Redirecting the specificity of tripartite motif containing-21 scaffolds using a novel discovery and design approach
VanDyke, Derek, Xu, Linda, Sargunas, Paul R., Gilbreth, Ryan N., Baca, Manuel, Gao, Changshou, Hunt, James, Spangler, Jamie B.
Published in The Journal of biological chemistry (01.12.2023)
Published in The Journal of biological chemistry (01.12.2023)
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Journal Article
Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer
Zanvit, Peter, van Dyk, Dewald, Fazenbaker, Christine, McGlinchey, Kelly, Luo, Weichuan, Pezold, Jessica M, Meekin, John, Chang, Chien-Ying, Carrasco, Rosa A, Breen, Shannon, Cheung, Crystal Sao-Fong, Endlich-Frazier, Ariel, Clark, Benjamin, Chu, Nina J, Vantellini, Alessio, Martin, Philip L, Hoover, Clare E, Riley, Kenesha, Sweet, Steve M, Chain, David, Kim, Yeoun Jin, Tu, Eric, Harder, Nathalie, Phipps, Sandrina, Damschroder, Melissa, Gilbreth, Ryan N, Cobbold, Mark, Moody, Gordon, Bosco, Emily E
Published in The Journal of clinical investigation (15.11.2023)
Published in The Journal of clinical investigation (15.11.2023)
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Journal Article
Crystal structure of the human 4-1BB/4-1BBL complex
Gilbreth, Ryan N., Oganesyan, Vaheh Y., Amdouni, Hamza, Novarra, Shabazz, Grinberg, Luba, Barnes, Arnita, Baca, Manuel
Published in The Journal of biological chemistry (22.06.2018)
Published in The Journal of biological chemistry (22.06.2018)
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Journal Article
A Nanoparticle Platform To Evaluate Bioconjugation and Receptor-Mediated Cell Uptake Using Cross-Linked Polyion Complex Micelles Bearing Antibody Fragments
Florinas, Stelios, Liu, Marc, Fleming, Ryan, Van Vlerken-Ysla, Lilian, Ayriss, Joanne, Gilbreth, Ryan, Dimasi, Nazzareno, Gao, Changshou, Wu, Herren, Xu, Ze-Qi, Chen, Shaoyi, Dirisala, Anjaneyulu, Kataoka, Kazunori, Cabral, Horacio, Christie, R. James
Published in Biomacromolecules (09.05.2016)
Published in Biomacromolecules (09.05.2016)
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Journal Article
Lipid- and polyion complex-based micelles as agonist platforms for TNFR superfamily receptors
Gilbreth, Ryan N., Novarra, Shabazz, Wetzel, Leslie, Florinas, Stelios, Cabral, Horacio, Kataoka, Kazunori, Rios-Doria, Jonathan, Christie, Ronald J., Baca, Manuel
Published in Journal of controlled release (28.07.2016)
Published in Journal of controlled release (28.07.2016)
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Journal Article
A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein–Protein Interfaces
Gilbreth, Ryan N., Esaki, Kaori, Koide, Akiko, Sidhu, Sachdev S., Koide, Shohei
Published in Journal of molecular biology (29.08.2008)
Published in Journal of molecular biology (29.08.2008)
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Journal Article
Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design
Gilbreth, Ryan N, Truong, Khue, Madu, Ikenna, Koide, Akiko, Wojcik, John B, Li, Nan-Sheng, Piccirilli, Joseph A, Chen, Yuan, Koide, Shohei
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2011)
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Journal Article
The Q-cycle reviewed: How well does a monomeric mechanism of the bc1 complex account for the function of a dimeric complex?
Crofts, Antony R., Holland, J. Todd, Victoria, Doreen, Kolling, Derrick R.J., Dikanov, Sergei A., Gilbreth, Ryan, Lhee, Sangmoon, Kuras, Richard, Kuras, Mariana Guergova
Published in Biochimica et biophysica acta (01.07.2008)
Published in Biochimica et biophysica acta (01.07.2008)
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Journal Article
112 Rational design of chimeric antigen receptor T cells against glypican 3 decouples toxicity from therapeutic efficacy
Giardino, Letizia, Gilbreth, Ryan, Chen, Cui, Sult, Erin, Monks, Noel, Tammali, Ravinder, Chesebrough, Jon, Schifferli, Kevin, Chu, Nina, Tong, Jessica, Clarke, Lori, Gesse, Christina, Yao, Xiao-Tao, DaCosta, Karma, Vashisht, Kapil, Moody, Gordon
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
Rational design of TGFbRII dominant negative armored GPC3 CAR-T cells for the treatment of hepatocellular carcinoma
Merlino, Ashley, Tu, Eric, Overstreet, Michael, Gilbreth, Ryan, Clarke, Lori, Cobbold, Mark, Moody, Gordon, Giardino, Letizia, Chu, Nina
Published in The Journal of immunology (1950) (01.05.2023)
Published in The Journal of immunology (1950) (01.05.2023)
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Journal Article
Antitumor activity of AZD0754, a dnTGF[beta]RII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer
Zanvit, Peter, van Dyk, Dewald, Fazenbaker, Christine, McGlinchey, Kelly, Luo, Weichuan, Pezold, Jessica M, Meekin, John, Chang, Chien-ying, Carrasco, Rosa A, Breen, Shannon, Cheung, Crystal Sao-Fong, Endlich-Frazier, Ariel, Clark, Benjamin, Chu, Nina J, Vantellini, Alessio, Martin, Philip L, Hoover, Clare E, Riley, Kenesha, Sweet, Steve M, Chain, David, Kim, Yeoun Jin, Tu, Eric, Harder, Nathalie, Phipps, Sandrina, Damschroder, Melissa, Gilbreth, Ryan N, Cobbold, Mark, Moody, Gordon, Bosco, Emily E
Published in The Journal of clinical investigation (15.11.2023)
Published in The Journal of clinical investigation (15.11.2023)
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Journal Article
Rational design of chimeric antigen receptor T cells against glypican 3 decouples toxicity from therapeutic efficacy
Giardino Torchia, Maria Letizia, Gilbreth, Ryan, Merlino, Ashley, Sult, Erin, Monks, Noel, Chesebrough, Jon, Tammali, Ravinder, Chu, Nina, Tong, Jessica, Meekin, John, Schifferli, Kevin, Vashisht, Kapil, DaCosta, Karma, Clarke, Lori, Gesse, Christina, Yao, Xiao-Tao, Bridges, Courtney, Moody, Gordon
Published in Cytotherapy (Oxford, England) (01.07.2022)
Published in Cytotherapy (Oxford, England) (01.07.2022)
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Journal Article
키메라 항원 수용체로 암을 치료하기 위한 조성물 및 방법
GIARDINO TORCHIA MARIA LETIZIA, OVERSTREET MICHAEL GLEN, MOODY GORDON, GILBRETH RYAN
Year of Publication 09.01.2023
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Year of Publication 09.01.2023
Patent
키메라 항원 수용체로 암을 치료하는 조성물 및 방법
GIARDINO TORCHIA MARIA LETIZIA, OVERSTREET MICHAEL GLEN, MOODY GORDON, GILBRETH RYAN
Year of Publication 09.01.2023
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Year of Publication 09.01.2023
Patent
글리피칸 3을 표적으로 하는 키메라 항원 수용체로 암을 치료하는 조성물 및 방법
GIARDINO TORCHIA MARIA LETIZIA, MOODY GORDON, MUMM JOHN, GILBRETH RYAN, WANG QIONG
Year of Publication 29.08.2022
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Year of Publication 29.08.2022
Patent