Search Results - "Gielen, Heike" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of BAY 94-8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases

Discovery of BAY 94-8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases

by Bärfacker, Lars, Kuhl, Alexander, Hillisch, Alexander, Grosser, Rolf, Figueroa-Pérez, Santiago, Heckroth, Heike, Nitsche, Adam, Ergüden, Jens-Kerim, Gielen-Haertwig, Heike, Schlemmer, Karl-Heinz, Mittendorf, Joachim, Paulsen, Holger, Platzek, Johannes, Kolkhof, Peter
Published in ChemMedChem (01.08.2012)

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Journal Article

Synthesis of chiral triazolinylidene and imidazolinylidene transition metal complexes and first application in asymmetric catalysis

Synthesis of chiral triazolinylidene and imidazolinylidene transition metal complexes and first application in asymmetric catalysis

by Enders, Dieter, Gielen, Heike
Published in Journal of Organometallic Chemistry (01.01.2001)

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Book Review Journal Article

Diastereoselective Synthesis of Chiral (Triazolinylidene)rhodium Complexes Containing an Axis of Chirality

Diastereoselective Synthesis of Chiral (Triazolinylidene)rhodium Complexes Containing an Axis of Chirality

by Enders, Dieter, Gielen, Heike, Runsink, Jan, Breuer, Klaus, Brode, Stefan, Boehn, Karlheinz
Published in European journal of inorganic chemistry (01.07.1998)

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Journal Article

Cover Picture: Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases (ChemMedChem 7/2015)

Cover Picture: Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases (ChemMedChem 7/2015)

by von Nussbaum, Franz, Li, Volkhart M.-J., Allerheiligen, Swen, Anlauf, Sonja, Bärfacker, Lars, Bechem, Martin, Delbeck, Martina, Fitzgerald, Mary F., Gerisch, Michael, Gielen-Haertwig, Heike, Haning, Helmut, Karthaus, Dagmar, Lang, Dieter, Lustig, Klemens, Meibom, Daniel, Mittendorf, Joachim, Rosentreter, Ulrich, Schäfer, Martina, Schäfer, Stefan, Schamberger, Jens, Telan, Leila A., Tersteegen, Adrian
Published in ChemMedChem (01.07.2015)

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Journal Article

Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases

Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases

by von Nussbaum, Franz, Li, Volkhart M.-J., Allerheiligen, Swen, Anlauf, Sonja, Bärfacker, Lars, Bechem, Martin, Delbeck, Martina, Fitzgerald, Mary F., Gerisch, Michael, Gielen-Haertwig, Heike, Haning, Helmut, Karthaus, Dagmar, Lang, Dieter, Lustig, Klemens, Meibom, Daniel, Mittendorf, Joachim, Rosentreter, Ulrich, Schäfer, Martina, Schäfer, Stefan, Schamberger, Jens, Telan, Leila A., Tersteegen, Adrian
Published in ChemMedChem (01.07.2015)

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Journal Article

Cover Picture: Discovery of BAY 94-8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases (ChemMedChem 8/2012)

Cover Picture: Discovery of BAY 94-8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases (ChemMedChem 8/2012)

by Bärfacker, Lars, Kuhl, Alexander, Hillisch, Alexander, Grosser, Rolf, Figueroa-Pérez, Santiago, Heckroth, Heike, Nitsche, Adam, Ergüden, Jens-Kerim, Gielen-Haertwig, Heike, Schlemmer, Karl-Heinz, Mittendorf, Joachim, Paulsen, Holger, Platzek, Johannes, Kolkhof, Peter
Published in ChemMedChem (01.08.2012)

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Journal Article

Immobilized Triazolium Salts as Precursors to Chiral Carbenes - Rhodium-Catalyzed Asymmetric Hydrosilylation as a First Test Reaction

Immobilized Triazolium Salts as Precursors to Chiral Carbenes - Rhodium-Catalyzed Asymmetric Hydrosilylation as a First Test Reaction

by Enders, Dieter, Gielen, Heike, Breuer, Klaus
Published in Molecules online (01.07.1998)

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Journal Article

Future unmet medical need as a guiding principle for pharmaceutical R&D

Future unmet medical need as a guiding principle for pharmaceutical R&D

by Vennemann, Matthias, Ruland, Vincent, Kruse, Jan-Philip, Harloff, Christine, Trübel, Hubert, Gielen-Haertwig, Heike
Published in Drug discovery today (01.09.2019)

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Journal Article

Polyamino acids

Polyamino acids

by Gielen, Heike
Published in Synlett (01.05.1999)

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Journal Article

Unexpected Active-Site Flexibility in the Structure of Human Neutrophil Elastase in Complex with a New Dihydropyrimidone Inhibitor

Unexpected Active-Site Flexibility in the Structure of Human Neutrophil Elastase in Complex with a New Dihydropyrimidone Inhibitor

by Hansen, Guido, Gielen-Haertwig, Heike, Reinemer, Peter, Schomburg, Dietmar, Harrenga, Axel, Niefind, Karsten
Published in Journal of molecular biology (24.06.2011)

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Journal Article

Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases

Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases

by von Nussbaum, Franz, Li, Volkhart M. -J., Allerheiligen, Swen, Anlauf, Sonja, Baerfacker, Lars, Bechem, Martin, Delbeck, Martina, Fitzgerald, Mary F., Gerisch, Michael, Gielen-Haertwig, Heike, Haning, Helmut, Karthaus, Dagmar, Lang, Dieter, Lustig, Klemens, Meibom, Daniel, Mittendorf, Joachim, Rosentreter, Ulrich, Schaefer, Martina, Schaefer, Stefan, Schamberger, Jens, Telan, Leila A., Tersteegen, Adrian
Published in ChemMedChem (01.07.2015)

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Journal Article

A novel approach to amidines from esters

A novel approach to amidines from esters

by Gielen, Heike, Alonso-Alija, Cristina, Hendrix, Martin, Niewöhner, Ulrich, Schauss, Dagmar
Published in Tetrahedron letters (14.01.2002)

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Journal Article

Novel tetrahydrochinoline derived CETP inhibitors

Novel tetrahydrochinoline derived CETP inhibitors

by Schmeck, Carsten, Gielen-Haertwig, Heike, Vakalopoulos, Alexandros, Bischoff, Hilmar, Li, Volkhart, Wirtz, Gabriele, Weber, Olaf
Published in Bioorganic & medicinal chemistry letters (01.03.2010)

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Journal Article

Diastereoselective synthesis of the first enantiomerically pure (triazolinylidene)ruthenium(II) and -rhodium(III) chelate complexes

Diastereoselective synthesis of the first enantiomerically pure (triazolinylidene)ruthenium(II) and -rhodium(III) chelate complexes

by Enders, D, Gielen, H, Raabe, G, Runsink, J, Teles, JH
Published in Chemische Berichte (01.09.1997)

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Journal Article

Cover Picture: Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases

Cover Picture: Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases

by vonNussbaum, Franz, Li, Volkhart M-J, Allerheiligen, Swen, Anlauf, Sonja, Barfacker, Lars, Bechem, Martin, Delbeck, Martina, Fitzgerald, Mary F, Gerisch, Michael, Gielen-Haertwig, Heike, Haning, Helmut, Karthaus, Dagmar, Lang, Dieter, Lustig, Klemens, Meibom, Daniel, Mittendorf, Joachim, Rosentreter, Ulrich, Schafer, Martina, Schafer, Stefan, Schamberger, Jens, Telan, Leila A, Tersteegen, Adrian
Published in ChemMedChem (01.07.2015)

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Journal Article

Axial Chirality in Square-Planar Metal Complexes

Axial Chirality in Square-Planar Metal Complexes

by Enders, Dieter, Gielen, Heike, Breuer, Klaus
Published in Zeitschrift für Naturforschung. B, A journal of chemical sciences (01.09.1998)

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Journal Article

4-CYCLOALKYL-SUBSTITUTED TETRAHYDROCHINOLINE DERIVATIVES AND USE THEREOF AS MEDICAMENTS

4-CYCLOALKYL-SUBSTITUTED TETRAHYDROCHINOLINE DERIVATIVES AND USE THEREOF AS MEDICAMENTS

by VOLKHART LI, OLAF WEBER, CARSTEN SCHMECK, ALEXANDROS VAKALOPOULOS, MICHAEL THUTEWOHL, HEIKE GIELEN-HAERTWIG, MARTINA WUTTKE, HILMAR BISCHOFF
Year of Publication 04.07.2012

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Patent

COMPUESTO QUIMICO Y SU USO

COMPUESTO QUIMICO Y SU USO

by VOLHART LI, OLAF WEBER, CARSTEN SCHMECK, ALEXANDROS VAKALOPOULOS, MICHAEL THUTEWOHL, HEIKE GIELEN-HAERTWIG, MARTINA WUTTKE, HILMAR BISCHOFF
Year of Publication 09.11.2006

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Patent

Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory ischaemic and remodelling processes

Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory ischaemic and remodelling processes

by DIRK MEURER, SWEN ALLERHEILIGEN, LARS BARFACKER, ULRICH ROSENTRETER, LEILA TELAN, JORG KELDENICH, KEVIN NASH, BARBARA ALBRECHT, MARY F. FITZGERALD, KARL-HEINZ SCHLEMMER, HEIKE GIELEN-HAERTWIG, VOLKHART MIN-JIAN LI
Year of Publication 26.11.2009

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Patent

1,4-DIHYDRO-1,4-DIPHENYLPYRIDINE DERIVATIVES

1,4-DIHYDRO-1,4-DIPHENYLPYRIDINE DERIVATIVES

by LI, VOLKHART, MIN-JIAN, ALLERHEILIGEN, SWEN, NASH, KEVIN, FITZGERALD, MARY, SCHLEMMER, KARL-HEINZ, ROSENTRETER, ULRICH, GIELEN, HEIKE
Year of Publication 30.08.2006

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Patent

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