The PPAR α/γ Agonist Saroglitazar Improves Insulin Resistance and Steatohepatitis in a Diet Induced Animal Model of Nonalcoholic Fatty Liver Disease
Kumar, Divya P., Caffrey, Rebecca, Marioneaux, Jonathon, Santhekadur, Prasanna K., Bhat, Madhavi, Alonso, Cristina, Koduru, Srinivas V., Philip, Binu, Jain, Mukul R., Giri, Suresh R., Bedossa, Pierre, Sanyal, Arun J.
Published in Scientific reports (09.06.2020)
Published in Scientific reports (09.06.2020)
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Saroglitazar suppresses the hepatocellular carcinoma induced by intraperitoneal injection of diethylnitrosamine in C57BL/6 mice fed on choline deficient, l-amino acid- defined, high-fat diet
Giri, Suresh R, Bhoi, Bibhuti, Trivedi, Chitrang, Rath, Akshyaya, Rathod, Rohan, Sharma, Anish, Ranvir, Ramchandra, Kadam, Shekhar, Ingale, Kailash, Patel, Hiren, Nyska, Abraham, Jain, Mukul R
Published in BMC cancer (17.01.2023)
Published in BMC cancer (17.01.2023)
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Dual PPARα/γ agonist saroglitazar improves liver histopathology and biochemistry in experimental NASH models
Jain, Mukul R., Giri, Suresh R., Bhoi, Bibhuti, Trivedi, Chitrang, Rath, Akshyaya, Rathod, Rohan, Ranvir, Ramchandra, Kadam, Shekhar, Patel, Hiren, Swain, Prabodha, Roy, Sib Sankar, Das, Nabanita, Karmakar, Eshani, Wahli, Walter, Patel, Pankaj R.
Published in Liver international (01.06.2018)
Published in Liver international (01.06.2018)
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Controllable fabrication of Au-nanoprotrusion arrays as a platform for the materials design and characterization
Lin, Wei Ming, Yoshida, Takumi, Suresh, Giri, Pradeepkumar Gupta, Vikaskumar, Ozeki, Shinsuke, Oyama, Kento, Akiyama, Tatsuya, Yaakob, Yazid, Asaka, Toru, Yong, Yang, Miyazaki, Hidetoshi, Sonoyama, Noriyuki, Tanemura, Masaki
Published in Applied surface science (15.03.2023)
Published in Applied surface science (15.03.2023)
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Unraveling the Potential Role of Tecomella undulata in Experimental NASH
Srinivas, Akshatha N, Suresh, Diwakar, Suvarna, Deepak, Pathak, Pankaj, Giri, Suresh, Suman, Satish, Suchitha, Chidambaram, Saravana Babu, Kumar, Divya P
Published in International journal of molecular sciences (07.02.2023)
Published in International journal of molecular sciences (07.02.2023)
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Journal Article
Saroglitazar, a novel PPARα/γ agonist with predominant PPARα activity, shows lipid‐lowering and insulin‐sensitizing effects in preclinical models
Jain, Mukul R., Giri, Suresh R., Trivedi, Chitrang, Bhoi, Bibhuti, Rath, Akshyaya, Vanage, Geeta, Vyas, Purvi, Ranvir, Ramchandra, Patel, Pankaj R.
Published in Pharmacology research & perspectives (01.06.2015)
Published in Pharmacology research & perspectives (01.06.2015)
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ZRC3308 Monoclonal Antibody Cocktail Shows Protective Efficacy in Syrian Hamsters against SARS-CoV-2 Infection
Yadav, Pragya D, Mendiratta, Sanjeev Kumar, Mohandas, Sreelekshmy, Singh, Arun K, Abraham, Priya, Shete, Anita, Bandyopadhyay, Sanjay, Kumar, Sanjay, Parikh, Aashini, Kalita, Pankaj, Sharma, Vibhuti, Pandya, Hardik, Patel, Chirag G, Patel, Mihir, Soni, Swagat, Giri, Suresh, Jain, Mukul
Published in Viruses (03.12.2021)
Published in Viruses (03.12.2021)
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Discovery of a Potent and Orally Efficacious TGR5 Receptor Agonist
Agarwal, Sameer, Patil, Amit, Aware, Umesh, Deshmukh, Prashant, Darji, Brijesh, Sasane, Santosh, Sairam, Kalapatapu V. V. M, Priyadarsiny, Priyanka, Giri, Poonam, Patel, Harilal, Giri, Suresh, Jain, Mukul, Desai, Ranjit C
Published in ACS medicinal chemistry letters (14.01.2016)
Published in ACS medicinal chemistry letters (14.01.2016)
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Melatonin protects against lipid‐induced mitochondrial dysfunction in hepatocytes and inhibits stellate cell activation during hepatic fibrosis in mice
Das, Nabanita, Mandala, Ashok, Naaz, Shamreen, Giri, Suresh, Jain, Mukul, Bandyopadhyay, Debasish, Reiter, Russel J., Roy, Sib Sankar
Published in Journal of pineal research (01.05.2017)
Published in Journal of pineal research (01.05.2017)
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Unraveling the Potential Role of ITecomella undulata/I in Experimental NASH
Srinivas, Akshatha N, Suresh, Diwakar, Suvarna, Deepak, Pathak, Pankaj, Giri, Suresh, Suman, Satish, Suchitha, Chidambaram, Saravana Babu, Kumar, Divya P
Published in International journal of molecular sciences (01.02.2023)
Published in International journal of molecular sciences (01.02.2023)
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Evaluation of novel TGR5 agonist in combination with Sitagliptin for possible treatment of type 2 diabetes
Agarwal, Sameer, Sasane, Santosh, Kumar, Jeevan, Deshmukh, Prashant, Bhayani, Hitesh, Giri, Poonam, Giri, Suresh, Soman, Shubhangi, Kulkarni, Neelima, Jain, Mukul
Published in Bioorganic & medicinal chemistry letters (01.06.2018)
Published in Bioorganic & medicinal chemistry letters (01.06.2018)
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Journal Article
Saroglitazar Delays and Prevents Type 2 Diabetes in db/db Mice
GIRI, SURESH R., BHOI, BIBHUTI B., TRIVEDI, CHITRANG J., RATH, AKSHYAYA C., RATHOD, ROHAN M., JAIN, MUKUL R.
Published in Diabetes (New York, N.Y.) (01.07.2018)
Published in Diabetes (New York, N.Y.) (01.07.2018)
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Discovery of a potent G-protein-coupled receptor 119 agonist for the treatment of type 2 diabetes
Pola, Suresh, Shah, Shailesh R., Pingali, Harikishore, Zaware, Pandurang, Thube, Baban, Makadia, Pankaj, Patel, Hoshang, Bandyopadhyay, Debdutta, Rath, Akshyaya, Giri, Suresh, Patel, Jitendra H., Ranvir, R.K., Sundar, S.R., Patel, Harilal, Kumar, Jeevan, Jain, Mukul R.
Published in Bioorganic & medicinal chemistry (01.04.2021)
Published in Bioorganic & medicinal chemistry (01.04.2021)
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Needle‐free injection system delivery of ZyCoV‐D DNA vaccine demonstrated improved immunogenicity and protective efficacy in rhesus macaques against SARS‐CoV‐2
Yadav, Pragya D., Kumar, Sanjay, Agarwal, Kshitij, Jain, Mukul, Patil, Dilip R., Maithal, Kapil, Mathapati, Basavaraj, Giri, Suresh, Mohandas, Sreelekshmy, Shete, Anita, Sapkal, Gajanan, Patil, Deepak Y., Dey, Ayan, Chandra, Harish, Deshpande, Gururaj, Gupta, Nivedita, Abraham, Priya, Kaushal, Himanshu, Sahay, Rima R., Tripathy, Anuradha, Nyayanit, Dimpal, Jain, Rajlaxmi, Kumar, Abhimanyu, Sarkale, Prasad, Baradkar, Shreekant, Rajanathan, Chozhavel, Raju, Hari Prasad, Patel, Satish, Shah, Niraj, Dwivedi, Pankaj, Singh, Dharmendra
Published in Journal of medical virology (01.02.2023)
Published in Journal of medical virology (01.02.2023)
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ZYDG2, a Potent, Selective, and Safe GPR40 Agonist for Treatment of Type 2 Diabetes
JAIN, MUKUL R., GIRI, SURESH R., TRIVEDI, CHITRANG J., BHOI, BIBHUTI B., RATH, AKSHYAYA CHANDAN, RATHOD, ROHAN MANUBHAI, SUNDAR, RAJESH, BANDYOPADHYAY, DEBDUTTA, RAMDHAVE, RASHMI, PATEL, GAUTAM D., SRIVASTAVA, BRIJESH KUMAR, DESAI, RANJIT C.
Published in Diabetes (New York, N.Y.) (01.07.2018)
Published in Diabetes (New York, N.Y.) (01.07.2018)
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신규의 펩타이드 기재 PCSK9 백신
BAHEKAR RAJESH, JAIN MUKUL, GIRI SURESH, GUPTA GAURAV, CHOPADE RAJENDRA
Year of Publication 07.11.2019
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Year of Publication 07.11.2019
Patent
Identification of an Orally Efficacious GPR40/FFAR1 Receptor Agonist
Agarwal, Sameer, Sasane, Santosh, Deshmukh, Prashant, Rami, Bhadresh, Bandyopadhyay, Debdutta, Giri, Poonam, Giri, Suresh, Jain, Mukul, Desai, Ranjit C
Published in ACS medicinal chemistry letters (08.12.2016)
Published in ACS medicinal chemistry letters (08.12.2016)
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Revisiting glitazars: Thiophene substituted oxazole containing α-ethoxy phenylpropanoic acid derivatives as highly potent PPARα/γ dual agonists devoid of adverse effects in rodents
Raval, Preeti, Jain, Mukul, Goswami, Amitgiri, Basu, Sujay, Gite, Archana, Godha, Atul, Pingali, Harikishore, Raval, Saurin, Giri, Suresh, Suthar, Dinesh, Shah, Maanan, Patel, Pankaj
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
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