The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells
Longo, Pablo G., Laurenti, Luca, Gobessi, Stefania, Sica, Simona, Leone, Giuseppe, Efremov, Dimitar G.
Published in Blood (15.01.2008)
Published in Blood (15.01.2008)
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MAGE-A Tumor Antigens Target p53 Transactivation Function through Histone Deacetylase Recruitment and Confer Resistance to Chemotherapeutic Agents
Monte, Martin, Simonatto, Marta, Peche, Leticia Y., Bublik, Debora R., Gobessi, Stefania, Pierotti, Marco A., Rodolfo, Monica, Schneider, Claudio
Published in Proceedings of the National Academy of Sciences - PNAS (25.07.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (25.07.2006)
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p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape
Patrussi, Laura, Capitani, Nagaja, Ulivieri, Cristina, Manganaro, Noemi, Granai, Massimo, Cattaneo, Francesca, Kabanova, Anna, Mundo, Lucia, Gobessi, Stefania, Frezzato, Federica, Visentin, Andrea, Finetti, Francesca, Pelicci, Pier Giuseppe, D'Elios, Mario M, Trentin, Livio, Semenzato, Gianpietro, Leoncini, Lorenzo, Efremov, Dimitar G, Baldari, Cosima T
Published in Haematologica (Roma) (01.10.2019)
Published in Haematologica (Roma) (01.10.2019)
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A Specific CD44lo CD25lo Subpopulation of Regulatory T Cells Inhibits Anti-Leukemic Immune Response and Promotes the Progression in a Mouse Model of Chronic Lymphocytic Leukemia
Goral, Agnieszka, Firczuk, Malgorzata, Fidyt, Klaudyna, Sledz, Marta, Simoncello, Francesca, Siudakowska, Karolina, Pagano, Giulia, Moussay, Etienne, Paggetti, Jérôme, Nowakowska, Patrycja, Gobessi, Stefania, Barankiewicz, Joanna, Salomon-Perzynski, Aleksander, Benvenuti, Federica, Efremov, Dimitar G, Juszczynski, Przemyslaw, Lech-Maranda, Ewa, Muchowicz, Angelika
Published in Frontiers in immunology (28.02.2022)
Published in Frontiers in immunology (28.02.2022)
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Inhibition of thioredoxin-dependent H2O2 removal sensitizes malignant B-cells to pharmacological ascorbate
Graczyk-Jarzynka, Agnieszka, Goral, Agnieszka, Muchowicz, Angelika, Zagozdzon, Radoslaw, Winiarska, Magdalena, Bajor, Malgorzata, Trzeciecka, Anna, Fidyt, Klaudyna, Krupka, Joanna Alicja, Cyran, Julia, Szczygiel, Kacper, Efremov, Dimitar G., Gobessi, Stefania, Jagielski, Adam, Siudakowska, Karolina, Bobrowicz, Malgorzata, Klopotowska, Marta, Barankiewicz, Joanna, Malenda, Agata, Lech-Maranda, Ewa, Miazek-Zapala, Nina, Skarzynski, Piotr Henryk, Domagala, Antoni, Golab, Jakub, Firczuk, Malgorzata
Published in Redox biology (01.02.2019)
Published in Redox biology (01.02.2019)
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Wiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells
Prete, Francesca, Catucci, Marco, Labrada, Mayrel, Gobessi, Stefania, Castiello, Maria Carmina, Bonomi, Elisa, Aiuti, Alessandro, Vermi, William, Cancrini, Caterina, Metin, Ayse, Hambleton, Sophie, Bredius, Robbert, Notarangelo, Luigi Daniele, van der Burg, Mirjam, Kalinke, Ulrich, Villa, Anna, Benvenuti, Federica
Published in The Journal of experimental medicine (11.02.2013)
Published in The Journal of experimental medicine (11.02.2013)
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FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy
Pyrzynska, Beata, Dwojak, Michal, Zerrouqi, Abdessamad, Morlino, Giulia, Zapala, Piotr, Miazek, Nina, Zagozdzon, Agnieszka, Bojarczuk, Kamil, Bobrowicz, Malgorzata, Siernicka, Marta, Machnicki, Marcin M., Gobessi, Stefania, Barankiewicz, Joanna, Lech-Maranda, Ewa, Efremov, Dimitar G., Juszczynski, Przemyslaw, Calado, Dinis, Golab, Jakub, Winiarska, Magdalena
Published in Oncoimmunology (04.05.2018)
Published in Oncoimmunology (04.05.2018)
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Phosphorylation of the activation loop tyrosines is required for sustained Syk signaling and growth factor-independent B-cell proliferation
Carsetti, Laura, Laurenti, Luca, Gobessi, Stefania, Longo, Pablo G., Leone, Giuseppe, Efremov, Dimitar G.
Published in Cellular signalling (01.07.2009)
Published in Cellular signalling (01.07.2009)
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The Aurora A and B kinases are up-regulated in bone marrow-derived chronic lymphocytic leukemia cells and represent potential therapeutic targets
DE PAULA CARETA, Francisco, GOBESSI, Stefania, ALEXANDRE PANEPUCCI, Rodrigo, BOJNIK, Engin, DE OLIVEIRA, Fabio Morato, MAZZA MATOS, Daniel, FALCAO, Roberto P, LAURENTI, Luca, ZAGO, Marco A, EFREMOV, Dimitar G
Published in Haematologica (Roma) (01.08.2012)
Published in Haematologica (Roma) (01.08.2012)
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BCR signaling inhibitors differ in their ability to overcome Mcl-1–mediated resistance of CLL B cells to ABT-199
Bojarczuk, Kamil, Sasi, Binu K., Gobessi, Stefania, Innocenti, Idanna, Pozzato, Gabriele, Laurenti, Luca, Efremov, Dimitar G.
Published in Blood (23.06.2016)
Published in Blood (23.06.2016)
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Macrophage- and BCR-derived but not TLR-derived signals support the growth of CLL and Richter syndrome murine models in vivo
Martines, Claudio, Chakraborty, Supriya, Vujovikj, Marija, Gobessi, Stefania, Vaisitti, Tiziana, Deaglio, Silvia, Laurenti, Luca, Dimovski, Aleksandar J., Efremov, Dimitar G.
Published in Blood (01.12.2022)
Published in Blood (01.12.2022)
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Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL)
Woyach, Jennifer A., Bojnik, Engin, Ruppert, Amy S., Stefanovski, Matthew R., Goettl, Virginia M., Smucker, Kelly A., Smith, Lisa L., Dubovsky, Jason A., Towns, William H., MacMurray, Jessica, Harrington, Bonnie K., Davis, Melanie E., Gobessi, Stefania, Laurenti, Luca, Chang, Betty Y., Buggy, Joseph J., Efremov, Dimitar G., Byrd, John C., Johnson, Amy J.
Published in Blood (20.02.2014)
Published in Blood (20.02.2014)
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Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT
Negro, Roberto, Gobessi, Stefania, Longo, Pablo G., He, Yantao, Zhang, Zhong-Yin, Laurenti, Luca, Efremov, Dimitar G.
Published in Blood (28.06.2012)
Published in Blood (28.06.2012)
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Hyper-Activation of the Adenosinergic Axis in the Eμ-TCL1 Chronic Lymphocytic Leukemia Mouse Model Offers Therapeutic Opportunities
Vaisitti, Tiziana, Serra, Sara, Bologna, Cinzia, Vitale, Nicoletta, Gobessi, Stefania, Efremov, Dimitar G, Deaglio, Silvia
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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FcμR Triggering Activates BCR Signaling Pathways and Increases Survival of CLL Cells
Gobessi, Stefania, Sasi, Binu K, Pozzato, Gabriele, Innocenti, Idanna, Laurenti, Luca, Efremov, Dimitar G
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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ZAP-70 enhances B-cell–receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells
Gobessi, Stefania, Laurenti, Luca, Longo, Pablo G., Sica, Simona, Leone, Giuseppe, Efremov, Dimitar G.
Published in Blood (01.03.2007)
Published in Blood (01.03.2007)
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Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL
Iacovelli, Stefano, Hug, Eva, Bennardo, Sara, Duehren-von Minden, Marcus, Gobessi, Stefania, Rinaldi, Andrea, Suljagic, Mirza, Bilbao, Daniel, Bolasco, Giulia, Eckl-Dorna, Julia, Niederberger, Verena, Autore, Francesco, Sica, Simona, Laurenti, Luca, Wang, Hongsheng, Cornall, Richard J, Clarke, Stephen H, Croce, Carlo M, Bertoni, Francesco, Jumaa, Hassan, Efremov, Dimitar G
Published in Blood (05.03.2015)
Published in Blood (05.03.2015)
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