Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a Selective Inhibitor of Phosphodiesterase 7: In Vitro Studies in Human Monocytes, Lung Macrophages, and CD8+ T-Lymphocytes
Smith, Susan J, Cieslinski, Lenora B, Newton, Robert, Donnelly, Louise E, Fenwick, Peter S, Nicholson, Andrew G, Barnes, Peter J, Barnette, Mary S, Giembycz, Mark A
Published in Molecular pharmacology (01.12.2004)
Published in Molecular pharmacology (01.12.2004)
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Characterization of the prostanoid receptor(s) on human blood monocytes at which prostaglandin E 2 inhibits lipopolysaccharide‐induced tumour necrosis factor‐ α generation
Meja, Koremu K., Barnes, Peter J., Giembycz, Mark A.
Published in British journal of pharmacology (03.02.2009)
Published in British journal of pharmacology (03.02.2009)
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Enhancement of inflammatory mediator release by β 2 ‐adrenoceptor agonists in airway epithelial cells is reversed by glucocorticoid action
Holden, NS, Rider, CF, Bell, MJ, Velayudhan, J, King, EM, Kaur, M, Salmon, M, Giembycz, MA, Newton, R
Published in British journal of pharmacology (01.05.2010)
Published in British journal of pharmacology (01.05.2010)
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Delayed eosinophil apoptosis in asthma
Kankaanranta, Hannu, Lindsay, Mark A., Giembycz, Mark A., Zhang, Xianzhi, Moilanen, Eeva, Barnes, Peter J.
Published in Journal of allergy and clinical immunology (01.07.2000)
Published in Journal of allergy and clinical immunology (01.07.2000)
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Ubiquitous expression of phosphodiesterase 7A in human proinflammatory and immune cells
Smith, Susan J, Brookes-Fazakerley, Steven, Donnelly, Louise E, Barnes, Peter J, Barnette, Mary S, Giembycz, Mark A
Published in American journal of physiology. Lung cellular and molecular physiology (01.02.2003)
Published in American journal of physiology. Lung cellular and molecular physiology (01.02.2003)
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Enhancement of inflammatory mediator release by [beta]2-adrenoceptor agonists in airway epithelial cells is reversed by glucocorticoid action
Holden, NS, Rider, CF, Bell, MJ, Velayudhan, J, King, EM, Kaur, M, Salmon, M, Giembycz, MA, Newton, R
Published in British journal of pharmacology (01.05.2010)
Published in British journal of pharmacology (01.05.2010)
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E‐Ring 8‐isoprostanes inhibit ACh release from parasympathetic nerves innervating guinea‐pig trachea through agonism of prostanoid receptors of the EP3‐subtype
Clarke, Deborah L, Giembycz, Mark A, Patel, Hema J, Belvisi, Maria G
Published in British journal of pharmacology (01.02.2004)
Published in British journal of pharmacology (01.02.2004)
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Identification of cyclic AMP phosphodiesterases 3, 4 and 7 in human CD4+ and CD8+ T‐lymphocytes: role in regulating proliferation and the biosynthesis of interleukin‐2
Giembycz, Mark A., Corrigan, Christopher J., Seybold, Joachim, Newton, Robert, Barnes, Peter J.
Published in British journal of pharmacology (01.08.1996)
Published in British journal of pharmacology (01.08.1996)
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