Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
Fares, Iman, Chagraoui, Jalila, Gareau, Yves, Gingras, Stéphane, Ruel, Réjean, Mayotte, Nadine, Csaszar, Elizabeth, Knapp, David J. H. F., Miller, Paul, Ngom, Mor, Imren, Suzan, Roy, Denis-Claude, Watts, Kori L., Kiem, Hans-Peter, Herrington, Robert, Iscove, Norman N., Humphries, R. Keith, Eaves, Connie J., Cohen, Sandra, Marinier, Anne, Zandstra, Peter W., Sauvageau, Guy
Published in Science (American Association for the Advancement of Science) (19.09.2014)
Published in Science (American Association for the Advancement of Science) (19.09.2014)
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Journal Article
Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
Baccelli, Irène, Gareau, Yves, Lehnertz, Bernhard, Gingras, Stéphane, Spinella, Jean-François, Corneau, Sophie, Mayotte, Nadine, Girard, Simon, Frechette, Mélanie, Blouin-Chagnon, Valérie, Leveillé, Koryne, Boivin, Isabel, MacRae, Tara, Krosl, Jana, Thiollier, Clarisse, Lavallée, Vincent-Philippe, Kanshin, Evgeny, Bertomeu, Thierry, Coulombe-Huntington, Jasmin, St-Denis, Corinne, Bordeleau, Marie-Eve, Boucher, Geneviève, Roux, Philippe P., Lemieux, Sébastien, Tyers, Mike, Thibault, Pierre, Hébert, Josée, Marinier, Anne, Sauvageau, Guy
Published in Cancer cell (08.07.2019)
Published in Cancer cell (08.07.2019)
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Journal Article
A diene-transmissive approach to the quassinoid skeleton
Spino, Claude, Hill, Bryan, Dubé, Pascal, Gingras, Stéphane
Published in Canadian journal of chemistry (01.01.2003)
Published in Canadian journal of chemistry (01.01.2003)
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Journal Article
Synthesis of Potent and Orally Efficacious 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor HSD-016
Wan, Zhao-Kui, Chenail, Eva, Li, Huan-Qiu, Kendall, Christopher, Wang, Youchu, Gingras, Stéphane, Xiang, Jason, Massefski, Walter W, Mansour, Tarek, S, Saiah, Eddine
Published in Journal of organic chemistry (02.09.2011)
Published in Journal of organic chemistry (02.09.2011)
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The Process Development of Ravuconazole: An Efficient Multikilogram Scale Preparation of an Antifungal Agent
Pesti, Jaan, Chen, Chien-Kuang, Spangler, Lori, DelMonte, Albert J, Benoit, Serge, Berglund, Derek, Bien, Jeffrey, Brodfuehrer, Paul, Chan, Yeung, Corbett, Elisabeth, Costello, Carrie, DeMena, Paul, Discordia, Robert P, Doubleday, Wendel, Gao, Zhinong, Gingras, Stephane, Grosso, John, Haas, Oscar, Kacsur, David, Lai, Chiajen, Leung, Simon, Miller, Melanie, Muslehiddinoglu, Jale, Nguyen, Nina, Qiu, Jun, Olzog, Martina, Reiff, Emily, Thoraval, Dominique, Totleben, Michael, Vanyo, Dale, Vemishetti, Purushotham, Wasylak, John, Wei, Chenkou
Published in Organic process research & development (17.07.2009)
Published in Organic process research & development (17.07.2009)
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Journal Article
Kilogram Synthesis of a Selective Serotonin Reuptake Inhibitor
Anthes, Robert, Bello, Osagie, Benoit, Serge, Chen, Chien-Kuang, Corbett, Elisabeth, Corbett, Richard M, DelMonte, Albert J, Gingras, Stephane, Livingston, Robert, Sausker, Justin, Soumeillant, Maxime
Published in Organic process research & development (01.03.2008)
Published in Organic process research & development (01.03.2008)
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Journal Article
Pyrimido-Indole Derivatives Are Novel Agonists of Human Cord Blood Hematopoietic Stem Cell Self-Renewal
Fares, Iman, Chagaroui, Jalila, Gareau, Yves, Gingras, Stéphane, Mayotte, Nadine, Csaszar, Elizabeth, Kiem, Hans-Peter, Iscove, Norman N., Humphries, R. Keith, Eaves, Connie J., Cohen, Sandra, Marinier, Anne, Zandstra, Peter W., Sauvageau, Guy
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
1023 – THE IMPORTANCE OF STEM CELL EXPANSION IN TOMORROW'S MEDICINE
Sauvageau, Guy, Chagraoui, Jalila, Tomellini, Elisa, Rojas-Sutterlin, Shanti, Corneau, Sophie, Girard, Simon, Tellelchea, Maria Florencia, Gingras, Stephane, Gareau, Yves, Ruel, Rejean, Cohen, Sandra, Milano, Filippo, Marinier, Anne
Published in Experimental hematology (2022)
Published in Experimental hematology (2022)
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Journal Article
Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
Fares, Iman, Chagraoui, Jalila, Gareau, Yves, Gingras, Stéphane, Ruel, Réjean, Mayotte, Nadine, Csaszar, Elizabeth, Knapp, David J H F, Miller, Paul, Ngom, Mor, Imren, Suzan, Roy, Denis-Claude, Watts, Kori L, Kiem, Hans-Peter, Herrington, Robert, Iscove, Norman N, Humphries, R Keith, Eaves, Connie J, Cohen, Sandra, Marinier, Anne, Zandstra, Peter W, Sauvageau, Guy
Published in Science (American Association for the Advancement of Science) (19.09.2014)
Published in Science (American Association for the Advancement of Science) (19.09.2014)
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Journal Article
HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF
SAUVAGEAU, Guy, GINGRAS, Stéphane, MARINIER, Anne, GAREAU, Yves, CHANTIGNY, Yves, BACCELLI, Irène, YANG, Gaoqiang
Year of Publication 09.10.2024
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Year of Publication 09.10.2024
Patent
HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF
SAUVAGEAU, Guy, GINGRAS, Stéphane, MARINIER, Anne, GAREAU, Yves, CHANTIGNY, Yves, BACCELLI, Irène, YANG, Gaoqiang
Year of Publication 09.11.2023
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Year of Publication 09.11.2023
Patent
Heterocyclic mitochondrial activity inhibitors and uses thereof
Gingras, Stéphane, Baccelli, Irène, Sauvageau, Guy, Marinier, Anne, Gareau, Yves, Yang, Gaoqiang, Chantigny, Yves
Year of Publication 19.09.2023
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Year of Publication 19.09.2023
Patent
Heterocyclic mitochondrial activity inhibitors and uses thereof
SAUVAGEAU, Guy, GINGRAS, Stéphane, MARINIER, Anne, GAREAU, Yves, CHANTIGNY, Yves, BACCELLI, Irène, YANG, Gaoqiang
Year of Publication 13.07.2023
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Year of Publication 13.07.2023
Patent
Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia
Baccelli, Irene, Gareau, Yves, Lehnertz, Bernhard, Stephane, Gingras, Spinella, Jean-Francois, Beautrait, Alexandre, Corneau, Sophie, Mayotte, Nadine, Boivin, Isabel, Girard, Simon, MacRae, Tara, Frechette, Melanie, Leveille, Koryne, Krosl, Jana, Thiollier, Clarisse, Kanshin, Evgeny, Bertomeu, Thierry, Coulombe-Huntington, Jasmin, St-Denis, Corinne, Bordeleau, Marie-Eve, Boucher, Geneviève, Roux, Philippe P, Lemieux, Sébastien, Tyers, Mike, Thibault, Pierre, Marinier, Anne, Hébert, Josée, Sauvageau, Guy
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF
Gingras, Stéphane, Baccelli, Irène, Sauvageau, Guy, Marinier, Anne, Gareau, Yves, Yang, Gaoqiang, Chantigny, Yves
Year of Publication 16.12.2021
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Year of Publication 16.12.2021
Patent
PYRIMIDO[4,5-B]INDOLE DERIVATIVES AND USE THEREOF IN THE EXPANSION OF HEMATOPOIETIC STEM CELLS
Ruel, Réjean, Gingras, Stéphane, Fares, Iman, Sauvageau, Guy, Gareau, Yves
Year of Publication 04.10.2019
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Year of Publication 04.10.2019
Patent
PYRIMIDO[4,5-B]INDOLE DERIVATIVES AND USE THEREOF IN THE EXPANSION OF HEMATOPOIETIC STEM CELLS
SAUVAGEAU, GUY, RUEL, RÉJEAN, GAREAU, YVES, FARES, IMAN, GINGRAS, STÉPHANE
Year of Publication 30.09.2019
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Year of Publication 30.09.2019
Patent