Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
Palsson-McDermott, Eva M., Curtis, Anne M., Goel, Gautam, Lauterbach, Mario A.R., Sheedy, Frederick J., Gleeson, Laura E., van den Bosch, Mirjam W.M., Quinn, Susan R., Domingo-Fernandez, Raquel, Johnston, Daniel G.W., Jiang, Jian-kang, Israelsen, William J., Keane, Joseph, Thomas, Craig, Clish, Clary, Vander Heiden, Matthew, Xavier, Ramnik J., O’Neill, Luke A.J.
Published in Cell metabolism (06.01.2015)
Published in Cell metabolism (06.01.2015)
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Journal Article
Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21
Hackett, Emer E., Charles-Messance, Hugo, O’Leary, Seónadh M., Gleeson, Laura E., Muñoz-Wolf, Natalia, Case, Sarah, Wedderburn, Anna, Johnston, Daniel G.W., Williams, Michelle A., Smyth, Alicia, Ouimet, Mireille, Moore, Kathryn J., Lavelle, Ed C., Corr, Sinéad C., Gordon, Stephen V., Keane, Joseph, Sheedy, Frederick J.
Published in Cell reports (Cambridge) (07.01.2020)
Published in Cell reports (Cambridge) (07.01.2020)
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Journal Article
Cigarette smoking impairs human pulmonary immunity to Mycobacterium tuberculosis
O'Leary, Seónadh M, Coleman, Michelle M, Chew, Wui Mei, Morrow, Colette, McLaughlin, Anne Marie, Gleeson, Laura E, O'Sullivan, Mary P, Keane, Joseph
Published in American journal of respiratory and critical care medicine (15.12.2014)
Published in American journal of respiratory and critical care medicine (15.12.2014)
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Journal Article
The tuberculous pleural effusion
McNally, Emma, Ross, Clare, Gleeson, Laura E
Published in Breathe (Lausanne, Switzerland) (01.12.2023)
Published in Breathe (Lausanne, Switzerland) (01.12.2023)
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Journal Article
Sarcoidosis following COVID infection: A case series
Smith, David J. F., Meghji, Jamilah, Moonim, Mufaddal, Ross, Clare, Viola, Patrizia, Wickremasinghe, Melissa, Gleeson, Laura E.
Published in Respirology case reports (01.11.2023)
Published in Respirology case reports (01.11.2023)
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Journal Article
A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling
Ní Cheallaigh, Clíona, Sheedy, Frederick J., Harris, James, Muñoz-Wolf, Natalia, Lee, Jinhee, West, Kim, McDermott, Eva Palsson, Smyth, Alicia, Gleeson, Laura E., Coleman, Michelle, Martinez, Nuria, Hearnden, Claire H.A., Tynan, Graham A., Carroll, Elizabeth C., Jones, Sarah A., Corr, Sinéad C., Bernard, Nicholas J., Hughes, Mark M., Corcoran, Sarah E., O’Sullivan, Mary, Fallon, Ciara M., Kornfeld, Hardy, Golenbock, Douglas, Gordon, Stephen V., O’Neill, Luke A.J., Lavelle, Ed C., Keane, Joseph
Published in Immunity (Cambridge, Mass.) (16.02.2016)
Published in Immunity (Cambridge, Mass.) (16.02.2016)
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Journal Article
Epigenetic induction of CD1d expression primes lung cancer cells for killing by invariant natural killer T cells
Dockry, Éilis, O'Leary, Seónadh, Gleeson, Laura E., Lyons, Judith, Keane, Joseph, Gray, Steven G., Doherty, Derek G.
Published in Oncoimmunology (03.06.2018)
Published in Oncoimmunology (03.06.2018)
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Journal Article
Obesity, COVID-19 and innate immunometabolism
Gleeson, Laura E., Roche, Helen M., Sheedy, Frederick J.
Published in British Journal of Nutrition (28.03.2021)
Published in British Journal of Nutrition (28.03.2021)
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Journal Article
Cutting Edge: Mycobacterium tuberculosis Induces Aerobic Glycolysis in Human Alveolar Macrophages That Is Required for Control of Intracellular Bacillary Replication
Gleeson, Laura E, Sheedy, Frederick J, Palsson-McDermott, Eva M, Triglia, Denise, O'Leary, Seonadh M, O'Sullivan, Mary P, O'Neill, Luke A J, Keane, Joseph
Published in The Journal of immunology (1950) (15.03.2016)
Published in The Journal of immunology (1950) (15.03.2016)
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Journal Article
Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
Palsson-McDermott, Eva M., Curtis, Anne M., Goel, Gautam, Lauterbach, Mario A.R., Sheedy, Frederick J., Gleeson, Laura E., van den Bosch, Mirjam W.M., Quinn, Susan R., Domingo-Fernandez, Raquel, Johnston, Daniel G.W., Jiang, Jian-kang, Israelsen, William J., Keane, Joseph, Thomas, Craig, Clish, Clary, Vander Heiden, Matthew, Xavier, Ramnik J., O’Neill, Luke A.J.
Published in Cell metabolism (03.02.2015)
Published in Cell metabolism (03.02.2015)
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Journal Article
Cigarette Smoking Impairs the Bioenergetic Immune Response to Mycobacterium tuberculosis Infection
Gleeson, Laura E, O'Leary, Seonadh M, Ryan, Daniel, McLaughlin, Anne Marie, Sheedy, Frederick J, Keane, Joseph
Published in American journal of respiratory cell and molecular biology (01.11.2018)
Published in American journal of respiratory cell and molecular biology (01.11.2018)
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Journal Article
Sharpening nature's tools for efficient tuberculosis control: A review of the potential role and development of host-directed therapies and strategies for targeted respiratory delivery
O'Connor, Gemma, Gleeson, Laura E., Fagan-Murphy, Aidan, Cryan, Sally-Ann, O'Sullivan, Mary P., Keane, Joseph
Published in Advanced drug delivery reviews (01.07.2016)
Published in Advanced drug delivery reviews (01.07.2016)
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Journal Article
Predicting Patient Outcome in the Evolving Field of Malignant Pleural Effusion
Gleeson, Laura E, Gary Lee, Y C
Published in Journal of bronchology & interventional pulmonology (01.01.2020)
Published in Journal of bronchology & interventional pulmonology (01.01.2020)
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Journal Article
Delayed Tuberculosis Paradoxical Reaction Associated with TNF Inhibitors
Roche, Suzanne M., Ottewill, Ciara, Mulpeter, Rachel, Brown, Kevin, Grant, Conor, Fraughen, Daniel D., Dolan, Lorraine, Gleeson, Laura E, McLaughlin, Anne Marie, Keane, Joseph
Published in American journal of respiratory and critical care medicine (12.08.2024)
Published in American journal of respiratory and critical care medicine (12.08.2024)
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