Positive allosteric modulation of GABAA receptors by a novel antiepileptic drug cenobamate
Sharma, Ramesh, Nakamura, Michiko, Neupane, Chiranjivi, Jeon, Byeong Hwa, Shin, Hyewon, Melnick, Susan M., Glenn, Kelli J., Jang, Il-Sung, Park, Jin Bong
Published in European journal of pharmacology (15.07.2020)
Published in European journal of pharmacology (15.07.2020)
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Discovery of RG7388, a Potent and Selective p53–MDM2 Inhibitor in Clinical Development
Ding, Qingjie, Zhang, Zhuming, Liu, Jin-Jun, Jiang, Nan, Zhang, Jing, Ross, Tina M, Chu, Xin-Jie, Bartkovitz, David, Podlaski, Frank, Janson, Cheryl, Tovar, Christian, Filipovic, Zoran M, Higgins, Brian, Glenn, Kelli, Packman, Kathryn, Vassilev, Lyubomir T, Graves, Bradford
Published in Journal of medicinal chemistry (25.07.2013)
Published in Journal of medicinal chemistry (25.07.2013)
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Effect of cenobamate on the single‐dose pharmacokinetics of multiple cytochrome P450 probes using a cocktail approach in healthy subjects
Greene, Stephen A., Kwak, Charles, Kamin, Marc, Vernillet, Laurent, Glenn, Kelli J., Gabriel, Lana, Kim, Hong Wook
Published in Clinical and translational science (01.04.2022)
Published in Clinical and translational science (01.04.2022)
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Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development
Vu, Binh, Wovkulich, Peter, Pizzolato, Giacomo, Lovey, Allen, Ding, Qingjie, Jiang, Nan, Liu, Jin-Jun, Zhao, Chunlin, Glenn, Kelli, Wen, Yang, Tovar, Christian, Packman, Kathryn, Vassilev, Lyubomir, Graves, Bradford
Published in ACS medicinal chemistry letters (09.05.2013)
Published in ACS medicinal chemistry letters (09.05.2013)
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Effect of esomeprazole, a proton pump inhibitor on the pharmacokinetics of sonidegib in healthy volunteers
Zhou, Jocelyn, Quinlan, Michelle, Glenn, Kelli, Boss, Hildegard, Picard, Franck, Castro, Henry, Sellami, Dalila
Published in British journal of clinical pharmacology (01.10.2016)
Published in British journal of clinical pharmacology (01.10.2016)
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Pyrido[2,3-d]pyrimidines: Discovery and preliminary SAR of a novel series of DYRK1B and DYRK1A inhibitors
Anderson, Kevin, Chen, Yi, Chen, Zhi, Dominique, Romyr, Glenn, Kelli, He, Yang, Janson, Cheryl, Luk, Kin-Chun, Lukacs, Christine, Polonskaia, Ann, Qiao, Qi, Railkar, Aruna, Rossman, Pamela, Sun, Hongmao, Xiang, Qing, Vilenchik, Masha, Wovkulich, Peter, Zhang, Xiaolei
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
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Lapatinib Plasma and Tumor Concentrations and Effects on HER Receptor Phosphorylation in Tumor
Spector, Neil L, Robertson, Faith C, Bacus, Sarah, Blackwell, Kimberly, Smith, Deborah A, Glenn, Kelli, Cartee, Leanne, Harris, Jennifer, Kimbrough, Carie L, Gittelman, Mark, Avisar, Eli, Beitsch, Peter, Koch, Kevin M
Published in PloS one (16.11.2015)
Published in PloS one (16.11.2015)
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Discovery of Potent and Orally Active p53-MDM2 Inhibitors RO5353 and RO2468 for Potential Clinical Development
Zhang, Zhuming, Chu, Xin-Jie, Liu, Jin-Jun, Ding, Qingjie, Zhang, Jing, Bartkovitz, David, Jiang, Nan, Karnachi, Prabha, So, Sung-Sau, Tovar, Christian, Filipovic, Zoran M, Higgins, Brian, Glenn, Kelli, Packman, Kathryn, Vassilev, Lyubomir, Graves, Bradford
Published in ACS medicinal chemistry letters (13.02.2014)
Published in ACS medicinal chemistry letters (13.02.2014)
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Investigating the effect of autoinduction in cynomolgus monkeys of a novel anticancer MDM2 antagonist, idasanutlin, and relevance to humans
Glenn, Kelli J., Yu, Li J., Reddy, Micaela B., Fretland, Adrian J., Parrott, Neil, Hussain, Sazzad, Palacios, Mary, Vazvaei, Faye, Zhi, Jianguo, Tuerck, Dietrich
Published in Xenobiotica (02.08.2016)
Published in Xenobiotica (02.08.2016)
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P154 - Absorption, distribution, metabolism, and excretion of the novel antiepileptic drug cenobamate: mass balance following oral administration in healthy male subjects
Glenn, Kelli J., Greene, Stephen, Kim, Hong-Wook, Melnick, Susan M., Vernillet, Laurent
Published in Drug metabolism and pharmacokinetics (2020)
Published in Drug metabolism and pharmacokinetics (2020)
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Mass Balance, Metabolism, and Excretion of Cenobamate, a New Antiepileptic Drug, After a Single Oral Administration in Healthy Male Subjects
Vernillet, Laurent, Greene, Stephen A., Kim, Hong Wook, Melnick, Susan M., Glenn, Kelli
Published in European journal of drug metabolism and pharmacokinetics (01.08.2020)
Published in European journal of drug metabolism and pharmacokinetics (01.08.2020)
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Activation of p53 by the MDM2 inhibitor RG7112 impairs thrombopoiesis
Iancu-Rubin, Camelia, Mosoyan, Goar, Glenn, Kelli, Gordon, Ronald E, Nichols, Gwen L, Hoffman, Ronald
Published in Experimental hematology (01.02.2014)
Published in Experimental hematology (01.02.2014)
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Preclinical Optimization of MDM2 Antagonist Scheduling for Cancer Treatment by Using a Model-Based Approach
HIGGINS, Brian, GLENN, Kelli, GARRIDO, Rosario, LINN, Michael, MEILLE, Christophe, HEIMBROOK, David, VASSILEV, Lyubomir, PACKMAN, Kathryn, WALZ, Antje, TOVAR, Christian, FILIPOVIC, Zoran, HUSSAIN, Sazzad, LEE, Edmund, KOLINSKY, Kenneth, TANNU, Shahid, ADAMES, Violeta
Published in Clinical cancer research (15.07.2014)
Published in Clinical cancer research (15.07.2014)
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Preclinical Profile of a Potent γ-Secretase Inhibitor Targeting Notch Signaling with In vivo Efficacy and Pharmacodynamic Properties
LUISTRO, Leopoldo, WEI HE, LINN, Michael, FLOHR, Alexander, JAKOB-RØTNE, Roland, JACOBSEN, Helmut, GLENN, Kelli, HEIMBROOK, David, BOYLAN, John F, SMITH, Melissa, PACKMAN, Kathryn, VILENCHIK, Maria, CARVAJAL, Daisy, ROBERTS, John, CAI, James, BERKOFSKY-FESSLER, Windy, HILTON, Holly
Published in Cancer research (Chicago, Ill.) (01.10.2009)
Published in Cancer research (Chicago, Ill.) (01.10.2009)
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Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy
Zhang, Zhuming, Ding, Qingjie, Liu, Jin-Jun, Zhang, Jing, Jiang, Nan, Chu, Xin-Jie, Bartkovitz, David, Luk, Kin-Chun, Janson, Cheryl, Tovar, Christian, Filipovic, Zoran M., Higgins, Brian, Glenn, Kelli, Packman, Kathryn, Vassilev, Lyubomir T., Graves, Bradford
Published in Bioorganic & medicinal chemistry (01.08.2014)
Published in Bioorganic & medicinal chemistry (01.08.2014)
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description of the Southern Rural Access Program's practice management strategies
Adams, G.L, Holloman, C.E, Nye, J.M, Salain, R, Glenn, K.G, Harrison, S, Patterson, M.M
Published in The Journal of rural health (01.01.2003)
Published in The Journal of rural health (01.01.2003)
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