Anti-trypanosomatid drug discovery: progress and challenges
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Published in Nature reviews. Microbiology (01.01.2023)
Published in Nature reviews. Microbiology (01.01.2023)
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Challenges and recent progress in drug discovery for tropical diseases
De Rycker, Manu, Baragaña, Beatriz, Duce, Suzanne L., Gilbert, Ian H.
Published in Nature (London) (01.07.2018)
Published in Nature (London) (01.07.2018)
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Characterising covalent warhead reactivity
Martin, James S., MacKenzie, Claire J., Fletcher, Daniel, Gilbert, Ian H.
Published in Bioorganic & medicinal chemistry (15.05.2019)
Published in Bioorganic & medicinal chemistry (15.05.2019)
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Towards the sustainable discovery and development of new antibiotics
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Published in Nature reviews. Chemistry (2021)
Published in Nature reviews. Chemistry (2021)
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Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need
Field, Mark C., Horn, David, Fairlamb, Alan H., Ferguson, Michael A. J., Gray, David W., Read, Kevin D., De Rycker, Manu, Torrie, Leah S., Wyatt, Paul G., Wyllie, Susan, Gilbert, Ian H.
Published in Nature reviews. Microbiology (01.04.2017)
Published in Nature reviews. Microbiology (01.04.2017)
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Partial Discharge Classification Using Deep Learning Methods—Survey of Recent Progress
Barrios, Sonia, Buldain, David, Comech, María Paz, Gilbert, Ian, Orue, Iñaki
Published in Energies (Basel) (27.06.2019)
Published in Energies (Basel) (27.06.2019)
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Clinical and veterinary trypanocidal benzoxaboroles target CPSF3
Wall, Richard J., Rico, Eva, Lukac, Iva, Zuccotto, Fabio, Elg, Sara, Gilbert, Ian H., Freund, Yvonne, Alley, M. R. K., Field, Mark C., Wyllie, Susan, Horn, David
Published in Proceedings of the National Academy of Sciences - PNAS (18.09.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (18.09.2018)
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Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
Baragan˜a, Beatriz, Forte, Barbara, Choi, Ryan, Hewitt, Stephen Nakazawa, Bueren-Calabuig, Juan A., Pisco, Joa˜o Pedro, Peet, Caroline, Dranow, David M., Robinson, David A., Jansen, Chimed, Norcross, Neil R., Vinayak, Sumiti, Anderson, Mark, Brooks, Carrie F., Cooper, Caitlin A., Damerow, Sebastian, Delves, Michael, Dowers, Karen, Duffy, James, Edwards, Thomas E., Hallyburton, Irene, Horst, Benjamin G., Hulverson, Matthew A., Ferguson, Liam, Jiménez-Díaz, María Belén, Jumani, Rajiv S., Lorimer, Donald D., Love, Melissa S., Maher, Steven, Matthews, Holly, McNamara, Case W., Miller, Peter, O’Neill, Sandra, Ojo, Kayode K., Osuna-Cabello, Maria, Pinto, Erika, Post, John, Riley, Jennifer, Rottmann, Matthias, Sanz, Laura M., Scullion, Paul, Sharma, Arvind, Shepherd, Sharon M., Shishikura, Yoko, Simeons, Frederick R. C., Stebbins, Erin E., Stojanovski, Laste, Straschil, Ursula, Tamaki, Fabio K., Tamjar, Jevgenia, Torrie, Leah S., Vantaux, Amélie, Witkowski, Benoît, Wittlin, Sergio, Yogavel, Manickam, Zuccotto, Fabio, Angulo-Barturen, Iñigo, Sinden, Robert, Baum, Jake, Gamo, Francisco-Javier, Mäser, Pascal, Kyle, Dennis E., Winzeler, Elizabeth A., Myler, Peter J., Wyatt, Paul G., Floyd, David, Matthews, David, Sharma, Amit, Striepen, Boris, Huston, Christopher D., Gray, David W., Fairlamb, Alan H., Pisliakov, Andrei V., Walpole, Chris, Read, Kevin D., Van Voorhis, Wesley C., Gilbert, Ian H.
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2019)
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Author Correction: Anti-trypanosomatid drug discovery: progress and challenges
De Rycker, Manu, Wyllie, Susan, Horn, David, Read, Kevin D., Gilbert, Ian H.
Published in Nature reviews. Microbiology (01.11.2022)
Published in Nature reviews. Microbiology (01.11.2022)
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Automated design of ligands to polypharmacological profiles
Besnard, Jérémy, Ruda, Gian Filippo, Setola, Vincent, Abecassis, Keren, Rodriguiz, Ramona M., Huang, Xi-Ping, Norval, Suzanne, Sassano, Maria F., Shin, Antony I., Webster, Lauren A., Simeons, Frederick R. C., Stojanovski, Laste, Prat, Annik, Seidah, Nabil G., Constam, Daniel B., Bickerton, G. Richard, Read, Kevin D., Wetsel, William C., Gilbert, Ian H., Roth, Bryan L., Hopkins, Andrew L.
Published in Nature (London) (13.12.2012)
Published in Nature (London) (13.12.2012)
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Design of the Global Health chemical diversity library v2 for screening against infectious diseases
Wilson, Caroline, Gardner, J Mark F, Gray, David W, Baragana, Beatriz, Wyatt, Paul G, Cookson, Alex, Thompson, Stephen, Mendoza-Martinez, Cesar, Bodkin, Michael J, Gilbert, Ian H, Tarver, Gary J
Published in PLoS neglected tropical diseases (01.12.2023)
Published in PLoS neglected tropical diseases (01.12.2023)
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Synthesis of a Series of Diaminoindoles
Martin, James S, Mackenzie, Claire J, Gilbert, Ian H
Published in Journal of organic chemistry (03.09.2021)
Published in Journal of organic chemistry (03.09.2021)
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Drug discovery research in Ghana, challenges, current efforts, and the way forward
Amewu, Richard Kwamla, Amoateng, Patrick, Arthur, Patrick Kobina, Asare, Prince, Asiamah, Isaac, Boamah, Daniel, Darko Otchere, Isaac, Dzidzor Amengor, Cedric, Ekuadzi, Edmund, Chibale, Kelly, Farrell, Susan Jane, Appiah-Oppong, Regina, Osei-Safo, Dorcas, David Read, Kevin, Hugh Gilbert, Ian, Yeboah-Manu, Dorothy
Published in PLoS neglected tropical diseases (01.09.2022)
Published in PLoS neglected tropical diseases (01.09.2022)
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High-Throughput Screening Platform To Identify Inhibitors of Protein Synthesis with Potential for the Treatment of Malaria
Tamaki, Fabio, Fisher, Fabio, Milne, Rachel, Terán, Fernando Sánchez-Román, Wiedemar, Natalie, Wrobel, Karolina, Edwards, Darren, Baumann, Hella, Gilbert, Ian H, Baragana, Beatriz, Baum, Jake, Wyllie, Susan
Published in Antimicrobial agents and chemotherapy (21.06.2022)
Published in Antimicrobial agents and chemotherapy (21.06.2022)
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Comparison of a High-Throughput High-Content Intracellular Leishmania donovani Assay with an Axenic Amastigote Assay
DE RYCKER, Manu, HALLYBURTON, Irene, FAIRLAMB, Alan H, GRAY, David W, THOMAS, John, CAMPBELL, Lorna, WYLLIE, Susan, JOSHI, Dhananjay, CAMERON, Scott, GILBERT, Ian H, WYATT, Paul G, FREARSON, Julie A
Published in Antimicrobial Agents and Chemotherapy (01.07.2013)
Published in Antimicrobial Agents and Chemotherapy (01.07.2013)
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DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis
Mowbray, Charles E, Braillard, Stéphanie, Glossop, Paul A, Whitlock, Gavin A, Jacobs, Robert T, Speake, Jason, Pandi, Bharathi, Nare, Bakela, Maes, Louis, Yardley, Vanessa, Freund, Yvonne, Wall, Richard J, Carvalho, Sandra, Bello, Davide, Van den Kerkhof, Magali, Caljon, Guy, Gilbert, Ian H, Corpas-Lopez, Victoriano, Lukac, Iva, Patterson, Stephen, Zuccotto, Fabio, Wyllie, Susan
Published in Journal of medicinal chemistry (11.11.2021)
Published in Journal of medicinal chemistry (11.11.2021)
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A novel multiple-stage antimalarial agent that inhibits protein synthesis
Baragaña, Beatriz, Hallyburton, Irene, Lee, Marcus C. S., Norcross, Neil R., Grimaldi, Raffaella, Otto, Thomas D., Proto, William R., Blagborough, Andrew M., Meister, Stephan, Wirjanata, Grennady, Ruecker, Andrea, Upton, Leanna M., Abraham, Tara S., Almeida, Mariana J., Pradhan, Anupam, Porzelle, Achim, Martínez, María Santos, Bolscher, Judith M., Woodland, Andrew, Luksch, Torsten, Norval, Suzanne, Zuccotto, Fabio, Thomas, John, Simeons, Frederick, Stojanovski, Laste, Osuna-Cabello, Maria, Brock, Paddy M., Churcher, Tom S., Sala, Katarzyna A., Zakutansky, Sara E., Jiménez-Díaz, María Belén, Sanz, Laura Maria, Riley, Jennifer, Basak, Rajshekhar, Campbell, Michael, Avery, Vicky M., Sauerwein, Robert W., Dechering, Koen J., Noviyanti, Rintis, Campo, Brice, Frearson, Julie A., Angulo-Barturen, Iñigo, Ferrer-Bazaga, Santiago, Gamo, Francisco Javier, Wyatt, Paul G., Leroy, Didier, Siegl, Peter, Delves, Michael J., Kyle, Dennis E., Wittlin, Sergio, Marfurt, Jutta, Price, Ric N., Sinden, Robert E., Winzeler, Elizabeth A., Charman, Susan A., Bebrevska, Lidiya, Gray, David W., Campbell, Simon, Fairlamb, Alan H., Willis, Paul A., Rayner, Julian C., Fidock, David A., Read, Kevin D., Gilbert, Ian H.
Published in Nature (London) (18.06.2015)
Published in Nature (London) (18.06.2015)
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