Highly Promiscuous Small Molecules from Biological Screening Assays Include Many Pan-Assay Interference Compounds but Also Candidates for Polypharmacology
Gilberg, Erik, Jasial, Swarit, Stumpfe, Dagmar, Dimova, Dilyana, Bajorath, Jürgen
Published in Journal of medicinal chemistry (23.11.2016)
Published in Journal of medicinal chemistry (23.11.2016)
Get full text
Journal Article
Mapping the S1 and S1' subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents
Cianni, Lorenzo, Lemke, Carina, Gilberg, Erik, Feldmann, Christian, Rosini, Fabiana, Rocho, Fernanda Dos Reis, Ribeiro, Jean F R, Tezuka, Daiane Y, Lopes, Carla D, de Albuquerque, Sérgio, Bajorath, Jürgen, Laufer, Stefan, Leitão, Andrei, Gütschow, Michael, Montanari, Carlos A
Published in PLoS neglected tropical diseases (01.03.2020)
Published in PLoS neglected tropical diseases (01.03.2020)
Get full text
Journal Article
How Significant Are Unusual Protein–Ligand Interactions? Insights from Database Mining
Kuhn, Bernd, Gilberg, Erik, Taylor, Robin, Cole, Jason, Korb, Oliver
Published in Journal of medicinal chemistry (27.11.2019)
Published in Journal of medicinal chemistry (27.11.2019)
Get full text
Journal Article
Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity?
Cianni, Lorenzo, Feldmann, Christian Wolfgang, Gilberg, Erik, Gütschow, Michael, Juliano, Luiz, Leitão, Andrei, Bajorath, Jürgen, Montanari, Carlos A
Published in Journal of medicinal chemistry (12.12.2019)
Published in Journal of medicinal chemistry (12.12.2019)
Get full text
Journal Article
X‑ray Structures of Target–Ligand Complexes Containing Compounds with Assay Interference Potential
Gilberg, Erik, Gütschow, Michael, Bajorath, Jürgen
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
Get full text
Journal Article
Cathepsin B: Active site mapping with peptidic substrates and inhibitors
Schmitz, Janina, Gilberg, Erik, Löser, Reik, Bajorath, Jürgen, Bartz, Ulrike, Gütschow, Michael
Published in Bioorganic & medicinal chemistry (01.01.2019)
Published in Bioorganic & medicinal chemistry (01.01.2019)
Get full text
Journal Article
치환된 이속사졸린 유도체
HUWYLER NIKOLAS, GILBERG ERIK, SAMBASIVAN SUNDERRAMAN, KOERBER KARSTEN
Year of Publication 17.10.2023
Get full text
Year of Publication 17.10.2023
Patent
Design of an Activity-Based Probe for Human Neutrophil Elastase: Implementation of the Lossen Rearrangement To Induce Förster Resonance Energy Transfers
Schulz-Fincke, Anna-Christina, Tikhomirov, Alexander S, Braune, Annett, Girbl, Tamara, Gilberg, Erik, Bajorath, Jürgen, Blaut, Michael, Nourshargh, Sussan, Gütschow, Michael
Published in Biochemistry (Easton) (06.02.2018)
Published in Biochemistry (Easton) (06.02.2018)
Get full text
Journal Article
N-Sulfonyl dipeptide nitriles as inhibitors of human cathepsin S: In silico design, synthesis and biochemical characterization
Lemke, Carina, Cianni, Lorenzo, Feldmann, Christian, Gilberg, Erik, Yin, Jiafei, dos Reis Rocho, Fernanda, de Vita, Daniela, Bartz, Ulrike, Bajorath, Jürgen, Montanari, Carlos A., Gütschow, Michael
Published in Bioorganic & medicinal chemistry letters (15.09.2020)
Published in Bioorganic & medicinal chemistry letters (15.09.2020)
Get full text
Journal Article