Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function
Haines, Christopher J, Giffon, Thierry D, Lu, Li-Sheng, Lu, Xiaowei, Tessier-Lavigne, Marc, Ross, Douglas T, Lewis, David B
Published in The Journal of experimental medicine (16.02.2009)
Published in The Journal of experimental medicine (16.02.2009)
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711 IGM-7354 is an anti-PD-L1 IgM antibody and IL-15 cytokine fusion that enhances NK and CD8+ T cell proliferation and tumor cytotoxicity plus potently reverses T cell exhaustion
Giffon, Thierry, Desbois, Melanie, Ng, Dean, Yakkundi, Poonam, Manlusoc, Marigold, Oyasu, Miho, Rosete, Rodnie, Machado, Daniel, Calhoun, Susan, Kothambawala, Tasnim, Saini, Avneesh, Wang, Beatrice, Kotturi, Maya, Keyt, Bruce, Sinclair, Angus
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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569 Targeting IL-15 delivery to PD-L1 expressing tumors with an Anti-PD-L1-IL-15 cytokine fusion IgM to enhance T Cell and NK Cell Mediated tumor cytotoxicity
Sinclair, Angus, Giffon, Thierry, Ng, Dean, Yakkundi, Poonam, Lancero, Hope, Manlusoc, Marigold, Rosete, Rodnie, Saini, Avneesh, Tran, Madeline, Carlin, Kevin, Saraiya, Chitra, Baliga, Ramesh, Keyt, Bruce
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Influenza A virus elevates active cathepsin B in primary murine DC
Burster, Timo, Giffon, Thierry, Dahl, Martin E., Björck, Pia, Bogyo, Matthew, Weber, Ekkehard, Mahmood, Kutubuddin, Lewis, David B., Mellins, Elizabeth D.
Published in International immunology (01.05.2007)
Published in International immunology (01.05.2007)
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Abstract 3438: Enhanced NK and CD8+ T cell proliferation, tumor cytotoxicity and reversal of T cell exhaustion with IGM-7354, an anti-PD-L1 IgM antibody and IL-15 cytokine fusion
Giffon, Thierry, Desbois, Melanie, Yakkundi, Poonam, Sekar, Keerthana, Manlusoc, Marigold, Rosete, Rodnie, Machado, Daniel, Calhoun, Susan, Kothambawala, Tasnim, Ng, Dean, Tran, Vu, Saini, Avneesh, Jain, Abhinav, Wang, Beatrice, Kotturi, Maya, Keyt, Bruce, Sinclair, Angus
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 5660: IGM-7354, an immunocytokine with IL-15 fused to an anti-PD-L1 IgM, induces NK and CD8+ T cell mediated cytotoxicity of PD-L1-positive tumor cells
Giffon, Thierry D., Desbois, Melanie, Yakkundi, Poonam, Calhoun, Susan, Sekar, Keerthana, Denson, Carolyn, Kothambawala, Tasnim, Pearson, Alexander, Pandey, Sivani, Pandya, Deepal, Rosete, Rodnie, Machado, Daniel, Raichlen, Pat, Ng, Dean, Jain, Abhinav R., Funke, Roel, Humke, Eric, Hinton, Paul R., Wang, Beatrice, Keyt, Bruce A., Kotturi, Maya F., Sinclair, Angus M.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Enhanced in vivo immunity and protection provided by cationic lipid-DNA complex adjuvanted influenza vaccination is independent of Toll-like receptor 9 (106.16)
Botham, Crystal, Hong, David, Giffon, Thierry, Draghi, Monia, Fairman, Jeff, Lewis, David
Published in The Journal of immunology (1950) (01.04.2011)
Published in The Journal of immunology (1950) (01.04.2011)
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Abstract A21: Active immunotherapy with PROSTVAC® demonstrates potent antitumor efficacy in a mouse model of prostate cancer
Rountree, Ryan B., Mandl, Stefanie J., Cote, Joseph, Cruz, Tracy dela, Giffon, Thierry, Gordon, Evan, Foy, Susan P., Lombardo, John R., Trent, Erica, Laus, Reiner, Delcayre, Alain
Published in Cancer research (Chicago, Ill.) (01.01.2013)
Published in Cancer research (Chicago, Ill.) (01.01.2013)
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Immunotherapy with MVA-BN®-HER2 induces HER-2-specific Th1 immunity and alters the intratumoral balance of effector and regulatory T cells
Mandl, Stefanie J., Rountree, Ryan B., Dalpozzo, Katie, Do, Lisa, Lombardo, John R., Schoonmaker, Peter L., Dirmeier, Ulrike, Steigerwald, Robin, Giffon, Thierry, Laus, Reiner, Delcayre, Alain
Published in Cancer Immunology, Immunotherapy (01.01.2012)
Published in Cancer Immunology, Immunotherapy (01.01.2012)
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Impaired Accumulation and Function of Memory CD4 T Cells in Human IL-12 Receptor β1 Deficiency
Cleary, Aileen M., Tu, Wenwei, Enright, Andrea, Giffon, Thierry, Dewaal-Malefyt, Rene, Gutierrez, Kathleen, Lewis, David B.
Published in The Journal of immunology (1950) (01.01.2003)
Published in The Journal of immunology (1950) (01.01.2003)
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Immunotherapy with MVA-BN^sup ?^-HER2 induces HER-2-specific Th1 immunity and alters the intratumoral balance of effector and regulatory T cells
Mandl, Stefanie J, Rountree, Ryan B, Dalpozzo, Katie, Do, Lisa, Lombardo, John R, Schoonmaker, Peter L, Dirmeier, Ulrike, Steigerwald, Robin, Giffon, Thierry, Laus, Reiner, Delcayre, Alain
Published in Cancer immunology, immunotherapy (01.01.2012)
Published in Cancer immunology, immunotherapy (01.01.2012)
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Immunotherapy with MVA-BN super( registered )-HER2 induces HER-2-specific Th1 immunity and alters the intratumoral balance of effector and regulatory T cells
Mandl, Stefanie J, Rountree, Ryan B, Dalpozzo, Katie, Do, Lisa, Lombardo, John R, Schoonmaker, Peter L, Dirmeier, Ulrike, Steigerwald, Robin, Giffon, Thierry, Laus, Reiner, Delcayre, Alain
Published in Cancer Immunology, Immunotherapy (01.01.2012)
Published in Cancer Immunology, Immunotherapy (01.01.2012)
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Impaired accumulation and function of memory CD4 T cells in human IL-12 receptor beta 1 deficiency
Cleary, Aileen M, Tu, Wenwei, Enright, Andrea, Giffon, Thierry, Dewaal-Malefyt, Rene, Gutierrez, Kathleen, Lewis, David B
Published in The Journal of immunology (1950) (01.01.2003)
Published in The Journal of immunology (1950) (01.01.2003)
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