Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion
Blythe, Nicola M., Muraki, Katsuhiko, Ludlow, Melanie J., Stylianidis, Vasili, Gilbert, Hamish T.J., Evans, Elizabeth L., Cuthbertson, Kevin, Foster, Richard, Swift, Joe, Li, Jing, Drinkhill, Mark J., van Nieuwenhoven, Frans A., Porter, Karen E., Beech, David J., Turner, Neil A.
Published in The Journal of biological chemistry (15.11.2019)
Published in The Journal of biological chemistry (15.11.2019)
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Journal Article
An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness
Galarza Torre, Asier, Shaw, Joshua E., Wood, Amber, Gilbert, Hamish T. J., Dobre, Oana, Genever, Paul, Brennan, Keith, Richardson, Stephen M., Swift, Joe
Published in Scientific reports (12.06.2018)
Published in Scientific reports (12.06.2018)
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Journal Article
Transcriptomic profiling reveals key early response genes during GDF6‐mediated differentiation of human adipose‐derived stem cells to nucleus pulposus cells
Gilbert, Hamish T. J., Wignall, Francis E. J., Zeef, Leo, Hoyland, Judith A., Richardson, Stephen M.
Published in JOR-spine (01.03.2024)
Published in JOR-spine (01.03.2024)
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Journal Article
Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading
Gilbert, Hamish T. J., Mallikarjun, Venkatesh, Dobre, Oana, Jackson, Mark R., Pedley, Robert, Gilmore, Andrew P., Richardson, Stephen M., Swift, Joe
Published in Nature communications (12.09.2019)
Published in Nature communications (12.09.2019)
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Journal Article
Loss of regulation of protein synthesis and turnover underpins an attenuated stress response in senescent human mesenchymal stem cells
Llewellyn, Jack, Mallikarjun, Venkatesh, Appleton, Ellen, Osipova, Maria, Gilbert, Hamish T J, Richardson, Stephen M, Hubbard, Simon J, Swift, Joe
Published in Proceedings of the National Academy of Sciences - PNAS (04.04.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (04.04.2023)
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Journal Article
In situ-forming robust chitosan-poly(ethylene glycol) hydrogels prepared by copper-free azide–alkyne click reaction for tissue engineering
Truong, Vinh X., Ablett, Matthew P., Gilbert, Hamish T. J., Bowen, James, Richardson, Stephen M., Hoyland, Judith A., Dove, Andrew P.
Published in Biomaterials science (01.01.2014)
Published in Biomaterials science (01.01.2014)
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Journal Article
Integrin - dependent mechanotransduction in mechanically stimulated human annulus fibrosus cells: evidence for an alternative mechanotransduction pathway operating with degeneration
Gilbert, Hamish T J, Nagra, Navraj S, Freemont, Anthony J, Millward-Sadler, Sarah J, Hoyland, Judith A
Published in PloS one (05.09.2013)
Published in PloS one (05.09.2013)
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Journal Article
Stem Cell Regeneration of Degenerated Intervertebral Discs: Current Status (Update)
Gilbert, Hamish T. J., Hoyland, Judith A., Richardson, Stephen M.
Published in Current pain and headache reports (01.12.2013)
Published in Current pain and headache reports (01.12.2013)
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Journal Article
Fabrication of 3‑Dimensional Cellular Constructs via Microstereolithography Using a Simple, Three-Component, Poly(Ethylene Glycol) Acrylate-Based System
Leigh, Simon J, Gilbert, Hamish T. J, Barker, Ian A, Becker, Jan M, Richardson, Stephen M, Hoyland, Judith A, Covington, James A, Dove, Andrew P
Published in Biomacromolecules (14.01.2013)
Published in Biomacromolecules (14.01.2013)
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Journal Article
The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with degeneration
Gilbert, Hamish T J, Hoyland, Judith A, Freemont, Anthony J, Millward-Sadler, Sarah J
Published in Arthritis research & therapy (28.01.2011)
Published in Arthritis research & therapy (28.01.2011)
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Journal Article
A microstereolithography resin based on thiol-ene chemistry: towards biocompatible 3D extracellular constructs for tissue engineering
Barker, Ian A., Ablett, Matthew P., Gilbert, Hamish T. J., Leigh, Simon J., Covington, James A., Hoyland, Judith A., Richardson, Stephen M., Dove, Andrew P.
Published in Biomaterials science (01.01.2014)
Published in Biomaterials science (01.01.2014)
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Journal Article