Novel 2,7-Diazaspiro[4,4]nonane Derivatives to Inhibit Mouse and Human Osteoclast Activities and Prevent Bone Loss in Ovariectomized Mice without Affecting Bone Formation
Mounier, Lucile, Morel, Anne, Ferrandez, Yann, Morko, Jukka, Vääräniemi, Jukka, Gilardone, Marine, Roche, Didier, Cherfils, Jacqueline, Blangy, Anne
Published in Journal of medicinal chemistry (25.11.2020)
Published in Journal of medicinal chemistry (25.11.2020)
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Journal Article
Discovery of novel Cyclophilin D inhibitors starting from three dimensional fragments with millimolar potencies
Grädler, Ulrich, Schwarz, Daniel, Blaesse, Michael, Leuthner, Birgitta, Johnson, Theresa L., Bernard, Frederic, Jiang, Xuliang, Marx, Andreas, Gilardone, Marine, Lemoine, Hugues, Roche, Didier, Jorand-Lebrun, Catherine
Published in Bioorganic & medicinal chemistry letters (01.12.2019)
Published in Bioorganic & medicinal chemistry letters (01.12.2019)
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Journal Article
A FARNESOID X RECEPTOR AGONSITS FORUSE AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CHRONIC HEPATITIS B VIRUS INFECTION
ROCHE, Didier, ANDRE, Patrice, HALLAKOU-BOZEC, Sophie, RADREAU, Pauline, GILARDONE, Marine, CRAVO, Daniel, PATIN, Amaury, LOTTEAU, Vincent
Year of Publication 23.09.2020
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Year of Publication 23.09.2020
Patent
COMPOUNDS FOR THE INHIBITION OF CYCLOPHILINS AND USES THEREOF
ROCHE, Didier, JIANG, Xuliang, GILARDONE, Marine, JORAND-LEBRUN, Catherine, LEMOINE, Hugues, GRAEDLER, Ulrich, JOHNSON, Theresa L
Year of Publication 06.02.2019
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Year of Publication 06.02.2019
Patent
COMPOUNDS FOR THE INHIBITION OF CYCLOPHILINS AND USES THEREOF
ROCHE, Didier, JIANG, Xuliang, GILARDONE, Marine, JORAND-LEBRUN, Catherine, LEMOINE, Hugues, GRAEDLER, Ulrich, JOHNSON, Theresa L
Year of Publication 06.02.2019
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Year of Publication 06.02.2019
Patent
Oxalyl derivatives and their use as cyclophilin inhibitors
GRAEDLER Ulrich, JORAND-LEBRUN Catherine, JOHNSON Theresa L, JIANG Xuliang, GILARDONE Marine, ROCHE Didier, LEMOINE Hugues
Year of Publication 31.10.2018
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Year of Publication 31.10.2018
Patent
Urea and amide derivatives and their use as cyclophilin inhibitors
GRAEDLER Ulrich, JORAND-LEBRUN Catherine, JOHNSON Theresa L, JIANG Xuliang, GILARDONE Marine, ROCHE Didier, LEMOINE Hugues
Year of Publication 31.10.2018
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Year of Publication 31.10.2018
Patent
Compounds for the inhibition of cyclophilins and uses thereof
Johnson, Theresa L, Jiang, Xuliang, Jorand-Lebrun, Catherine, Lemoine, Hugues, Gilardone, Marine, Graedler, Ulrich, Roche, Didier
Year of Publication 13.09.2018
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Year of Publication 13.09.2018
Patent
Compounds for the inhibition of cyclophilins and uses thereof
Johnson, Theresa L, Jiang, Xuliang, Jorand-Lebrun, Catherine, Lemoine, Hugues, Gilardone, Marine, Graedler, Ulrich, Roche, Didier
Year of Publication 13.09.2018
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Year of Publication 13.09.2018
Patent