Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
Viswanathan, Vasanthi S, Ryan, Matthew J, Dhruv, Harshil D, Gill, Shubhroz, Eichhoff, Ossia M, Seashore-Ludlow, Brinton, Kaffenberger, Samuel D, Eaton, John K, Shimada, Kenichi, Aguirre, Andrew J, Viswanathan, Srinivas R, Chattopadhyay, Shrikanta, Tamayo, Pablo, Yang, Wan Seok, Rees, Matthew G, Chen, Sixun, Boskovic, Zarko V, Javaid, Sarah, Huang, Cherrie, Wu, Xiaoyun, Tseng, Yuen-Yi, Roider, Elisabeth M, Gao, Dong, Cleary, James M, Wolpin, Brian M, Mesirov, Jill P, Haber, Daniel A, Engelman, Jeffrey A, Boehm, Jesse S, Kotz, Joanne D, Hon, Cindy S, Chen, Yu, Hahn, William C, Levesque, Mitchell P, Doench, John G, Berens, Michael E, Shamji, Alykhan F, Clemons, Paul A, Stockwell, Brent R, Schreiber, Stuart L
Published in Nature (London) (27.07.2017)
Published in Nature (London) (27.07.2017)
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Journal Article
Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet
Hatori, Megumi, Vollmers, Christopher, Zarrinpar, Amir, DiTacchio, Luciano, Bushong, Eric A., Gill, Shubhroz, Leblanc, Mathias, Chaix, Amandine, Joens, Matthew, Fitzpatrick, James A.J., Ellisman, Mark H., Panda, Satchidananda
Published in Cell metabolism (06.06.2012)
Published in Cell metabolism (06.06.2012)
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Journal Article
Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression
Vollmers, Christopher, Gill, Shubhroz, DiTacchio, Luciano, Pulivarthy, Sandhya R, Le, Hiep D, Panda, Satchidananda
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2009)
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Journal Article
Correlating chemical sensitivity and basal gene expression reveals mechanism of action
Rees, Matthew G, Seashore-Ludlow, Brinton, Cheah, Jaime H, Adams, Drew J, Price, Edmund V, Gill, Shubhroz, Javaid, Sarah, Coletti, Matthew E, Jones, Victor L, Bodycombe, Nicole E, Soule, Christian K, Alexander, Benjamin, Li, Ava, Montgomery, Philip, Kotz, Joanne D, Hon, C Suk-Yee, Munoz, Benito, Liefeld, Ted, Dančík, Vlado, Haber, Daniel A, Clish, Clary B, Bittker, Joshua A, Palmer, Michelle, Wagner, Bridget K, Clemons, Paul A, Shamji, Alykhan F, Schreiber, Stuart L
Published in Nature chemical biology (01.02.2016)
Published in Nature chemical biology (01.02.2016)
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Journal Article
Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank
Lane, Jacqueline M, Vlasac, Irma, Anderson, Simon G, Kyle, Simon D, Dixon, William G, Bechtold, David A, Gill, Shubhroz, Little, Max A, Luik, Annemarie, Loudon, Andrew, Emsley, Richard, Scheer, Frank A J L, Lawlor, Deborah A, Redline, Susan, Ray, David W, Rutter, Martin K, Saxena, Richa
Published in Nature communications (09.03.2016)
Published in Nature communications (09.03.2016)
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Journal Article
Lhx1 maintains synchrony among circadian oscillator neurons of the SCN
Hatori, Megumi, Gill, Shubhroz, Mure, Ludovic S, Goulding, Martyn, O'Leary, Dennis D M, Panda, Satchidananda
Published in eLife (17.07.2014)
Published in eLife (17.07.2014)
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Journal Article
Small-Molecule Control of Super-Mendelian Inheritance in Gene Drives
López Del Amo, Víctor, Leger, Brittany S., Cox, Kurt J., Gill, Shubhroz, Bishop, Alena L., Scanlon, Garrett D., Walker, James A., Gantz, Valentino M., Choudhary, Amit
Published in Cell reports (Cambridge) (30.06.2020)
Published in Cell reports (Cambridge) (30.06.2020)
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Journal Article
Integrated genetic and pharmacologic interrogation of rare cancers
Hong, Andrew L, Tseng, Yuen-Yi, Cowley, Glenn S, Jonas, Oliver, Cheah, Jaime H, Kynnap, Bryan D, Doshi, Mihir B, Oh, Coyin, Meyer, Stephanie C, Church, Alanna J, Gill, Shubhroz, Bielski, Craig M, Keskula, Paula, Imamovic, Alma, Howell, Sara, Kryukov, Gregory V, Clemons, Paul A, Tsherniak, Aviad, Vazquez, Francisca, Crompton, Brian D, Shamji, Alykhan F, Rodriguez-Galindo, Carlos, Janeway, Katherine A, Roberts, Charles W M, Stegmaier, Kimberly, van Hummelen, Paul, Cima, Michael J, Langer, Robert S, Garraway, Levi A, Schreiber, Stuart L, Root, David E, Hahn, William C, Boehm, Jesse S
Published in Nature communications (22.06.2016)
Published in Nature communications (22.06.2016)
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Journal Article
Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits
Lane, Jacqueline M, Liang, Jingjing, Vlasac, Irma, Anderson, Simon G, Bechtold, David A, Bowden, Jack, Emsley, Richard, Gill, Shubhroz, Little, Max A, Luik, Annemarie I, Loudon, Andrew, Scheer, Frank A J L, Purcell, Shaun M, Kyle, Simon D, Lawlor, Deborah A, Zhu, Xiaofeng, Redline, Susan, Ray, David W, Rutter, Martin K, Saxena, Richa
Published in Nature genetics (01.02.2017)
Published in Nature genetics (01.02.2017)
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Journal Article
Abstract B17: Identification of Druggable Targets through Functional Multi-Omics in Renal Medullary Carcinoma
Hong, Andrew L., Tseng, Yuen-Yi, Kynnap, Bryan D., Doshi, Mihir B., Sandoval, Gabriel, Oh, Coyin, Sayeed, Abeer, Shubhroz, Gill, Church, Alanna J., Keskula, Paula, Peng, Anson, Clemons, Paul A., Tsherniak, Aviad, Vazquez, Francisca, Rodriguez-Galindo, Carlos, Janeway, Katherine A., Garraway, Levi A., Schreiber, Stuart L., Root, David E., Mullen, Elizabeth, Stegmaier, Kimberly, Kadoch, Cigall, Roberts, Charles W.M., Boehm, Jesse S., Hahn, William C.
Published in Molecular cancer therapeutics (01.10.2017)
Published in Molecular cancer therapeutics (01.10.2017)
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Journal Article
Abstract A02: Expanding tumor chemical-genetic interaction map using next-generation cancer models
Tseng, Yuen-Yi (Moony), Hong, Andrew, Gill, Shubhroz, Keskula, Paula, Raghavan, Srivatsan, Cheah, Jaime, Tsherniak, Aviad, Vazquez, Francisca, Alkhairy, Sahar, Peng, Anson, Sayeed, Abeer, Deasy, Rebecca, Ronning, Peter, Kantoff, Philip, Garraway, Levi, Rubin, Mark, Kuo, Calvin, Puram, Sidharth, Gazdar, Adi, Wagle, Nikhil, Bass, Adam, Ligon, Keith, Janeway, Katherine, Root, David, Schreiber, Stuart, Clemons, Paul, Golub, Todd, Hahn, William, Boehm, Jesse
Published in Molecular cancer therapeutics (01.10.2017)
Published in Molecular cancer therapeutics (01.10.2017)
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Journal Article
Abstract 1953: Accelerating prediction of pediatric and rare cancer vulnerabilities using next-generation cancer models
Tseng, Yuen-Yi, Hong, Andrew, Keskula, Paula, Gill, Shubhroz, Cheah, Jaime, Kryukov, Grigoriy, Tsherniak, Aviad, Vazquez, Francisca, Cowley, Glenn, Alkhairy, Sahar, Oh, Coyin, Peng, Anson, Deasy, Rebecca, Sayeed, Abeer, Ronning, Peter, Ng, Samuel, Corsello, Steven, Painter, Corrie, Sandak, David, Garraway, Levi, Rubin, Mark, Kuo, Calvin, Puram, Sidharth, Weinstock, David, Bass, Adam, Wagle, Nikhil, Ligon, Keith, Janeway, Katherine, Root, David, Schreiber, Stuart, Clemons, Paul, Shamji, Aly, Hahn, William, Golub, Todd, Boehm, Jesse
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract B13: Human pancreatic cancer organoids for functional dependency profiling
Raghavan, Srivatsan, Gill, Shubhroz, Aguirre, Andrew J., Tseng, Yuen-Yi M., Peng, Anson, Keskula, Paula, Wu, Xiaoyun, Oh, Coyin, Cheah, Jamie, Kryukov, Gregory, Sicinska, Ewa, Wolpin, Brian M., Kulke, Matthew H., Fuchs, Charles S., Clemons, Paul, Golub, Todd R., Schreiber, Stuart, Boehm, Jesse S., Hahn, William C.
Published in Clinical cancer research (15.08.2016)
Published in Clinical cancer research (15.08.2016)
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Journal Article
Abstract 4367: Accelerating prediction of tumor vulnerabilities using next-generation cancer models
Tseng, Yuen-Yi, Hong, Andrew, Keskula, Paula, Gill, Shubhroz, Cheah, Jaime, Kryukov, Grigoriy, Tsherniak, Aviad, Vazquez, Francisca, Cowley, Glenn, Oh, Coyin, Peng, Anson, Sayeed, Abeer, Deasy, Rebecca, Ronning, Peter, Kantoff, Philip, Garraway, Levi, Rubin, Mark, Kuo, Calvin, Puram, Sidharth, Gazdar, Adi, Dela Cruz, Filemon, Bass, Adam, Wagle, Nikhil, Ligon, Keith, Janeway, Katherine, Root, David, Schreiber, Stuart, Clemons, Paul, Shamji, Aly, Hahn, William, Golub, Todd, Boehm, Jesse S.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract B26: Accelerating prediction of tumor vulnerabilities using next-generation cancer models
Tseng, Yuen-Yi, Keskula, Paula, Hong, Andrew L., Gill, Shubhroz, Cheah, Jaime H., Kryukov, Gregory V., Tsherniak, Aviad, Vazquez, Francisca, Cowley, Glenn, Oh, Coyin, Peng, Anson, Sayeed, Abeer, Deasy, Rebecca, Ronning, Peter, Kantoff, Philip, Garraway, Levi, Rubin, Mark A., Kuo, Calvin, Puram, Sidharth, Gazdar, Adi, Cruz, Filemon S. Dela, Bass, Adam, Wagle, Nikhil, Ligon, Keith L., Janeway, Katherine, Root, David, Schreiber, Stuart L., Clemons, Paul A., Shamji, Aly, Hahn, William C., Golub, Todd R., Boehm, Jesse S.
Published in Clinical cancer research (15.08.2016)
Published in Clinical cancer research (15.08.2016)
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Journal Article
CYCLOPENTAIMIDAZOLONES FOR THE TREATMENT OF CANCER
Hua, Bruce, Gill, Shubhroz, Nag, Partha, Hahn, William, Clemons, Paul, Schreiber, Stuart, Raghavan, Srivatsan, Ng, Raymond
Year of Publication 24.12.2020
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Year of Publication 24.12.2020
Patent
CYCLOPENTAIMIDAZOLONES FOR THE TREATMENT OF CANCER
RAGHAVAN, Srivatsan, HUA, Bruce, GILL, Shubhroz, SCHREIBER, Stuart, CLEMONS, Paul, HAHN, William, NAG, Partha, NG, Raymond
Year of Publication 12.09.2019
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Year of Publication 12.09.2019
Patent