Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody–drug conjugates
Staben, Leanna R., Koenig, Stefan G., Lehar, Sophie M., Vandlen, Richard, Zhang, Donglu, Chuh, Josefa, Yu, Shang-Fan, Ng, Carl, Guo, Jun, Liu, Yanzhou, Fourie-O'Donohue, Aimee, Go, MaryAnn, Linghu, Xin, Segraves, Nathaniel L., Wang, Tao, Chen, Jinhua, Wei, BinQing, Phillips, Gail D. Lewis, Xu, Keyang, Kozak, Katherine R., Mariathasan, Sanjeev, Flygare, John A., Pillow, Thomas H.
Published in Nature chemistry (01.12.2016)
Published in Nature chemistry (01.12.2016)
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Journal Article
Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response
Dela Cruz Chuh, Josefa, Go, MaryAnn, Chen, Yvonne, Guo, Jun, Rafidi, Hanine, Mandikian, Danielle, Sun, Yonglian, Lin, Zhonghua, Schneider, Kellen, Zhang, Pamela, Vij, Rajesh, Sharpnack, Danielle, Chan, Pamela, de la Cruz, Cecile, Sadowsky, Jack, Seshasayee, Dhaya, Koerber, James T, Pillow, Thomas H, Phillips, Gail D, Rowntree, Rebecca K, Boswell, C Andrew, Kozak, Katherine R, Polson, Andrew G, Polakis, Paul, Yu, Shang-Fan, Dragovich, Peter S, Agard, Nicholas J
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
A Novel Anti-CD22 Anthracycline-Based Antibody-Drug Conjugate (ADC) That Overcomes Resistance to Auristatin-Based ADCs
Yu, Shang-Fan, Zheng, Bing, Go, MaryAnn, Lau, Jeff, Spencer, Susan, Raab, Helga, Soriano, Robert, Jhunjhunwala, Suchit, Cohen, Robert, Caruso, Michele, Polakis, Paul, Flygare, John, Polson, Andrew G
Published in Clinical cancer research (15.07.2015)
Published in Clinical cancer research (15.07.2015)
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Journal Article
On Demand Bioorthogonal Switching of an Antibody-Conjugated SPECT Probe to a Cytotoxic Payload: from Imaging to Therapy
Adhikari, Pragya, Li, Guangmin, Go, MaryAnn, Mandikian, Danielle, Rafidi, Hanine, Ng, Carl, Anifa, Sagana, Johnson, Kevin, Bao, Linda, Hernandez Barry, Hilda, Rowntree, Rebecca, Agard, Nicholas, Wu, Cong, Chou, Kang-Jye, Zhang, Donglu, Kozak, Katherine R., Pillow, Thomas H., Lewis, Gail D., Yu, Shang-Fan, Boswell, C. Andrew, Sadowsky, Jack D.
Published in Journal of the American Chemical Society (17.07.2024)
Published in Journal of the American Chemical Society (17.07.2024)
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Journal Article
NKG2D-bispecific enhances NK and CD8+ T cell antitumor immunity
Herault, Aurelie, Mak, Judy, de la Cruz-Chuh, Josefa, Dillon, Michael A., Ellerman, Diego, Go, MaryAnn, Cosino, Ely, Clark, Robyn, Carson, Emily, Yeung, Stacey, Pichery, Melanie, Gador, Mylène, Chiang, Eugene Y., Wu, Jia, Liang, Yuxin, Modrusan, Zora, Gampa, Gautham, Sudhamsu, Jawahar, Kemball, Christopher C., Cheung, Victoria, Nguyen, Thi Thu Thao, Seshasayee, Dhaya, Piskol, Robert, Totpal, Klara, Yu, Shang-Fan, Lee, Genee, Kozak, Katherine R., Spiess, Christoph, Walsh, Kevin B.
Published in Cancer Immunology, Immunotherapy : CII (08.08.2024)
Published in Cancer Immunology, Immunotherapy : CII (08.08.2024)
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Journal Article
Targeting MCL‐1 and BCL‐2 with polatuzumab vedotin and venetoclax overcomes treatment resistance in R/R non‐Hodgkin lymphoma: Results from preclinical models and a Phase Ib study
Lasater, Elisabeth A., Amin, Dhara N., Bannerji, Rajat, Mali, Raghuveer Singh, Barrett, Kathy, Rys, Ryan N., Oeh, Jason, Lin, Eva, Sterne‐Weiler, Tim, Ingalla, Ellen Rei, Go, MaryAnn, Yu, Shang‐Fan, Krem, Maxwell M., Arthur, Chris, Hahn, Uwe, Johnston, Anna, Karur, Vinit, Khan, Nadia, Marlton, Paula, Phillips, Tycel, Gritti, Giuseppe, Seymour, John F., Tani, Monica, Yuen, Sam, Martin, Scott, Chang, Matthew T., Rose, Christopher M., Pham, Victoria C., Polson, Andrew G., Chang, YiMeng, Wever, Claudia, Johnson, Nathalie A., Jiang, Yanwen, Hirata, Jamie, Sampath, Deepak, Musick, Lisa, Flowers, Christopher R., Wertz, Ingrid E.
Published in American journal of hematology (01.03.2023)
Published in American journal of hematology (01.03.2023)
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Journal Article
DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma
Li, Dongwei, Poon, Kirsten Achilles, Yu, Shang-Fan, Dere, Randall, Go, MaryAnn, Lau, Jeffrey, Zheng, Bing, Elkins, Kristi, Danilenko, Dimitry, Kozak, Katherine R, Chan, Pamela, Chuh, Josefa, Shi, Xiaoyan, Nazzal, Denise, Fuh, Franklin, McBride, Jacqueline, Ramakrishnan, Vanitha, de Tute, Ruth, Rawstron, Andy, Jack, Andrew S, Deng, Rong, Chu, Yu-Waye, Dornan, David, Williams, Marna, Ho, William, Ebens, Allen, Prabhu, Saileta, Polson, Andrew G
Published in Molecular cancer therapeutics (01.07.2013)
Published in Molecular cancer therapeutics (01.07.2013)
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Journal Article
FcRL5 as a target of antibody-drug conjugates for the treatment of multiple myeloma
Elkins, Kristi, Zheng, Bing, Go, Maryann, Slaga, Dionysos, Du, Changchun, Scales, Suzie J, Yu, Shang-Fan, McBride, Jacqueline, de Tute, Ruth, Rawstron, Andy, Jack, Andrew S, Ebens, Allen, Polson, Andrew G
Published in Molecular cancer therapeutics (01.10.2012)
Published in Molecular cancer therapeutics (01.10.2012)
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Journal Article
Abstract CT133: Targeting BCL-2 and MCL-1 overcomes treatment resistance in relapsed and refractory non-Hodgkin lymphoma: Pre-clinical rationale and results from an open-label phase 1b study
Amin, Dhara N., Bannerji, Rajat, Mali, Raghuveer Singh, Oeh, Jason, Lin, Eva, Zindal, Anuradha, Go, MaryAnn, Yu, Shang-Fan, Krem, Maxwell, Arthur, Chris, Hahn, Uwe, Johnston, Anna M., Karur, Vinit G., Khan, Nadia, Marlton, Paula, Phillips, Tycel, Gritti, Giuseppe, Seymour, John F., Tani, Monica, Yuen, Sam Yuen, Martin, Scott, Chang, Matthew T., Rose, Christopher M., Pham, Victoria C., Lasater, Elizabeth A., Polson, Andrew G., Chang, YiMeng, Hirata, Jamie, Musick, Lisa, Sampath, Deepak, Flowers, Christopher R., Wertz, Ingrid E.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
ImmunoPET helps predicting the efficacy of antibody-drug conjugates targeting TENB2 and STEAP1
Williams, Simon-Peter, Ogasawara, Annie, Tinianow, Jeff N, Flores, Judith E, Kan, David, Lau, Jeffrey, Go, MaryAnn, Vanderbilt, Alexander N, Gill, Herman S, Miao, Li, Goldsmith, Joshua, Rubinfeld, Bonnee, Mao, Weiguang, Firestein, Ron, Yu, Shang-Fan, Marik, Jan, Terwisscha van Scheltinga, Anton G T
Published in Oncotarget (03.05.2016)
Published in Oncotarget (03.05.2016)
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Journal Article
Abstract 4634: Anthracycline based antibody-drug conjugates (ADCs) for the treatment of non-Hodgkin's lymphoma are effective in cell lines resistant to auristatin based ADCs
Polson, Andrew G., Zheng, Bing, Go, MaryAnn, Lau, Jeffery, Yu, Shang-Fan, Spencer, Susan, Cohen, Robert, Caruso, Michele, Flygare, John, Polakis, Paul
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response
Dela Cruz Chuh, Josefa, Go, MaryAnn, Chen, Yvonne, Guo, Jun, Rafidi, Hanine, Mandikian, Danielle, Sun, Yonglian, Lin, Zhonghua, Schneider, Kellen, Zhang, Pamela, Vij, Rajesh, Sharpnack, Danielle, Chan, Pamela, de la Cruz, Cecile, Sadowsky, Jack, Seshasayee, Dhaya, Koerber, James T., Pillow, Thomas H., Phillips, Gail D., Rowntree, Rebecca K, Boswell, C. Andrew, Kozak, Katherine R., Polson, Andrew G., Polakis, Paul, Yu, Shang-Fan, Dragovich, Peter S., Agard, Nicholas J.
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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