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Alzheimer’s Disease Genetics: From the Bench to the Clinic
Karch, Celeste M., Cruchaga, Carlos, Goate, Alison M.
Published in Neuron (Cambridge, Mass.) (02.07.2014)
Published in Neuron (Cambridge, Mass.) (02.07.2014)
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ApoE Cascade Hypothesis in the pathogenesis of Alzheimer’s disease and related dementias
Martens, Yuka A., Zhao, Na, Liu, Chia-Chen, Kanekiyo, Takahisa, Yang, Austin J., Goate, Alison M., Holtzman, David M., Bu, Guojun
Published in Neuron (Cambridge, Mass.) (20.04.2022)
Published in Neuron (Cambridge, Mass.) (20.04.2022)
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Alzheimer's disease: the challenge of the second century
Holtzman, David M, Morris, John C, Goate, Alison M
Published in Science translational medicine (06.04.2011)
Published in Science translational medicine (06.04.2011)
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Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
TCW, Julia, Qian, Lu, Pipalia, Nina H., Chao, Michael J., Liang, Shuang A., Shi, Yang, Jain, Bharat R., Bertelsen, Sarah E., Kapoor, Manav, Marcora, Edoardo, Sikora, Elizabeth, Andrews, Elizabeth J., Martini, Alessandra C., Karch, Celeste M., Head, Elizabeth, Holtzman, David M., Zhang, Bin, Wang, Minghui, Maxfield, Frederick R., Poon, Wayne W., Goate, Alison M.
Published in Cell (23.06.2022)
Published in Cell (23.06.2022)
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Epigenetic regulation of brain region-specific microglia clearance activity
Ayata, Pinar, Badimon, Ana, Strasburger, Hayley J., Duff, Mary Kaye, Montgomery, Sarah E., Loh, Yong-Hwee E., Ebert, Anja, Pimenova, Anna A., Ramirez, Brianna R., Chan, Andrew T., Sullivan, Josefa M., Purushothaman, Immanuel, Scarpa, Joseph R., Goate, Alison M., Busslinger, Meinrad, Shen, Li, Losic, Bojan, Schaefer, Anne
Published in Nature neuroscience (01.08.2018)
Published in Nature neuroscience (01.08.2018)
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Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice
Caballero, Benjamin, Bourdenx, Mathieu, Luengo, Enrique, Diaz, Antonio, Sohn, Peter Dongmin, Chen, Xu, Wang, Chao, Juste, Yves R., Wegmann, Susanne, Patel, Bindi, Young, Zapporah T., Kuo, Szu Yu, Rodriguez-Navarro, Jose Antonio, Shao, Hao, Lopez, Manuela G., Karch, Celeste M., Goate, Alison M., Gestwicki, Jason E., Hyman, Bradley T., Gan, Li, Cuervo, Ana Maria
Published in Nature communications (14.04.2021)
Published in Nature communications (14.04.2021)
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Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes
Novikova, Gloriia, Kapoor, Manav, TCW, Julia, Abud, Edsel M., Efthymiou, Anastasia G., Chen, Steven X., Cheng, Haoxiang, Fullard, John F., Bendl, Jaroslav, Liu, Yiyuan, Roussos, Panos, Björkegren, Johan LM, Liu, Yunlong, Poon, Wayne W., Hao, Ke, Marcora, Edoardo, Goate, Alison M.
Published in Nature communications (12.03.2021)
Published in Nature communications (12.03.2021)
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Coding variants in TREM2 increase risk for Alzheimer's disease
Jin, Sheng Chih, Benitez, Bruno A., Karch, Celeste M., Cooper, Breanna, Skorupa, Tara, Carrell, David, Norton, Joanne B., Hsu, Simon, Harari, Oscar, Cai, Yefei, Bertelsen, Sarah, Goate, Alison M., Cruchaga, Carlos
Published in Human molecular genetics (01.11.2014)
Published in Human molecular genetics (01.11.2014)
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GWAS on family history of Alzheimer’s disease
Marioni, Riccardo E., Harris, Sarah E., Zhang, Qian, McRae, Allan F., Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine R., Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R., Visscher, Peter M.
Published in Translational psychiatry (18.05.2018)
Published in Translational psychiatry (18.05.2018)
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Expression of Novel Alzheimer’s Disease Risk Genes in Control and Alzheimer’s Disease Brains
Karch, Celeste M., Jeng, Amanda T., Nowotny, Petra, Cady, Janet, Cruchaga, Carlos, Goate, Alison M.
Published in PloS one (30.11.2012)
Published in PloS one (30.11.2012)
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A Tale of Two Genes: Microglial Apoe and Trem2
Pimenova, Anna A., Marcora, Edoardo, Goate, Alison M.
Published in Immunity (Cambridge, Mass.) (19.09.2017)
Published in Immunity (Cambridge, Mass.) (19.09.2017)
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ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids
Bowles, Kathryn R., Silva, M. Catarina, Whitney, Kristen, Bertucci, Taylor, Berlind, Joshua E., Lai, Jesse D., Garza, Jacob C., Boles, Nathan C., Mahali, Sidhartha, Strang, Kevin H., Marsh, Jacob A., Chen, Cynthia, Pugh, Derian A., Liu, Yiyuan, Gordon, Ronald E., Goderie, Susan K., Chowdhury, Rebecca, Lotz, Steven, Lane, Keith, Crary, John F., Haggarty, Stephen J., Karch, Celeste M., Ichida, Justin K., Goate, Alison M., Temple, Sally
Published in Cell (19.08.2021)
Published in Cell (19.08.2021)
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An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells
TCW, Julia, Wang, Minghui, Pimenova, Anna A., Bowles, Kathryn R., Hartley, Brigham J., Lacin, Emre, Machlovi, Saima I., Abdelaal, Rawan, Karch, Celeste M., Phatnani, Hemali, Slesinger, Paul A., Zhang, Bin, Goate, Alison M., Brennand, Kristen J.
Published in Stem cell reports (08.08.2017)
Published in Stem cell reports (08.08.2017)
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APOE4 confers transcriptomic and functional alterations to primary mouse microglia
Machlovi, Saima I., Neuner, Sarah M., Hemmer, Brittany M., Khan, Riana, Liu, Yiyuan, Huang, Min, Zhu, Jeffrey D., Castellano, Joseph M., Cai, Dongming, Marcora, Edoardo, Goate, Alison M.
Published in Neurobiology of disease (01.03.2022)
Published in Neurobiology of disease (01.03.2022)
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Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families
Cruchaga, Carlos, Chakraverty, Sumitra, Mayo, Kevin, Vallania, Francesco L. M., Mitra, Robi D., Faber, Kelley, Williamson, Jennifer, Bird, Tom, Diaz-Arrastia, Ramon, Foroud, Tatiana M., Boeve, Bradley F., Graff-Radford, Neill R., St. Jean, Pamela, Lawson, Michael, Ehm, Margaret G., Mayeux, Richard, Goate, Alison M.
Published in PloS one (01.02.2012)
Published in PloS one (01.02.2012)
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