deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells
Franzolin, Elisa, Pontarin, Giovanna, Rampazzo, Chiara, Miazzi, Cristina, Ferraro, Paola, Palumbo, Elisa, Reichard, Peter, Bianchi, Vera
Published in Proceedings of the National Academy of Sciences - PNAS (27.08.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (27.08.2013)
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Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells
Pontarin, Giovanna, Ferraro, Paola, Bee, Leonardo, Reichard, Peter, Bianchi, Vera
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
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Journal Article
Quantitation of cellular deoxynucleoside triphosphates
Ferraro, Paola, Franzolin, Elisa, Pontarin, Giovanna, Reichard, Peter, Bianchi, Vera
Published in Nucleic acids research (01.04.2010)
Published in Nucleic acids research (01.04.2010)
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Journal Article
Ribonucleotide Reduction Is a Cytosolic Process in Mammalian Cells Independently of DNA Damage
Pontarin, Giovanna, Fijolek, Artur, Pizzo, Paola, Ferraro, Paola, Rampazzo, Chiara, Pozzan, Tullio, Thelander, Lars, Reichard, Peter A., Bianchia, Vera
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2008)
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Journal Article
p53R2-dependent Ribonucleotide Reduction Provides Deoxyribonucleotides in Quiescent Human Fibroblasts in the Absence of Induced DNA Damage
Pontarin, Giovanna, Ferraro, Paola, Håkansson, Pelle, Thelander, Lars, Reichard, Peter, Bianchi, Vera
Published in The Journal of biological chemistry (08.06.2007)
Published in The Journal of biological chemistry (08.06.2007)
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Journal Article
Out of S-phase: Shift of subunits for ribonucleotide reduction
Pontarin, Giovanna, Ferraro, Paola, Reichard, Peter, Bianchi, Vera
Published in Cell cycle (Georgetown, Tex.) (15.11.2012)
Published in Cell cycle (Georgetown, Tex.) (15.11.2012)
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Journal Article
Mitochondrial DNA Depletion and Thymidine Phosphate Pool Dynamics in a Cellular Model of Mitochondrial Neurogastrointestinal Encephalomyopathy
Pontarin, Giovanna, Ferraro, Paola, Valentino, Maria L., Hirano, Michio, Reichard, Peter, Bianchi, Vera
Published in The Journal of biological chemistry (11.08.2006)
Published in The Journal of biological chemistry (11.08.2006)
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Journal Article
Mitochondrial Deoxyribonucleotides, Pool Sizes, Synthesis, and Regulation
Rampazzo, Chiara, Ferraro, Paola, Pontarin, Giovanna, Fabris, Sonia, Reichard, Peter, Bianchi, Vera
Published in The Journal of biological chemistry (23.04.2004)
Published in The Journal of biological chemistry (23.04.2004)
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Journal Article
Mitochondrial Deoxynucleotide Pools in Quiescent Fibroblasts
Ferraro, Paola, Pontarin, Giovanna, Crocco, Laura, Fabris, Sonia, Reichard, Peter, Bianchi, Vera
Published in The Journal of biological chemistry (01.07.2005)
Published in The Journal of biological chemistry (01.07.2005)
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Journal Article
The dNTP triphosphohydrolase activity of SAMHD1 persists during S-phase when the enzyme is phosphorylated at T592
Tramentozzi, Elisa, Ferraro, Paola, Hossain, Manzar, Stillman, Bruce, Bianchi, Vera, Pontarin, Giovanna
Published in Cell cycle (Georgetown, Tex.) (03.05.2018)
Published in Cell cycle (Georgetown, Tex.) (03.05.2018)
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Journal Article
Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
Oberkersch, Roxana E., Pontarin, Giovanna, Astone, Matteo, Spizzotin, Marianna, Arslanbaeva, Liaisan, Tosi, Giovanni, Panieri, Emiliano, Ricciardi, Sara, Allega, Maria Francesca, Brossa, Alessia, Grumati, Paolo, Bussolati, Benedetta, Biffo, Stefano, Tardito, Saverio, Santoro, Massimo M.
Published in Developmental cell (23.05.2022)
Published in Developmental cell (23.05.2022)
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Regulation by degradation, a cellular defense against deoxyribonucleotide pool imbalances
Rampazzo, Chiara, Miazzi, Cristina, Franzolin, Elisa, Pontarin, Giovanna, Ferraro, Paola, Frangini, Miriam, Reichard, Peter, Bianchi, Vera
Published in Mutation research (28.11.2010)
Published in Mutation research (28.11.2010)
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Journal Article
SAMHD1-deficient fibroblasts from Aicardi-Goutières Syndrome patients can escape senescence and accumulate mutations
Franzolin, Elisa, Coletta, Sara, Ferraro, Paola, Pontarin, Giovanna, D'Aronco, Giulia, Stevanoni, Martina, Palumbo, Elisa, Cagnin, Stefano, Bertoldi, Loris, Feltrin, Erika, Valle, Giorgio, Russo, Antonella, Bianchi, Vera, Rampazzo, Chiara
Published in The FASEB journal (01.01.2020)
Published in The FASEB journal (01.01.2020)
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Journal Article
Allosteric Regulation of the Human and Mouse Deoxyribonucleotide Triphosphohydrolase Sterile α-Motif/Histidine-Aspartate Domain-containing Protein 1 (SAMHD1)
Miazzi, Cristina, Ferraro, Paola, Pontarin, Giovanna, Rampazzo, Chiara, Reichard, Peter, Bianchi, Vera
Published in The Journal of biological chemistry (27.06.2014)
Published in The Journal of biological chemistry (27.06.2014)
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Journal Article
Deoxyribonucleotide Metabolism in Cycling and Resting Human Fibroblasts with a Missense Mutation in p53R2, a Subunit of Ribonucleotide Reductase
Pontarin, Giovanna, Ferraro, Paola, Rampazzo, Chiara, Kollberg, Gittan, Holme, Elisabeth, Reichard, Peter, Bianchi, Vera
Published in The Journal of biological chemistry (01.04.2011)
Published in The Journal of biological chemistry (01.04.2011)
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Journal Article
Mitochondrial deoxynucleotide pools in quiescent fibroblasts: a possible model for mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)
Ferraro, Paola, Pontarin, Giovanna, Crocco, Laura, Fabris, Sonia, Reichard, Peter, Bianchi, Vera
Published in The Journal of biological chemistry (01.07.2005)
Published in The Journal of biological chemistry (01.07.2005)
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