Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses
Côté, Bernard, Burch, Jason D., Asante-Appiah, Ernest, Bayly, Chris, Bédard, Leanne, Blouin, Marc, Campeau, Louis-Charles, Cauchon, Elizabeth, Chan, Manuel, Chefson, Amandine, Coulombe, Nathalie, Cromlish, Wanda, Debnath, Smita, Deschênes, Denis, Dupont-Gaudet, Kristina, Falgueyret, Jean-Pierre, Forget, Robert, Gagné, Sébastien, Gauvreau, Danny, Girardin, Melina, Guiral, Sébastien, Langlois, Eric, Li, Chun Sing, Nguyen, Natalie, Papp, Rob, Plamondon, Serge, Roy, Amélie, Roy, Stéphanie, Seliniotakis, Ria, St-Onge, Miguel, Ouellet, Stéphane, Tawa, Paul, Truchon, Jean-François, Vacca, Joe, Wrona, Marc, Yan, Youwei, Ducharme, Yves
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
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Journal Article
A Robust Kilo-Scale Synthesis of Doravirine
Campeau, Louis-Charles, Chen, Qinghao, Gauvreau, Danny, Girardin, Mélina, Belyk, Kevin, Maligres, Peter, Zhou, Guoyue, Gu, Chaozhan, Zhang, Wei, Tan, Lushi, O’Shea, Paul D
Published in Organic process research & development (19.08.2016)
Published in Organic process research & development (19.08.2016)
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Journal Article
Effect of transcranial direct stimulation combined with a functional task on fibromyalgia pain: A case study
Desbiens, Simon, Girardin-Rondeau, Mélina, Guyot-Messier, Loïc, Lamoureux, Dany, Paris, Ludivine, da Silva, Rubens A., Ngomo, Suzy
Published in Neurophysiologie clinique (01.04.2020)
Published in Neurophysiologie clinique (01.04.2020)
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Journal Article
Convergent Kilogram-Scale Synthesis of Dual Orexin Receptor Antagonist
Girardin, Mélina, Ouellet, Stéphane G, Gauvreau, Danny, Moore, Jeffrey C, Hughes, Greg, Devine, Paul N, O’Shea, Paul D, Campeau, Louis-Charles
Published in Organic process research & development (18.01.2013)
Published in Organic process research & development (18.01.2013)
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Journal Article
Training program-induced skeletal muscle adaptations in two men with myotonic dystrophy type 1
Roussel, Marie-Pier, Morin, Marika, Girardin, Mélina, Fortin, Anne-Marie, Leone, Mario, Mathieu, Jean, Gagnon, Cynthia, Duchesne, Elise
Published in BMC research notes (20.08.2019)
Published in BMC research notes (20.08.2019)
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Journal Article
Development of a Practical Synthesis of Stearoyl-CoA Desaturase (SCD1) Inhibitor MK-8245
Girardin, Mélina, Dolman, Sarah J, Lauzon, Sophie, Ouellet, Stéphane G, Hughes, Greg, Fernandez, Paul, Zhou, George, O’Shea, Paul D
Published in Organic process research & development (16.09.2011)
Published in Organic process research & development (16.09.2011)
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Journal Article
Synthesis of 3-Aminoisoxazoles via the Addition−Elimination of Amines on 3-Bromoisoxazolines
Girardin, Mélina, Alsabeh, Pamela G, Lauzon, Sophie, Dolman, Sarah J, Ouellet, Stéphane G, Hughes, Greg
Published in Organic letters (05.03.2009)
Published in Organic letters (05.03.2009)
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Journal Article
Process Research and Scale-up of the κ-Opioid Receptor Agonist CJ-15,161 Drug Candidate
Brian M. Andresen, Brian C. Vanderplas, John L. Tucker, Janice E. Sieser, Maxime Riou, Teresa M. Makowski, Joel M. Hawkins, Melina Girardin, Arun Ghosh, Kristina Dupont-Gaudet, Nga M. Do, Keith M. DeVries, Michel Couturier, Stéphane Caron, Timothy J.N. Watson
Published in Chimia (01.01.2006)
Published in Chimia (01.01.2006)
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Journal Article
Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitors
Leclerc, Jean-Philippe, Falgueyret, Jean-Pierre, Girardin, Mélina, Guay, Jocelyne, Guiral, Sébastien, Huang, Zheng, Li, Chun Sing, Oballa, Renata, Ramtohul, Yeeman K., Skorey, Kathryn, Tawa, Paul, Wang, Hao, Zhang, Lei
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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Journal Article
Synthesis of Highly Functionalized Bicyclo[m.n.1]alkanones via a Cationic Reaction Cascade
Lavigne, Roch M. A, Riou, Maxime, Girardin, Mélina, Morency, Louis, Barriault, Louis
Published in Organic letters (22.12.2005)
Published in Organic letters (22.12.2005)
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Journal Article
Efficient preparation of chiral non-racemic sulfur compounds
Minville, Joannie, Girardin, Mélina, Spino, Claude
Published in Canadian journal of chemistry (01.09.2007)
Published in Canadian journal of chemistry (01.09.2007)
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Journal Article
Cu-Catalyzed N-Arylation of Oxazolidinones: An Efficient Synthesis of the κ-Opioid Receptor Agonist CJ-15161
Ghosh, Arun, Sieser, Janice E, Caron, Stéphane, Couturier, Michel, Dupont-Gaudet, Kristina, Girardin, Melina
Published in Journal of organic chemistry (03.02.2006)
Published in Journal of organic chemistry (03.02.2006)
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Journal Article
Cu-catalyzed N-arylation of oxazolidinones: An efficient synthesis of the k-opioid receptor agonist CJ-15161
Ghosh, A, Sieser, JE, Caron, S, Couturier, M, Dupont-Gaudet, K, Girardin, M
Published in Journal of organic chemistry (03.02.2006)
Published in Journal of organic chemistry (03.02.2006)
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Journal Article
Suzuki Coupling at the 2-Position of Densely Functionalized Pyrimidones
Colarusso, Stefania, Girardin, Melina, Conte, Immacolata, Narjes, Frank
Published in ChemInform (29.08.2006)
Published in ChemInform (29.08.2006)
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Journal Article
Phosphine-Mediated [4 + 2] Annulation of Bis(enones): A Lewis Base Catalyzed “Mock Diels−Alder” Reaction
Couturier, Michel, Ménard, Fréderic, Ragan, John A, Riou, Maxime, Dauphin, Etienne, Andresen, Brian M, Ghosh, Arun, Dupont-Gaudet, Kristina, Girardin, Mélina
Published in Organic letters (27.05.2004)
Published in Organic letters (27.05.2004)
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Journal Article
Synthesis of Highly Functionalized Bicyclo[m.n.1]alkanones via a Cationic Reaction Cascade
Lavigne, Roch M. A., Riou, Maxime, Girardin, Melina, Morency, Louis, Barriault, Louis
Published in ChemInform (09.05.2006)
Published in ChemInform (09.05.2006)
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Journal Article