Characterization of Glycosaminoglycan (GAG) Sulfatases from the Human Gut Symbiont Bacteroides thetaiotaomicron Reveals the First GAG-specific Bacterial Endosulfatase
Ulmer, Jonathan E., Vilén, Eric Morssing, Namburi, Ramesh Babu, Benjdia, Alhosna, Beneteau, Julie, Malleron, Annie, Bonnaffé, David, Driguez, Pierre-Alexandre, Descroix, Karine, Lassalle, Gilbert, Le Narvor, Christine, Sandström, Corine, Spillmann, Dorothe, Berteau, Olivier
Published in The Journal of biological chemistry (29.08.2014)
Published in The Journal of biological chemistry (29.08.2014)
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Journal Article
5‑Chlorothiophene-2-carboxylic Acid [(S)‑2-[2-Methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor
Meneyrol, Jerome, Follmann, Markus, Lassalle, Gilbert, Wehner, Volkmar, Barre, Guillaume, Rousseaux, Tristan, Altenburger, Jean-Michel, Petit, Frederic, Bocskei, Zsolt, Schreuder, Herman, Alet, Nathalie, Herault, Jean-Pascal, Millet, Laurence, Dol, Frederique, Florian, Peter, Schaeffer, Paul, Sadoun, Freddy, Klieber, Sylvie, Briot, Christophe, Bono, Françoise, Herbert, Jean-Marc
Published in Journal of medicinal chemistry (12.12.2013)
Published in Journal of medicinal chemistry (12.12.2013)
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Journal Article
SSR182289A, a selective and potent orally active thrombin inhibitor
Altenburger, Jean-Michel, Lassalle, Gilbert Y., Matrougui, Mostapha, Galtier, Daniel, Jetha, Jean-Claude, Bocskei, Zsolt, Berry, Christopher N., Lunven, Catherine, Lorrain, Janine, Herault, Jean-Pascal, Schaeffer, Paul, O'Connor, Stephen E., Herbert, Jean-Marc
Published in Bioorganic & medicinal chemistry (01.04.2004)
Published in Bioorganic & medicinal chemistry (01.04.2004)
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Journal Article
Influence of Heparin Mimetics on Assembly of the FGF·FGFR4 Signaling Complex
Saxena, Krishna, Schieborr, Ulrich, Anderka, Oliver, Duchardt-Ferner, Elke, Elshorst, Bettina, Gande, Santosh Lakshmi, Janzon, Julia, Kudlinzki, Denis, Sreeramulu, Sridhar, Dreyer, Matthias K., Wendt, K. Ulrich, Herbert, Corentin, Duchaussoy, Philippe, Bianciotto, Marc, Driguez, Pierre-Alexandre, Lassalle, Gilbert, Savi, Pierre, Mohammadi, Moosa, Bono, Françoise, Schwalbe, Harald
Published in The Journal of biological chemistry (20.08.2010)
Published in The Journal of biological chemistry (20.08.2010)
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Journal Article
SSR182289A, a Novel, Orally Active Thrombin Inhibitor: In Vitro Profile and ex Vivo Anticoagulant Activity
Berry, Christopher N, Lassalle, Gilbert, Lunven, Catherine, Altenburger, Jean-Michel, Guilbert, Frédérique, Lalé, Alain, Hérault, Jean-Pascal, Lecoffre, Catherine, Pfersdorff, Christian, Herbert, Jean-Marc, O'Connor, Stephen E
Published in The Journal of pharmacology and experimental therapeutics (01.12.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2002)
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Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling
Herbert, Corentin, Schieborr, Ulrich, Saxena, Krishna, Juraszek, Jarek, De Smet, Frederik, Alcouffe, Chantal, Bianciotto, Marc, Saladino, Giorgio, Sibrac, David, Kudlinzki, Denis, Sreeramulu, Sridhar, Brown, Alan, Rigon, Patrice, Herault, Jean-Pascal, Lassalle, Gilbert, Blundell, Tom L., Rousseau, Frederic, Gils, Ann, Schymkowitz, Joost, Tompa, Peter, Herbert, Jean-Marc, Carmeliet, Peter, Gervasio, Francesco Luigi, Schwalbe, Harald, Bono, Françoise
Published in Cancer cell (15.04.2013)
Published in Cancer cell (15.04.2013)
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European Medicinal Chemistry Leaders in Industry (EMCL) – On the Status and Future of Medicinal Chemistry Research in Europe
Ali, Amjad, Bauser, Marcus, Bertrand, Sophie, Blackaby, Wesley, Boss, Christoph, Bossart, Martin, Hall, Adrian, Binch, Hayley, Czechtizky, Werngard, Gijsen, Harrie, Haning, Helmut, Hartung, Ingo V., Kilburn, Paul, Lassalle, Gilbert, Lücking, Ulrich, Mack, Jürgen, Missbach, Martin, Otsomaa, Leena, Torrens, Antoni, Wagner, Michael, Walter, Magnus, Weinstabl, Harald, Hijfte, Luc, Nussbaum, Franz
Published in ChemMedChem (03.07.2023)
Published in ChemMedChem (03.07.2023)
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N‑[6-(4-Butanoyl-5-methyl‑1H‑pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]‑1H‑indole-3-carboxamide (SAR216471), a Novel Intravenous and Oral, Reversible, and Directly Acting P2Y12 Antagonist
Boldron, Christophe, Besse, Angélina, Bordes, Marie-Françoise, Tissandié, Stéphanie, Yvon, Xavier, Gau, Benjamin, Badorc, Alain, Rousseaux, Tristan, Barré, Guillaume, Meneyrol, Jérôme, Zech, Gernot, Nazare, Marc, Fossey, Valérie, Pflieger, Anne-Marie, Bonnet-Lignon, Sandrine, Millet, Laurence, Briot, Christophe, Dol, Frédérique, Hérault, Jean-Pascal, Savi, Pierre, Lassalle, Gilbert, Delesque, Nathalie, Herbert, Jean-Marc, Bono, Françoise
Published in Journal of medicinal chemistry (11.09.2014)
Published in Journal of medicinal chemistry (11.09.2014)
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Journal Article
N -[6-(4-Butanoyl-5-methyl-1 H -pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1 H -indole-3-carboxamide (SAR216471), a Novel Intravenous and Oral, Reversible, and Directly Acting P2Y12 Antagonist
Boldron, Christophe, Besse, Angélina, Bordes, Marie-Françoise, Tissandié, Stéphanie, Yvon, Xavier, Gau, Benjamin, Badorc, Alain, Rousseaux, Tristan, Barré, Guillaume, Meneyrol, Jérôme, Zech, Gernot, Nazare, Marc, Fossey, Valérie, Pflieger, Anne-Marie, Bonnet-Lignon, Sandrine, Millet, Laurence, Briot, Christophe, Dol, Frédérique, Hérault, Jean-Pascal, Savi, Pierre, Lassalle, Gilbert, Delesque, Nathalie, Herbert, Jean-Marc, Bono, Françoise
Published in Journal of medicinal chemistry (11.09.2014)
Published in Journal of medicinal chemistry (11.09.2014)
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Journal Article
Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling
Herbert, Corentin, Schieborr, Ulrich, Saxena, Krishna, Juraszek, Jarek, De Smet, Frederik, Alcouffe, Chantal, Bianciotto, Marc, Saladino, Giorgio, Sibrac, David, Kudlinzki, Denis, Sreeramulu, Sridhar, Brown, Alan, Rigon, Patrice, Herault, Jean-Pascal, Lassalle, Gilbert, Blundell, Tom L., Rousseau, Frederic, Gils, Ann, Schymkowitz, Joost, Tompa, Peter, Herbert, Jean-Marc, Carmeliet, Peter, Gervasio, Francesco Luigi, Schwalbe, Harald, Bono, Françoise
Published in Cancer cell (11.07.2016)
Published in Cancer cell (11.07.2016)
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Studies directed toward the total synthesis of cerorubenic acid-III. 2. Analysis of the inability to realize D ring formation by means of extraannular Robinson annulation
Paquette, Leo A, Lassalle, Gilbert Y, Lovely, Carl J
Published in Journal of organic chemistry (01.07.1993)
Published in Journal of organic chemistry (01.07.1993)
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Journal Article
Characterization of Gglycosaminoglycan (GAG) sulfatases from the human gut symbiont bacteroides thetaiotaomicron reveals the first GAG-specific bacterial endosulfatase
Ulmer, Jonathan, Vilen, Eric Morssing, Namburi, Ramesh Babu, Benjdia, Alhosna, Beneteau, Julie, Malleron, Annie, Bonnaffe, David, Driguez, Pierre-Alexandre, Descroix, Karine, Lassalle, Gilbert, Le Narvor, Christine, Sandstrom, Corine, Spillmann, Dorothe, Berteau, Olivier
Published in The Journal of biological chemistry (2014)
Published in The Journal of biological chemistry (2014)
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Journal Article
Phosphonium-ion tethered tetracycline drugs for treatment of cancer
Froidbise, Alexandre, Lassalle, Gilbert, Sparey, Tim, Cochrane, Edward, Hallett, David, Stevenson, Brett, Lagasse, Franz, Ratcliffe, Andrew
Year of Publication 02.11.2021
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Year of Publication 02.11.2021
Patent
Influence of heparin mimetics on assembly of the FGF.FGFR4 signaling complex
Saxena, Krishna, Schieborr, Ulrich, Anderka, Oliver, Duchardt-Ferner, Elke, Elshorst, Bettina, Gande, Santosh Lakshmi, Janzon, Julia, Kudlinzki, Denis, Sreeramulu, Sridhar, Dreyer, Matthias K, Wendt, K Ulrich, Herbert, Corentin, Duchaussoy, Philippe, Bianciotto, Marc, Driguez, Pierre-Alexandre, Lassalle, Gilbert, Savi, Pierre, Mohammadi, Moosa, Bono, Françoise, Schwalbe, Harald
Published in The Journal of biological chemistry (20.08.2010)
Published in The Journal of biological chemistry (20.08.2010)
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Journal Article
TRIPHENYLPHOSPHONIUM-TETHERED TETRACYCLINES FOR USE IN TREATING CANCER
Froidbise, Alexandre, Lassalle, Gilbert, Sparey, Tim, Cochrane, Edward, Hallett, David, Stevenson, Brett, Ratcliffe, Andrew
Year of Publication 30.04.2020
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Year of Publication 30.04.2020
Patent
PHOSPHONIUM-ION TETHERED TETRACYCLINE DRUGS FOR TREATMENT OF CANCER
Froidbise, Alexandre, Lassalle, Gilbert, Sparey, Tim, Cochrane, Edward, Hallett, David, Stevenson, Brett, Lagasse, Franz, Ratcliffe, Andrew
Year of Publication 23.04.2020
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Year of Publication 23.04.2020
Patent