Florian, Marine, Jean-Christophe, Goding, Colin R.
Published in Genes & development (01.10.2019)
Published in Genes & development (01.10.2019)
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Sublethal cytochrome c release generates drug-tolerant persister cells
Kalkavan, Halime, Chen, Mark J., Crawford, Jeremy C., Quarato, Giovanni, Fitzgerald, Patrick, Tait, Stephen W.G., Goding, Colin R., Green, Douglas R.
Published in Cell (01.09.2022)
Published in Cell (01.09.2022)
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A TFEB nuclear export signal integrates amino acid supply and glucose availability
Li, Linxin, Friedrichsen, Hans J., Andrews, Sarah, Picaud, Sarah, Volpon, Laurent, Ngeow, Kaochin, Berridge, Georgina, Fischer, Roman, Borden, Katherine L. B., Filippakopoulos, Panagis, Goding, Colin R.
Published in Nature communications (11.07.2018)
Published in Nature communications (11.07.2018)
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Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma
Müller, Judith, Krijgsman, Oscar, Tsoi, Jennifer, Robert, Lidia, Hugo, Willy, Song, Chunying, Kong, Xiangju, Possik, Patricia A., Cornelissen-Steijger, Paulien D. M., Foppen, Marnix H Geukes, Kemper, Kristel, Goding, Colin R., McDermott, Ultan, Blank, Christian, Haanen, John, Graeber, Thomas G., Ribas, Antoni, Lo, Roger S., Peeper, Daniel S.
Published in Nature communications (15.12.2014)
Published in Nature communications (15.12.2014)
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Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity
Vivas-García, Yurena, Falletta, Paola, Liebing, Jana, Louphrasitthiphol, Pakavarin, Feng, Yongmei, Chauhan, Jagat, Scott, David A., Glodde, Nicole, Chocarro-Calvo, Ana, Bonham, Sarah, Osterman, Andrei L., Fischer, Roman, Ronai, Ze’ev, García-Jiménez, Custodia, Hölzel, Michael, Goding, Colin R.
Published in Molecular cell (02.01.2020)
Published in Molecular cell (02.01.2020)
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MC1R Is a Potent Regulator of PTEN after UV Exposure in Melanocytes
Cao, Juxiang, Wan, Lixin, Hacker, Elke, Dai, Xiangpeng, Lenna, Stefania, Jimenez-Cervantes, Celia, Wang, Yongjun, Leslie, Nick R., Xu, George X., Widlund, Hans R., Ryu, Byungwoo, Alani, Rhoda M., Dutton-Regester, Ken, Goding, Colin R., Hayward, Nicholas K., Wei, Wenyi, Cui, Rutao
Published in Molecular cell (22.08.2013)
Published in Molecular cell (22.08.2013)
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Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy
Zhu, Bo, Tang, Liming, Chen, Shuyang, Yin, Chengqian, Peng, Shiguang, Li, Xin, Liu, Tongzheng, Liu, Wei, Han, Changpeng, Stawski, Lukasz, Xu, Zhi-Xiang, Zhou, Guangbiao, Chen, Xiang, Gao, Xiumei, Goding, Colin R., Xu, Nan, Cui, Rutao, Cao, Peng
Published in Oncogene (01.09.2018)
Published in Oncogene (01.09.2018)
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Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma
Falletta, Paola, Sanchez-del-Campo, Luis, Chauhan, Jagat, Effern, Maike, Kenyon, Amy, Kershaw, Christopher J., Siddaway, Robert, Lisle, Richard, Freter, Rasmus, Daniels, Matthew J., Lu, Xin, Tüting, Thomas, Middleton, Mark, Buffa, Francesca M., Willis, Anne E., Pavitt, Graham, Ronai, Ze'ev A., Sauka-Spengler, Tatjana, Hölzel, Michael, Goding, Colin R.
Published in Genes & development (01.01.2017)
Published in Genes & development (01.01.2017)
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The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor
Coe, Elizabeth A., Tan, Jennifer Y., Shapiro, Michael, Louphrasitthiphol, Pakavarin, Bassett, Andrew R., Marques, Ana C., Goding, Colin R., Vance, Keith W.
Published in PLoS genetics (01.12.2019)
Published in PLoS genetics (01.12.2019)
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Alternate RASSF1 Transcripts Control SRC Activity, E-Cadherin Contacts, and YAP-Mediated Invasion
Vlahov, Nikola, Scrace, Simon, Soto, Manuel Sarmiento, Grawenda, Anna M., Bradley, Leanne, Pankova, Daniela, Papaspyropoulos, Angelos, Yee, Karen S., Buffa, Francesca, Goding, Colin R., Timpson, Paul, Sibson, Nicola, O’Neill, Eric
Published in Current biology (07.12.2015)
Published in Current biology (07.12.2015)
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The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression
Jessen, Christina, Kreß, Julia K. C., Baluapuri, Apoorva, Hufnagel, Anita, Schmitz, Werner, Kneitz, Susanne, Roth, Sabine, Marquardt, André, Appenzeller, Silke, Ade, Carsten P., Glutsch, Valerie, Wobser, Marion, Friedmann-Angeli, José Pedro, Mosteo, Laura, Goding, Colin R., Schilling, Bastian, Geissinger, Eva, Wolf, Elmar, Meierjohann, Svenja
Published in Oncogene (29.10.2020)
Published in Oncogene (29.10.2020)
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Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads
Chen, Shuyang, Han, Changpeng, Miao, Xiao, Li, Xin, Yin, Chengqian, Zou, Junrong, Liu, Min, Li, Shanshan, Stawski, Lukasz, Zhu, Bo, Shi, Qiong, Xu, Zhi-Xiang, Li, Chunying, Goding, Colin R., Zhou, Jun, Cui, Rutao
Published in Nature communications (20.02.2019)
Published in Nature communications (20.02.2019)
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Directed Phenotype Switching as an Effective Antimelanoma Strategy
Sáez-Ayala, Magalí, Montenegro, María F., Sánchez-del-Campo, Luis, Fernández-Pérez, María Piedad, Chazarra, Soledad, Freter, Rasmus, Middleton, Mark, Piñero-Madrona, Antonio, Cabezas-Herrera, Juan, Goding, Colin R., Rodríguez-López, José Neptuno
Published in Cancer cell (08.07.2013)
Published in Cancer cell (08.07.2013)
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Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma
Gonzalez-Meljem, Jose Mario, Haston, Scott, Carreno, Gabriela, Apps, John R., Pozzi, Sara, Stache, Christina, Kaushal, Grace, Virasami, Alex, Panousopoulos, Leonidas, Mousavy-Gharavy, Seyedeh Neda, Guerrero, Ana, Rashid, Mamunur, Jani, Nital, Goding, Colin R., Jacques, Thomas S., Adams, David J., Gil, Jesus, Andoniadou, Cynthia L., Martinez-Barbera, Juan Pedro
Published in Nature communications (28.11.2017)
Published in Nature communications (28.11.2017)
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Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP
Lu, Min, Breyssens, Hilde, Salter, Victoria, Zhong, Shan, Hu, Ying, Baer, Caroline, Ratnayaka, Indrika, Sullivan, Alex, Brown, Nicholas R., Endicott, Jane, Knapp, Stefan, Kessler, Benedikt M., Middleton, Mark R., Siebold, Christian, Jones, E. Yvonne, Sviderskaya, Elena V., Cebon, Jonathan, John, Thomas, Caballero, Otavia L., Goding, Colin R., Lu, Xin
Published in Cancer cell (13.05.2013)
Published in Cancer cell (13.05.2013)
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