PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
Lin, David Yin-wei, Tanaka, Yoshimasa, Iwasaki, Masashi, Gittis, Apostolos G, Su, Hua-Poo, Mikami, Bunzo, Okazaki, Taku, Honjo, Tasuku, Minato, Nagahiro, Garboczi, David N
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2008)
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Journal Article
ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals
Martin-Martin, Ines, Paige, Andrew, Valenzuela Leon, Paola Carolina, Gittis, Apostolos G., Kern, Olivia, Bonilla, Brian, Chagas, Andrezza Campos, Ganesan, Sundar, Smith, Leticia Barion, Garboczi, David N., Calvo, Eric
Published in Nature communications (09.06.2020)
Published in Nature communications (09.06.2020)
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Journal Article
Mosquito salivary apyrase regulates blood meal hemostasis and facilitates malaria parasite transmission
Pala, Zarna Rajeshkumar, Alves e Silva, Thiago Luiz, Minai, Mahnaz, Crews, Benjamin, Patino-Martinez, Eduardo, Carmona-Rivera, Carmelo, Valenzuela Leon, Paola Carolina, Martin-Martin, Ines, Flores-Garcia, Yevel, Cachau, Raul E., Muslinkina, Liya, Gittis, Apostolos G., Srivastava, Naman, Garboczi, David N., Alves, Derron A., Kaplan, Mariana J., Fischer, Elizabeth, Calvo, Eric, Vega-Rodriguez, Joel
Published in Nature communications (18.09.2024)
Published in Nature communications (18.09.2024)
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Journal Article
Aedes aegypti Piwi4 Structural Features Are Necessary for RNA Binding and Nuclear Localization
Williams, Adeline E, Shrivastava, Gaurav, Gittis, Apostolos G, Ganesan, Sundar, Martin-Martin, Ines, Valenzuela Leon, Paola Carolina, Olson, Ken E, Calvo, Eric
Published in International journal of molecular sciences (25.11.2021)
Published in International journal of molecular sciences (25.11.2021)
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Journal Article
High Apparent Dielectric Constant Inside a Protein Reflects Structural Reorganization Coupled to the Ionization of an Internal Asp
Karp, Daniel A., Gittis, Apostolos G., Stahley, Mary R., Fitch, Carolyn A., Stites, Wesley E., García-Moreno E., Bertrand
Published in Biophysical journal (15.03.2007)
Published in Biophysical journal (15.03.2007)
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Journal Article
Hfqs in Bacillus anthracis: Role of protein sequence variation in the structure and function of proteins in the Hfq family
Vrentas, Catherine, Ghirlando, Rodolfo, Keefer, Andrea, Hu, Zonglin, Tomczak, Aurelie, Gittis, Apostolos G., Murthi, Athulaprabha, Garboczi, David N., Gottesman, Susan, Leppla, Stephen H.
Published in Protein science (01.11.2015)
Published in Protein science (01.11.2015)
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Journal Article
Structure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins
Singh, Kavita, Burkhardt, Martin, Nakuchima, Sofia, Herrera, Raul, Muratova, Olga, Gittis, Apostolos G., Kelnhofer, Emily, Reiter, Karine, Smelkinson, Margery, Veltri, Daniel, Swihart, Bruce J., Shimp, Richard, Nguyen, Vu, Zhang, Baoshan, MacDonald, Nicholas J., Duffy, Patrick E., Garboczi, David N., Narum, David L.
Published in Communications biology (24.07.2020)
Published in Communications biology (24.07.2020)
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Journal Article
The Structure of the Poxvirus A33 Protein Reveals a Dimer of Unique C-Type Lectin-Like Domains
SU, Hua-Poo, SINGH, Kavita, GITTIS, Apostolos G, GARBOCZI, David N
Published in Journal of Virology (01.03.2010)
Published in Journal of Virology (01.03.2010)
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Journal Article
Structural and immunological differences in Plasmodium falciparum sexual stage transmission-blocking vaccines comprised of Pfs25-EPA nanoparticles
MacDonald, Nicholas J., Singh, Kavita, Reiter, Karine, Nguyen, Vu, Shimp, Richard, Gittis, Apostolos G., Chen, Beth, Burkhardt, Martin, Zhang, Baoshan, Wang, Zhixiong, Herrera, Raul, Moler, Mackenzie, Lee, Duck-Yeon, Orr-Gonzalez, Sachy, Herrod, Jessica, Lambert, Lynn E., Rausch, Kelly M., Muratova, Olga, Jones, David S., Wu, Yimin, Jin, Albert J., Garboczi, David N., Duffy, Patrick E., Narum, David L.
Published in npj vaccines (15.04.2023)
Published in npj vaccines (15.04.2023)
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Journal Article
The structures of two salivary proteins from the West Nile vector Culex quinquefasciatus reveal a beta-trefoil fold with putative sugar binding properties
Kern, Olivia, Valenzuela Leon, Paola Carolina, Gittis, Apostolos G., Bonilla, Brian, Cruz, Phillip, Chagas, Andrezza Campos, Ganesan, Sundar, Ribeiro, Jose M.C., Garboczi, David N., Martin-Martin, Ines, Calvo, Eric
Published in Current research in structural biology (01.01.2021)
Published in Current research in structural biology (01.01.2021)
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Journal Article
The cysteine-rich interdomain region from the highly variable plasmodium falciparum erythrocyte membrane protein-1 exhibits a conserved structure
Klein, Michael M, Gittis, Apostolos G, Su, Hua-Poo, Makobongo, Morris O, Moore, Jaime M, Singh, Sanjay, Miller, Louis H, Garboczi, David N
Published in PLoS pathogens (05.09.2008)
Published in PLoS pathogens (05.09.2008)
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Journal Article
High Apparent Dielectric Constants in the Interior of a Protein Reflect Water Penetration
Dwyer, John J., Gittis, Apostolos G., Karp, Daniel A., Lattman, Eaton E., Spencer, Daniel S., Stites, Wesley E., García-Moreno E., Bertrand
Published in Biophysical journal (01.09.2000)
Published in Biophysical journal (01.09.2000)
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Journal Article
A Compact RNA Tertiary Structure Contains a Buried Backbone–K + Complex
Conn, Graeme L, Gittis, Apostolos G, Lattman, Eaton E, Misra, Vinod K, Draper, David E
Published in Journal of molecular biology (10.05.2002)
Published in Journal of molecular biology (10.05.2002)
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Journal Article
Kinetics and Thermodynamics of DbpA Protein’s C‑Terminal Domain Interaction with RNA
López de Victoria, Aliana, Moore, Anthony F. T, Gittis, Apostolos G, Koculi, Eda
Published in ACS omega (30.11.2017)
Published in ACS omega (30.11.2017)
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Journal Article
Structural and functional comparisons of salivary α-glucosidases from the mosquito vectors Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus
Williams, Adeline E., Gittis, Apostolos G., Botello, Karina, Cruz, Phillip, Martin-Martin, Ines, Valenzuela Leon, Paola Carolina, Sumner, Benjamin, Bonilla, Brian, Calvo, Eric
Published in Insect biochemistry and molecular biology (01.04.2024)
Published in Insect biochemistry and molecular biology (01.04.2024)
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Journal Article
Structure-guided design of VAR2CSA-based immunogens and a cocktail strategy for a placental malaria vaccine
Ma, Rui, Salinas, Nichole D, Orr-Gonzalez, Sachy, Richardson, Brandi, Ouahes, Tarik, Torano, Holly, Jenkins, Bethany J, Dickey, Thayne H, Neal, Jillian, Duan, Junhui, Morrison, Robert D, Gittis, Apostolos G, Doritchamou, Justin Y A, Zaidi, Irfan, Lambert, Lynn E, Duffy, Patrick E, Tolia, Niraj H
Published in PLoS pathogens (04.03.2024)
Published in PLoS pathogens (04.03.2024)
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Journal Article
The Vaccinia Virus H3 Envelope Protein, a Major Target of Neutralizing Antibodies, Exhibits a Glycosyltransferase Fold and Binds UDP-Glucose
Singh, Kavita, Gittis, Apostolos G, Gitti, Rossitza K, Ostazeski, Stanley A, Su, Hua-Poo, Garboczi, David N
Published in Journal of virology (15.05.2016)
Published in Journal of virology (15.05.2016)
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Journal Article