Molecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development
Dorssers, Lambert C J, Gillis, Ad J M, Stoop, Hans, van Marion, Ronald, Nieboer, Marleen M, van Riet, Job, van de Werken, Harmen J G, Oosterhuis, J Wolter, de Ridder, Jeroen, Looijenga, Leendert H J
Published in British journal of cancer (01.02.2019)
Published in British journal of cancer (01.02.2019)
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Journal Article
Genome wide DNA methylation profiles provide clues to the origin and pathogenesis of germ cell tumors
Rijlaarsdam, Martin A, Tax, David M J, Gillis, Ad J M, Dorssers, Lambert C J, Koestler, Devin C, de Ridder, Jeroen, Looijenga, Leendert H J
Published in PloS one (10.04.2015)
Published in PloS one (10.04.2015)
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Journal Article
Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence
Xu, Lin, Pierce, Joshua L, Sanchez, Angelica, Chen, Kenneth S, Shukla, Abhay A, Fustino, Nicholas J, Stuart, Sarai H, Bagrodia, Aditya, Xiao, Xue, Guo, Lei, Krailo, Mark D, Shaikh, Furqan, Billmire, Deborah F, Pashankar, Farzana, Bestrashniy, Jessica, Oosterhuis, J Wolter, Gillis, Ad J M, Xie, Yang, Teot, Lisa, Mora, Jaume, Poynter, Jenny N, Rakheja, Dinesh, Looijenga, Leendert H J, Draper, Bruce W, Frazier, A Lindsay, Amatruda, James F
Published in Nature communications (06.05.2023)
Published in Nature communications (06.05.2023)
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Journal Article
Endogenous Nodal signaling regulates germ cell potency during mammalian testis development
Spiller, Cassy M, Feng, Chun-Wei, Jackson, Andrew, Gillis, Ad J M, Rolland, Antoine D, Looijenga, Leendert H J, Koopman, Peter, Bowles, Josephine
Published in Development (Cambridge) (15.11.2012)
Published in Development (Cambridge) (15.11.2012)
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Journal Article
Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline
Giannoulatou, Eleni, Maher, Geoffrey J, Ding, Zhihao, Gillis, Ad J M, Dorssers, Lambert C J, Hoischen, Alexander, Rajpert-De Meyts, Ewa, McVean, Gilean, Wilkie, Andrew O M, Looijenga, Leendert H J, Goriely, Anne
Published in PloS one (22.05.2017)
Published in PloS one (22.05.2017)
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Journal Article
Humanised Mice and Immunodeficient Mice (NSG) Are Equally Sensitive for Prediction of Stem Cell Malignancy in the Teratoma Assay
Bialecka, Monika, Montilla-Rojo, Joaquin, Roelen, Bernard A J, Gillis, Ad J, Looijenga, Leendert H J, Salvatori, Daniela C F
Published in International journal of molecular sciences (23.04.2022)
Published in International journal of molecular sciences (23.04.2022)
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Journal Article
Napabucasin overcomes cisplatin resistance in ovarian germ cell tumor-derived cell line by inhibiting cancer stemness
Schmidtova, Silvia, Dorssers, Lambert C J, Kalavska, Katarina, Gillis, Ad J M, Oosterhuis, J Wolter, Stoop, Hans, Miklikova, Svetlana, Kozovska, Zuzana, Burikova, Monika, Gercakova, Katarina, Durinikova, Erika, Chovanec, Michal, Mego, Michal, Kucerova, Lucia, Looijenga, Leendert H J
Published in Cancer cell international (03.08.2020)
Published in Cancer cell international (03.08.2020)
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Journal Article
Microsatellite Instability, Mismatch Repair Deficiency, and BRAF Mutation in Treatment-Resistant Germ Cell Tumors
HONECKER, Friedemann, WERMANN, Hendrik, WOLTER OOSTERHUIS, J, BOKEMEYER, Carsten, LOOIJENGA, Leendert H. J, MAYER, Frank, GILLIS, Ad J. M, STOOP, Hans, VAN GURP, Ruud J. L. M, OECHSLE, Karin, STEYERBERG, Ewout, HARTMANN, Jörg Th, DINJENS, Winand N. M
Published in Journal of clinical oncology (01.05.2009)
Published in Journal of clinical oncology (01.05.2009)
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Journal Article
Seminoma and embryonal carcinoma footprints identified by analysis of integrated genome-wide epigenetic and expression profiles of germ cell cancer cell lines
van der Zwan, Yvonne G, Rijlaarsdam, Martin A, Rossello, Fernando J, Notini, Amanda J, de Boer, Suzan, Watkins, D Neil, Gillis, Ad J M, Dorssers, Lambert C J, White, Stefan J, Looijenga, Leendert H J
Published in PloS one (02.06.2014)
Published in PloS one (02.06.2014)
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Journal Article
Serum microRNA profiles in athyroid patients on and off levothyroxine therapy
Massolt, Elske T, Chaker, Layal, Visser, Theo J, Gillis, Ad J M, Dorssers, Lambert C J, Beukhof, Carolien M, Kam, Boen L R, Franssen, Gaston J, Brigante, Giulia, van Ginhoven, Tessa M, Visser, W Edward, Looijenga, Leendert H J, Peeters, Robin P
Published in PloS one (12.04.2018)
Published in PloS one (12.04.2018)
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Journal Article
The Role of TP53 in Cisplatin Resistance in Mediastinal and Testicular Germ Cell Tumors
Timmerman, Dennis M, Eleveld, Thomas F, Gillis, Ad J M, Friedrichs, Carlijn C, Hillenius, Sanne, Remmers, Tessa L, Sriram, Sruthi, Looijenga, Leendert H J
Published in International journal of molecular sciences (29.10.2021)
Published in International journal of molecular sciences (29.10.2021)
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Journal Article
Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance
Wermann, Hendrik, Stoop, Hans, Gillis, Ad JM, Honecker, Friedemann, van Gurp, Ruud JHLM, Ammerpohl, Ole, Richter, Julia, Oosterhuis, J. Wolter, Bokemeyer, Carsten, Looijenga, Leendert HJ
Published in The Journal of pathology (01.08.2010)
Published in The Journal of pathology (01.08.2010)
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Journal Article
Identification and Validation Model for Informative Liquid Biopsy-Based microRNA Biomarkers: Insights from Germ Cell Tumor In Vitro, In Vivo and Patient-Derived Data
Lobo, João, Gillis, Ad J M, van den Berg, Annette, Dorssers, Lambert C J, Belge, Gafanzer, Dieckmann, Klaus-Peter, Roest, Henk P, van der Laan, Luc J W, Gietema, Jourik, Hamilton, Robert J, Jerónimo, Carmen, Henrique, Rui, Salvatori, Daniela, Looijenga, Leendert H J
Published in Cells (Basel, Switzerland) (14.12.2019)
Published in Cells (Basel, Switzerland) (14.12.2019)
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Journal Article
Imprints and DPPA3 are bypassed during pluripotency- and differentiation-coupled methylation reprogramming in testicular germ cell tumors
Killian, J Keith, Dorssers, Lambert C J, Trabert, Britton, Gillis, Ad J M, Cook, Michael B, Wang, Yonghong, Waterfall, Joshua J, Stevenson, Holly, Smith, Jr, William I, Noyes, Natalia, Retnakumar, Parvathy, Stoop, J Hans, Oosterhuis, J Wolter, Meltzer, Paul S, McGlynn, Katherine A, Looijenga, Leendert H J
Published in Genome research (01.11.2016)
Published in Genome research (01.11.2016)
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Journal Article
Mutations in LRRC50 predispose zebrafish and humans to seminomas
Basten, Sander G, Davis, Erica E, Gillis, Ad J M, van Rooijen, Ellen, Stoop, Hans, Babala, Nikolina, Logister, Ive, Heath, Zachary G, Jonges, Trudy N, Katsanis, Nicholas, Voest, Emile E, van Eeden, Freek J, Medema, Rene H, Ketting, René F, Schulte-Merker, Stefan, Looijenga, Leendert H J, Giles, Rachel H
Published in PLoS genetics (01.04.2013)
Published in PLoS genetics (01.04.2013)
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Journal Article
Combining Hypermethylated RASSF1A Detection Using ddPCR with miR-371a-3p Testing: An Improved Panel of Liquid Biopsy Biomarkers for Testicular Germ Cell Tumor Patients
Lobo, João, van Zogchel, Lieke M J, Nuru, Mohammed G, Gillis, Ad J M, van der Schoot, C Ellen, Tytgat, Godelieve A M, Looijenga, Leendert H J
Published in Cancers (18.10.2021)
Published in Cancers (18.10.2021)
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Journal Article
Comparative Analyses of Liquid-Biopsy MicroRNA371a-3p Isolation Protocols for Serum and Plasma
Timmerman, Dennis M., Gillis, Ad J. M., Mego, Michal, Looijenga, Leendert H. J.
Published in Cancers (24.08.2021)
Published in Cancers (24.08.2021)
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Journal Article