Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer's disease-like pathology
Gnoth, Kathrin, Piechotta, Anke, Kleinschmidt, Martin, Konrath, Sandra, Schenk, Mathias, Taudte, Nadine, Ramsbeck, Daniel, Rieckmann, Vera, Geissler, Stefanie, Eichentopf, Rico, Barendrecht, Susan, Hartlage-Rübsamen, Maike, Demuth, Hans-Ulrich, Roßner, Steffen, Cynis, Holger, Rahfeld, Jens-Ulrich, Schilling, Stephan
Published in Alzheimer's research & therapy (14.11.2020)
Published in Alzheimer's research & therapy (14.11.2020)
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Journal Article
Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice
Gnoth, Kathrin, Geissler, Stefanie, Feldhaus, Julia, Taudte, Nadine, Ilse, Victoria, Zürner, Sebastian, Greiser, Sebastian, Braumann, Ulf-Dietrich, Rahfeld, Jens-Ulrich, Cynis, Holger, Schilling, Stephan
Published in Biomolecules (Basel, Switzerland) (04.03.2022)
Published in Biomolecules (Basel, Switzerland) (04.03.2022)
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Journal Article
Combinational therapy, concomitantly targeting post‐translational modified Aβ peptides and CD33, leads to an add‐on effect in passive immunotherapy
Gnoth, Kathrin, Geissler, Stefanie, Ilse, Victoria, Rahfeld, Jens‐Ulrich, Cynis, Holger, Schilling, Stephan
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Journal Article
Exploring Combination Therapies in AD: Additive Effects of the QPCT Inhibitor Varoglutamstat and Aducanumab on Aβ Pathology and Biomarkers In Vivo
Hoffmann, Torsten, Schenk, Mathias, Gnoth, Kathrin, Ilse, Victoria, Brunner, Daniela, Rahfeld, Jens‐Ulrich, Schilling, Stephan, Schaeffer, Michael
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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Journal Article
Seeding, maturation and propagation of amyloid β-peptide aggregates in Alzheimer's disease
Li, Xiaohang, Ospitalieri, Simona, Robberechts, Tessa, Hofmann, Linda, Schmid, Christina, Rijal Upadhaya, Ajeet, Koper, Marta J, von Arnim, Christine A F, Kumar, Sathish, Willem, Michael, Gnoth, Kathrin, Ramakers, Meine, Schymkowitz, Joost, Rousseau, Frederic, Walter, Jochen, Ronisz, Alicja, Balakrishnan, Karthikeyan, Thal, Dietmar Rudolf
Published in Brain (London, England : 1878) (21.10.2022)
Published in Brain (London, England : 1878) (21.10.2022)
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Journal Article
Structural and functional analyses of pyroglutamate-amyloid-β-specific antibodies as a basis for Alzheimer immunotherapy
Piechotta, Anke, Parthier, Christoph, Kleinschmidt, Martin, Gnoth, Kathrin, Pillot, Thierry, Lues, Inge, Demuth, Hans-Ulrich, Schilling, Stephan, Rahfeld, Jens-Ulrich, Stubbs, Milton T.
Published in The Journal of biological chemistry (28.07.2017)
Published in The Journal of biological chemistry (28.07.2017)
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Journal Article
TARGETING ISOASPARTATE-MODIFIED Aβ: A DIFFERENTIAL APPROACH OF PASSIVE IMMUNOTHERAPY
Rahfeld, Jens-Ulrich, Piechotta, Anke, Gnoth, Kathrin, Rossner, Steffen, Nykiel, Vera, Cynis, Holger, Demuth, Hans-Ulrich, Schilling, Stephan
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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Journal Article
P2‐056: TARGETING ISOASPARTATE‐MODIFIED Aβ: A DIFFERENTIAL APPROACH OF PASSIVE IMMUNOTHERAPY
Rahfeld, Jens-Ulrich, Piechotta, Anke, Gnoth, Kathrin, Rossner, Steffen, Nykiel, Vera, Cynis, Holger, Demuth, Hans-Ulrich, Schilling, Stephan
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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Journal Article
Targeting isoaspartate-modified A[beta] rescues behavioral deficits in transgenic mice with Alzheimer's disease-like pathology
Rossner, Steffen, Schilling, Stephan, Konrath, Sandra, Hartlage-Rübsamen, Maike, Geissler, Stefanie, Schenk, Mathias, Barendrecht, Susan, Cynis, Holger, Ramsbeck, Daniel, Taudte, Nadine, Demuth, Hans-Ulrich, Rieckmann, Vera, Rahfeld, Jens-Ulrich, Gnoth, Kathrin, Eichentopf, Rico, Piechotta, Anke, Kleinschmidt, Martin
Published in Alzheimer's research & therapy (14.11.2020)
Published in Alzheimer's research & therapy (14.11.2020)
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Journal Article
Anti-isoAsp7 amyloid β (Aβ) antibodies and uses thereof
Piechotta, Anke, Demuth, Hans-Ulrich, Schilling, Stephan, Rahfeld, Jens-Ulrich, Cynis, Holger, Gnoth, Kathrin
Year of Publication 18.07.2023
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Year of Publication 18.07.2023
Patent
ANTI- ISOASP7 AMYLOID ß (Aß) ANTIBODIES AND USES THEREOF
GNOTH, Kathrin, RAHFELD, Jens-Ulrich, DEMUTH, Hans-Ulrich, CYNIS, Holger, PIECHOTTA, Anke, SCHILLING, Stephan
Year of Publication 20.08.2020
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Year of Publication 20.08.2020
Patent
ANTI- ISOASP7 AMYLOID beta (Abeta) ANTIBODIES AND USES THEREOF
GNOTH, Kathrin, RAHFELD, Jens-Ulrich, DEMUTH, Hans-Ulrich, CYNIS, Holger, PIECHOTTA, Anke, SCHILLING, Stephan
Year of Publication 27.05.2020
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Year of Publication 27.05.2020
Patent
ANTI- ISOASP7 AMYLOID β (Aβ) ANTIBODIES AND USES THEREOF
GNOTH, Kathrin, RAHFELD, Jens-Ulrich, DEMUTH, Hans-Ulrich, CYNIS, Holger, PIECHOTTA, Anke, SCHILLING, Stephan
Year of Publication 24.01.2019
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Year of Publication 24.01.2019
Patent
DIAGNOSTIC ANTIBODY ASSAY
GNOTH, Kathrin, RAHFELD, Jens-Ulrich, KLEINSCHMIDT, Martin, DEMUTH, Hans-Ulrich, REISENAUER-SCHAUPP, Anita, SCHILLING, Stefan, KAMPFER, Sonja
Year of Publication 27.06.2018
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Year of Publication 27.06.2018
Patent
DIAGNOSTIC ANTIBODY ASSAY
GNOTH, Kathrin, RAHFELD, Jens-Ulrich, KLEINSCHMIDT, Martin, DEMUTH, Hans-Ulrich, REISENAUER-SCHAUPP, Anita, SCHILLING, Stefan, KAMPFER, Sonja
Year of Publication 27.06.2018
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Year of Publication 27.06.2018
Patent
Uses of antibodies directed against amyloid-β
Kampfer Sonja, Rahfeld Jens-Ulrich, Kleinschmidt Martin, Gnoth Kathrin, Reisenauer-Schaupp Anita, Schilling Stephan, Demuth Hans-Ulrich
Year of Publication 13.06.2017
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Year of Publication 13.06.2017
Patent