Search Results - "Giersbergen, Paul L. M." :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

First‐in‐man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials

by Moehrle, Joerg J., Duparc, Stephan, Siethoff, Christoph, Giersbergen, Paul L. M., Craft, J. Carl, Arbe‐Barnes, Sarah, Charman, Susan A., Gutierrez, Maria, Wittlin, Sergio, Vennerstrom, Jonathan L.
Published in British journal of clinical pharmacology (01.02.2013)

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Macitentan: entry-into-humans study with a new endothelin receptor antagonist

Macitentan: entry-into-humans study with a new endothelin receptor antagonist

by Sidharta, Patricia N., van Giersbergen, Paul L. M., Halabi, Atef, Dingemanse, Jasper
Published in European journal of clinical pharmacology (01.10.2011)

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Safety, tolerability, pharmacokinetics, and pharmacodynamics of macitentan, an endothelin receptor antagonist, in an ascending multiple-dose study in healthy subjects

Safety, tolerability, pharmacokinetics, and pharmacodynamics of macitentan, an endothelin receptor antagonist, in an ascending multiple-dose study in healthy subjects

by Sidharta, Patricia N, van Giersbergen, Paul L M, Dingemanse, Jasper
Published in Journal of clinical pharmacology (01.11.2013)

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Investigation of mutual pharmacokinetic interactions between macitentan, a novel endothelin receptor antagonist, and sildenafil in healthy subjects

Investigation of mutual pharmacokinetic interactions between macitentan, a novel endothelin receptor antagonist, and sildenafil in healthy subjects

by Sidharta, Patricia N., Giersbergen, Paul L. M., Wolzt, Michael, Dingemanse, Jasper
Published in British journal of clinical pharmacology (01.11.2014)

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Hemodynamics and pharmacokinetics of tezosentan, a dual endothelin receptor antagonist, in patients with cirrhosis

Hemodynamics and pharmacokinetics of tezosentan, a dual endothelin receptor antagonist, in patients with cirrhosis

by Lebrec, Didier, Bosch, Jaime, Jalan, Rajiv, Dudley, Francis J., Jessic, Rada, Moreau, Richard, Garcia-Pagan, Juan Carlos, Mookerjee, Rajeshwar P., Chiossi, Eleonora, Van Giersbergen, Paul L. M., Kusic-Pajic, Andjela, Dingemanse, Jasper
Published in European journal of clinical pharmacology (01.05.2012)

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Pharmacokinetics and pharmacodynamics of the urotensin-II receptor antagonist palosuran in healthy male subjects

Pharmacokinetics and pharmacodynamics of the urotensin-II receptor antagonist palosuran in healthy male subjects

by Sidharta, Patricia N, van Giersbergen, Paul L M, Dingemanse, Jasper
Published in Journal of clinical pharmacology (01.10.2009)

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Influence of Food Intake on the Pharmacokinetics of Miglustat, an Inhibitor of Glucosylceramide Synthase

Influence of Food Intake on the Pharmacokinetics of Miglustat, an Inhibitor of Glucosylceramide Synthase

by Giersbergen, Paul L. M., Dingemanse, Jasper
Published in Journal of clinical pharmacology (01.10.2007)

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Tolerability, pharmacokinetics, and pharmacodynamics of clazosentan, a parenteral endothelin receptor antagonist

Tolerability, pharmacokinetics, and pharmacodynamics of clazosentan, a parenteral endothelin receptor antagonist

by VAN GIERSBERGEN, Paul L. M, DINGEMANSE, Jasper
Published in European journal of clinical pharmacology (01.02.2007)

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Pharmacokinetics, safety, and efficacy of bosentan in pediatric patients with pulmonary arterial hypertension

Pharmacokinetics, safety, and efficacy of bosentan in pediatric patients with pulmonary arterial hypertension

by Barst, Robyn J, Ivy, Dunbar, Dingemanse, Jasper, Widlitz, Allison, Schmitt, Kelly, Doran, Aimee, Bingaman, Deborah, Nguyen, Ngoc, Gaitonde, Michael, van Giersbergen, Paul L M
Published in Clinical pharmacology and therapeutics (01.04.2003)

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In vivo and in vitro studies exploring the pharmacokinetic interaction between bosentan, a dual endothelin receptor antagonist, and glyburide

In vivo and in vitro studies exploring the pharmacokinetic interaction between bosentan, a dual endothelin receptor antagonist, and glyburide

by van Giersbergen, Paul L M, Treiber, Alexander, Clozel, Martine, Bodin, Frédéric, Dingemanse, Jasper
Published in Clinical pharmacology and therapeutics (01.04.2002)

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Influence of ethnic origin and sex on the pharmacokinetics of clazosentan

Influence of ethnic origin and sex on the pharmacokinetics of clazosentan

by van Giersbergen, Paul L M, Gunawardena, Kulasiri A, Dingemanse, Jasper
Published in Journal of clinical pharmacology (01.11.2007)

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Influence of mild liver impairment on the pharmacokinetics and metabolism of bosentan, a dual endothelin receptor antagonist

Influence of mild liver impairment on the pharmacokinetics and metabolism of bosentan, a dual endothelin receptor antagonist

by van Giersbergen, Paul L M, Popescu, Gabriela, Bodin, Frédéric, Dingemanse, Jasper
Published in Journal of clinical pharmacology (01.01.2003)

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Influence of liver cirrhosis on the pharmacokinetics, pharmacodynamics, and safety of tezosentan

Influence of liver cirrhosis on the pharmacokinetics, pharmacodynamics, and safety of tezosentan

by Dingemanse, Jasper, Halabi, Atef, van Giersbergen, Paul L M
Published in Journal of clinical pharmacology (01.04.2009)

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Clinical pharmacology of bosentan, a dual endothelin receptor antagonist

Clinical pharmacology of bosentan, a dual endothelin receptor antagonist

by DINGEMANSE, Jasper, VAN GIERSBERGEN, Paul L. M
Published in Clinical pharmacokinetics (01.01.2004)

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Comparative Investigation of the Pharmacokinetics of Bosentan in Caucasian and Japanese Healthy Subjects

Comparative Investigation of the Pharmacokinetics of Bosentan in Caucasian and Japanese Healthy Subjects

by Giersbergen, Paul L. M., Dingemanse, Jasper
Published in Journal of clinical pharmacology (01.01.2005)

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Single‐ and multiple‐dose pharmacokinetics of bosentan and its interaction with ketoconazole

Single‐ and multiple‐dose pharmacokinetics of bosentan and its interaction with ketoconazole

by van Giersbergen, Paul L. M., Halabi, Atef, Dingemanse, Jasper
Published in British journal of clinical pharmacology (01.06.2002)

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Pharmacokinetics, safety and tolerability of miglustat in the treatment of pediatric patients with GM2 gangliosidosis

Pharmacokinetics, safety and tolerability of miglustat in the treatment of pediatric patients with GM2 gangliosidosis

by Maegawa, Gustavo H.B., van Giersbergen, Paul L.M., Yang, Sandra, Banwell, Brenda, Morgan, Christopher P., Dingemanse, Jasper, Tifft, Cynthia J., Clarke, Joe T.R.
Published in Molecular genetics and metabolism (01.08.2009)

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Pharmacokinetics and pharmacodynamics of tezosentan, an intravenous dual endothelin receptor antagonist, following chronic infusion in healthy subjects

Pharmacokinetics and pharmacodynamics of tezosentan, an intravenous dual endothelin receptor antagonist, following chronic infusion in healthy subjects

by Dingemanse, Jasper, Clozel, Martine, Van Giersbergen, Paul L. M.
Published in British journal of clinical pharmacology (01.04.2002)

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Comparison of the pharmacokinetics, pharmacodynamics and tolerability of tezosentan between caucasian and Japanese subjects

Comparison of the pharmacokinetics, pharmacodynamics and tolerability of tezosentan between caucasian and Japanese subjects

by Dingemanse, Jasper, Gunawardena, Kulasiri A., van Giersbergen, Paul L. M.
Published in British journal of clinical pharmacology (01.04.2006)

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Influence of mild liver impairment on the pharmacokinetics of tezosentan, a drug excreted unchanged into bile

Influence of mild liver impairment on the pharmacokinetics of tezosentan, a drug excreted unchanged into bile

by Dingemanse, Jasper, Van Giersbergen, Paul L. M.
Published in British journal of clinical pharmacology (01.03.2004)

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