Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics
Torrents de la Peña, Alba, Rantalainen, Kimmo, Cottrell, Christopher A, Allen, Joel D, van Gils, Marit J, Torres, Jonathan L, Crispin, Max, Sanders, Rogier W, Ward, Andrew B
Published in PLoS pathogens (01.07.2019)
Published in PLoS pathogens (01.07.2019)
Get full text
Journal Article
Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers
Blattner, Claudia, Lee, Jeong Hyun, Sliepen, Kwinten, Derking, Ronald, Falkowska, Emilia, de la Peña, Alba Torrents, Cupo, Albert, Julien, Jean-Philippe, van Gils, Marit, Lee, Peter S., Peng, Wenjie, Paulson, James C., Poignard, Pascal, Burton, Dennis R., Moore, John P., Sanders, Rogier W., Wilson, Ian A., Ward, Andrew B.
Published in Immunity (Cambridge, Mass.) (15.05.2014)
Published in Immunity (Cambridge, Mass.) (15.05.2014)
Get full text
Journal Article
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques
Klasse, P J, Ketas, Thomas J, Cottrell, Christopher A, Ozorowski, Gabriel, Debnath, Gargi, Camara, Diawoye, Francomano, Erik, Pugach, Pavel, Ringe, Rajesh P, LaBranche, Celia C, van Gils, Marit J, Bricault, Christine A, Barouch, Dan H, Crotty, Shane, Silvestri, Guido, Kasturi, Sudhir, Pulendran, Bali, Wilson, Ian A, Montefiori, David C, Sanders, Rogier W, Ward, Andrew B, Moore, John P
Published in PLoS pathogens (23.02.2018)
Published in PLoS pathogens (23.02.2018)
Get full text
Journal Article
Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice
Dosenovic, Pia, von Boehmer, Lotta, Escolano, Amelia, Jardine, Joseph, Freund, Natalia T., Gitlin, Alexander D., McGuire, Andrew T., Kulp, Daniel W., Oliveira, Thiago, Scharf, Louise, Pietzsch, John, Gray, Matthew D., Cupo, Albert, van Gils, Marit J., Yao, Kai-Hui, Liu, Cassie, Gazumyan, Anna, Seaman, Michael S., Björkman, Pamela J., Sanders, Rogier W., Moore, John P., Stamatatos, Leonidas, Schief, William R., Nussenzweig, Michel C.
Published in Cell (18.06.2015)
Published in Cell (18.06.2015)
Get full text
Journal Article
Antigenic cartography using sera from sequence-confirmed SARS-CoV-2 variants of concern infections reveals antigenic divergence of Omicron
van der Straten, Karlijn, Guerra, Denise, van Gils, Marit J., Bontjer, Ilja, Caniels, Tom G., van Willigen, Hugo D.G., Wynberg, Elke, Poniman, Meliawati, Burger, Judith A., Bouhuijs, Joey H., van Rijswijk, Jacqueline, Olijhoek, Wouter, Liesdek, Marinus H., Lavell, A.H. Ayesha, Appelman, Brent, Sikkens, Jonne J., Bomers, Marije K., Han, Alvin X., Nichols, Brooke E., Prins, Maria, Vennema, Harry, Reusken, Chantal, de Jong, Menno D., de Bree, Godelieve J., Russell, Colin A., Eggink, Dirk, Sanders, Rogier W.
Published in Immunity (13.09.2022)
Published in Immunity (13.09.2022)
Get full text
Journal Article
Web Resource
Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies
McCoy, Laura E., van Gils, Marit J., Ozorowski, Gabriel, Messmer, Terrence, Briney, Bryan, Voss, James E., Kulp, Daniel W., Macauley, Matthew S., Sok, Devin, Pauthner, Matthias, Menis, Sergey, Cottrell, Christopher A., Torres, Jonathan L., Hsueh, Jessica, Schief, William R., Wilson, Ian A., Ward, Andrew B., Sanders, Rogier W., Burton, Dennis R.
Published in Cell reports (Cambridge) (30.08.2016)
Published in Cell reports (Cambridge) (30.08.2016)
Get full text
Journal Article
Cross-Reactive Neutralizing Humoral Immunity Does Not Protect from HIV Type 1 Disease Progression
Euler, Zelda, van Gils, Marit J., Bunnik, Evelien M., Phung, Pham, Schweighardt, Becky, Wrin, Terri, Schuitemaker, Hanneke
Published in The Journal of infectious diseases (01.04.2010)
Published in The Journal of infectious diseases (01.04.2010)
Get full text
Journal Article
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants
Yuan, Meng, Huang, Deli, Lee, Chang-Chun D, Wu, Nicholas C, Jackson, Abigail M, Zhu, Xueyong, Liu, Hejun, Peng, Linghang, van Gils, Marit J, Sanders, Rogier W, Burton, Dennis R, Reincke, S Momsen, Prüss, Harald, Kreye, Jakob, Nemazee, David, Ward, Andrew B, Wilson, Ian A
Published in Science (13.08.2021)
Published in Science (13.08.2021)
Get full text
Journal Article
Web Resource
Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity
Liu, Hejun, Wu, Nicholas C., Yuan, Meng, Bangaru, Sandhya, Torres, Jonathan L., Caniels, Tom G., van Schooten, Jelle, Zhu, Xueyong, Lee, Chang-Chun D., Brouwer, Philip J.M., van Gils, Marit J., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
Published in Immunity (Cambridge, Mass.) (15.12.2020)
Published in Immunity (Cambridge, Mass.) (15.12.2020)
Get full text
Journal Article
The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection
Charles, Tysheena P, Burton, Samantha L, Arunachalam, Prabhu S, Cottrell, Christopher A, Sewall, Leigh M, Bollimpelli, Venkata S, Gangadhara, Sailaja, Dey, Antu K, Ward, Andrew B, Shaw, George M, Hunter, Eric, Amara, Rama R, Pulendran, Bali, van Gils, Marit J, Derdeyn, Cynthia A
Published in PLoS pathogens (01.02.2021)
Published in PLoS pathogens (01.02.2021)
Get full text
Journal Article
The effect of spike mutations on SARS-CoV-2 neutralization
Rees-Spear, Chloe, Muir, Luke, Griffith, Sarah A., Heaney, Judith, Aldon, Yoann, Snitselaar, Jonne L., Thomas, Peter, Graham, Carl, Seow, Jeffrey, Lee, Nayung, Rosa, Annachiara, Roustan, Chloe, Houlihan, Catherine F., Sanders, Rogier W., Gupta, Ravindra K., Cherepanov, Peter, Stauss, Hans J., Nastouli, Eleni, Doores, Katie J., van Gils, Marit J., McCoy, Laura E.
Published in Cell reports (Cambridge) (23.03.2021)
Published in Cell reports (Cambridge) (23.03.2021)
Get full text
Journal Article
A SARS-CoV-2 Wuhan spike virosome vaccine induces superior neutralization breadth compared to one using the Beta spike
van der Velden, Yme U, Grobben, Marloes, Caniels, Tom G, Burger, Judith A, Poniman, Meliawati, Oomen, Melissa, Rijnstra, Esther Siteur-van, Tejjani, Khadija, Guerra, Denise, Kempers, Ronald, Stegmann, Toon, van Gils, Marit J, Sanders, Rogier W
Published in Scientific reports (10.03.2022)
Published in Scientific reports (10.03.2022)
Get full text
Journal Article
An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain
Wu, Nicholas C., Yuan, Meng, Liu, Hejun, Lee, Chang-Chun D., Zhu, Xueyong, Bangaru, Sandhya, Torres, Jonathan L., Caniels, Tom G., Brouwer, Philip J.M., van Gils, Marit J., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
Published in Cell Reports (20.10.2020)
Published in Cell Reports (20.10.2020)
Get full text
Journal Article
Web Resource
Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant
Graham, Carl, Seow, Jeffrey, Huettner, Isabella, Khan, Hataf, Kouphou, Neophytos, Acors, Sam, Winstone, Helena, Pickering, Suzanne, Galao, Rui Pedro, Dupont, Liane, Lista, Maria Jose, Jimenez-Guardeño, Jose M., Laing, Adam G., Wu, Yin, Joseph, Magdalene, Muir, Luke, van Gils, Marit J., Ng, Weng M., Duyvesteyn, Helen M.E., Zhao, Yuguang, Bowden, Thomas A., Shankar-Hari, Manu, Rosa, Annachiara, Cherepanov, Peter, McCoy, Laura E., Hayday, Adrian C., Neil, Stuart J.D., Malim, Michael H., Doores, Katie J.
Published in Immunity (Cambridge, Mass.) (08.06.2021)
Published in Immunity (Cambridge, Mass.) (08.06.2021)
Get full text
Journal Article
Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody
Schommers, Philipp, Gruell, Henning, Abernathy, Morgan E., Tran, My-Kim, Dingens, Adam S., Gristick, Harry B., Barnes, Christopher O., Schoofs, Till, Schlotz, Maike, Vanshylla, Kanika, Kreer, Christoph, Weiland, Daniela, Holtick, Udo, Scheid, Christof, Valter, Markus M., van Gils, Marit J., Sanders, Rogier W., Vehreschild, Jörg J., Cornely, Oliver A., Lehmann, Clara, Fätkenheuer, Gerd, Seaman, Michael S., Bloom, Jesse D., Bjorkman, Pamela J., Klein, Florian
Published in Cell (06.02.2020)
Published in Cell (06.02.2020)
Get full text
Journal Article
Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex
Sok, Devin, van Gils, Marit J., Pauthner, Matthias, Julien, Jean-Philippe, Saye-Francisco, Karen L., Hsueh, Jessica, Briney, Bryan, Lee, Jeong Hyun, Le, Khoa M., Lee, Peter S., Hua, Yuanzi, Seaman, Michael S., Moore, John P., Ward, Andrew B., Wilson, Ian A., Sanders, Rogier W., Burton, Dennis R.
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.2014)
Get full text
Journal Article
Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle
Brouwer, Philip J M, Antanasijevic, Aleksandar, Berndsen, Zachary, Yasmeen, Anila, Fiala, Brooke, Bijl, Tom P L, Bontjer, Ilja, Bale, Jacob B, Sheffler, William, Allen, Joel D, Schorcht, Anna, Burger, Judith A, Camacho, Miguel, Ellis, Daniel, Cottrell, Christopher A, Behrens, Anna-Janina, Catalano, Marco, Del Moral-Sánchez, Iván, Ketas, Thomas J, LaBranche, Celia, van Gils, Marit J, Sliepen, Kwinten, Stewart, Lance J, Crispin, Max, Montefiori, David C, Baker, David, Moore, John P, Klasse, Per Johan, Ward, Andrew B, King, Neil P, Sanders, Rogier W
Published in Nature communications (19.09.2019)
Published in Nature communications (19.09.2019)
Get full text
Journal Article
A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies
Sanders, Rogier W, Derking, Ronald, Cupo, Albert, Julien, Jean-Philippe, Yasmeen, Anila, de Val, Natalia, Kim, Helen J, Blattner, Claudia, de la Peña, Alba Torrents, Korzun, Jacob, Golabek, Michael, de Los Reyes, Kevin, Ketas, Thomas J, van Gils, Marit J, King, C Richter, Wilson, Ian A, Ward, Andrew B, Klasse, P J, Moore, John P
Published in PLoS pathogens (01.09.2013)
Published in PLoS pathogens (01.09.2013)
Get full text
Journal Article
The effect of SARS-CoV-2 vaccination on post-acute sequelae of COVID-19 (PASC): A prospective cohort study
Wynberg, Elke, Han, Alvin X., Boyd, Anders, van Willigen, Hugo D.G., Verveen, Anouk, Lebbink, Romy, van der Straten, Karlijn, Kootstra, Neeltje, van Gils, Marit J., Russell, Colin, Leenstra, Tjalling, de Jong, Menno D., de Bree, Godelieve J., Prins, Maria
Published in Vaccine (30.07.2022)
Published in Vaccine (30.07.2022)
Get full text
Journal Article